Pierre Boutouyrie

Summary

Country: France

Publications

  1. ncbi Pharmacological modulation of arterial stiffness
    Pierre Boutouyrie
    HEGP, Assistance publique Hpitaux de Paris, INSERM U970, Universit Paris Descartes, France
    Drugs 71:1689-701. 2011
  2. ncbi [Angiotensin converting enzyme inhibitors and calcium antagonists: a synergistic action for a better prevention of cardiovascular events]
    Pierre Boutouyrie
    Universite Paris Descartes, Faculté de Médecine René Descartes, INSERM, U970, Paris, France
    Therapie 64:241-8. 2009
  3. ncbi Amlodipine-valsartan combination decreases central systolic blood pressure more effectively than the amlodipine-atenolol combination: the EXPLOR study
    Pierre Boutouyrie
    Department of Pharmacology, INSERM U970, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Hypertension 55:1314-22. 2010
  4. ncbi New techniques for assessing arterial stiffness
    P Boutouyrie
    Universite Paris Descartes, Faculté de Médecine René Descartes, INSERM, UMR872, 12, rue Ecole de Médecine 75006 Paris, France
    Diabetes Metab 34:S21-6. 2008
  5. ncbi Carotid and aortic stiffness: determinants of discrepancies
    Anna Paini
    Department of Pharmacology, , INSERM U652, , , Paris, France
    Hypertension 47:371-6. 2006
  6. ncbi Arterial remodeling associates with CKD progression
    Marie Briet
    Department of Pharmacology and Institut National de la Santé et de la Recherche Médicale U970 PARCC, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, 20, rue Leblanc, 75015 Paris, France
    J Am Soc Nephrol 22:967-74. 2011
  7. ncbi Brachial pressure-independent reduction in carotid stiffness after long-term angiotensin-converting enzyme inhibition in diabetic hypertensives
    Anne-Isabelle Tropeano
    Department of Pharmacology and INSERM U 652, Georges Pompidou European Hospital, Paris, France
    Hypertension 48:80-6. 2006
  8. ncbi Aortic stiffness is an independent predictor of fatal stroke in essential hypertension
    Stephane Laurent
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Stroke 34:1203-6. 2003
  9. ncbi Endothelial function and chronic exposure to air pollution in normal male subjects
    Marie Briet
    Faculté de Médecine René Descartes, Universite Paris Descartes, INSERM, UMR872, Paris, France
    Hypertension 50:970-6. 2007
  10. ncbi Evidence for carotid and radial artery wall subclinical lesions in renal fibromuscular dysplasia
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI-U 0107, , Paris, France
    J Hypertens 21:2287-95. 2003

Detail Information

Publications63

  1. ncbi Pharmacological modulation of arterial stiffness
    Pierre Boutouyrie
    HEGP, Assistance publique Hpitaux de Paris, INSERM U970, Universit Paris Descartes, France
    Drugs 71:1689-701. 2011
    ..While the quest continues for 'de-stiffening drugs', so far only advanced glycation endproduct cross-link breakers have shown promise...
  2. ncbi [Angiotensin converting enzyme inhibitors and calcium antagonists: a synergistic action for a better prevention of cardiovascular events]
    Pierre Boutouyrie
    Universite Paris Descartes, Faculté de Médecine René Descartes, INSERM, U970, Paris, France
    Therapie 64:241-8. 2009
    ..They apply to hypertensive patients, but also to coronary artery disease patients and more generally speaking to high cardiovascular risk subjects...
  3. ncbi Amlodipine-valsartan combination decreases central systolic blood pressure more effectively than the amlodipine-atenolol combination: the EXPLOR study
    Pierre Boutouyrie
    Department of Pharmacology, INSERM U970, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Hypertension 55:1314-22. 2010
    ..The amlodipine-valsartan combination decreased central (systolic and pulse) pressure and AIx more than the amlodipine-atenolol combination...
  4. ncbi New techniques for assessing arterial stiffness
    P Boutouyrie
    Universite Paris Descartes, Faculté de Médecine René Descartes, INSERM, UMR872, 12, rue Ecole de Médecine 75006 Paris, France
    Diabetes Metab 34:S21-6. 2008
    ..If we add this evidence to the easiness of performing such measure, carotid to femoral pulse wave velocity is the reference technique for assessing arterial stiffness. Its place in the investigation of patients remains to be precised...
  5. ncbi Carotid and aortic stiffness: determinants of discrepancies
    Anna Paini
    Department of Pharmacology, , INSERM U652, , , Paris, France
    Hypertension 47:371-6. 2006
    ..In these cases, the aorta stiffened more than the carotid artery with age and other cardiovascular risk factors...
  6. ncbi Arterial remodeling associates with CKD progression
    Marie Briet
    Department of Pharmacology and Institut National de la Santé et de la Recherche Médicale U970 PARCC, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, 20, rue Leblanc, 75015 Paris, France
    J Am Soc Nephrol 22:967-74. 2011
    ..In conclusion, maladaptive remodeling of the carotid artery and increased pulse pressure independently associate with faster decline of renal function and progression to ESRD...
  7. ncbi Brachial pressure-independent reduction in carotid stiffness after long-term angiotensin-converting enzyme inhibition in diabetic hypertensives
    Anne-Isabelle Tropeano
    Department of Pharmacology and INSERM U 652, Georges Pompidou European Hospital, Paris, France
    Hypertension 48:80-6. 2006
    ..They also suggest that long-term administration of high doses (8 mg) of perindopril is required to improve carotid structure and function in hypertensive patients with type 2 diabetes...
  8. ncbi Aortic stiffness is an independent predictor of fatal stroke in essential hypertension
    Stephane Laurent
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Stroke 34:1203-6. 2003
    ..The influence of arterial stiffness on the occurrence of stroke has never been demonstrated. Our aim was to establish the relationship between aortic stiffness and stroke death in hypertensive patients...
  9. ncbi Endothelial function and chronic exposure to air pollution in normal male subjects
    Marie Briet
    Faculté de Médecine René Descartes, Universite Paris Descartes, INSERM, UMR872, Paris, France
    Hypertension 50:970-6. 2007
    ..Gaseous pollutants affect large artery endothelial function, whereas particulate matter exaggerates the dilatory response of small arteries to ischemia...
  10. ncbi Evidence for carotid and radial artery wall subclinical lesions in renal fibromuscular dysplasia
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI-U 0107, , Paris, France
    J Hypertens 21:2287-95. 2003
    ..These data indicate the presence of subclinical lesions at arterial sites distant from the renal arteries, suggesting that renal FD is not a focal but a systemic arterial disease...
  11. ncbi Fibromuscular dysplasia
    Pierre Francois Plouin
    Hopital Europeen Georges Pompidou, AP HP, Universite Paris Descartes, Faculte de Medecine, INSERM Unit 772, College de France, Paris, France
    Orphanet J Rare Dis 2:28. 2007
    ..The therapeutic options for securing ruptured intracerebral aneurysms are microvascular neurosurgical clipping and endovascular coiling. Stenosis progression in renal artery FMD is slow and rarely leads to ischemic renal failure...
  12. ncbi Genetic influences on the arterial wall
    Bronwyn Kingwell
    Department of Pharmacology and INSERM U652, Hôpital Européen Georges, Pompidou, Universite Paris Descartes, Faculte de Medecine, Paris, France
    Clin Exp Pharmacol Physiol 34:652-7. 2007
    ..5. These data provide strong evidence that arterial stiffness is affected by the amount and density of stiff wall material and the spatial organization of that material...
  13. ncbi Carotid plaque, arterial stiffness gradient, and remodeling in hypertension
    Hélène Beaussier
    Department of Pharmacology, Inserm U872, Hopital Europeen Georges Pompidou, Universite Paris Descartes, France
    Hypertension 52:729-36. 2008
    ..This may generate a high level of stress concentrations and fatigue, exposing the plaque to a greater risk of rupture...
  14. ncbi Association of menopause and hormone replacement therapy with large artery remodeling
    Anne Gompel
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Hotel Dieu, Paris, France
    Fertil Steril 96:1445-50. 2011
    ..To evaluate the remodeling of large arteries according to age at menopause, duration of menopause, and use of hormone therapy (HT)...
  15. ncbi Multiaxial mechanical characteristics of carotid plaque: analysis by multiarray echotracking system
    Anna Paini
    Department of Pharmacology, Universite Paris Descartes, Faculte de Medecine, INSERM U652, Hopital Europeen Georges Pompidou, Paris, France
    Stroke 38:117-23. 2007
    ..Carotid plaque rupture depends on the various types of mechanical stresses. Our objective was to determine the multiaxial mechanical characteristics of atherosclerotic plaque and adjacent segment of the common carotid artery...
  16. ncbi Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy
    Franck Boccara
    Department of Pharmacology, , , INSERM 652, , Paris, France
    AIDS 20:2395-8. 2006
    ..Age and body mass index were independent determinants of IMT of the CCA. Mean arterial pressure, age, duration of HIV infection and protease inhibitor exposure determined aortic stiffness...
  17. ncbi Increased carotid wall stress in vascular Ehlers-Danlos syndrome
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, , Paris, France
    Circulation 109:1530-5. 2004
    ..CONCLUSIONS: In vEDS patients, an abnormally low intima-media thickness generates a higher wall stress than in control subjects at the site of an elastic artery, which may increase the risk of arterial dissection and rupture...
  18. ncbi Glucose level is a major determinant of carotid intima-media thickness in patients with hypertension and hyperglycemia
    Anne-Isabelle Tropeano
    Department of Pharmacology and INSERM EMI-0107, , Paris, France
    J Hypertens 22:2153-60. 2004
    ....
  19. ncbi Importance of arterial stiffness as cardiovascular risk factor for future development of new type of drugs
    Pierre Boutouyrie
    Faculté de Médecine René Descartes, Universite Paris Descartes, INSERM UMRS872 Equipe 1, 15 rue de l Ecole de Medecine, Paris F 75006, France
    Fundam Clin Pharmacol 22:241-6. 2008
    ..In parallel to this demonstration, points to be improved are the homogenization and spreading of the technique of measurement, the establishment of a reference value database...
  20. ncbi Pulse pressure reduction and cardiovascular protection
    Stephane Laurent
    Department of Pharmacology and INSERM U652, Hopital Europeen Georges Pompidou, Paris, France
    J Hypertens Suppl 24:S13-8. 2006
    ....
  21. ncbi Long-term reduction in aortic stiffness: a 5.3-year follow-up in routine clinical practice
    Hafid Ait-Oufella
    Department of Pharmacology, European Hospital Georges Pompidou, France
    J Hypertens 28:2336-41. 2010
    ..Whether a direct blood pressure-independent reduction in aortic stiffness can occur after several years of antihypertensive treatment has never been unequivocally demonstrated...
  22. ncbi Accelerated arterial stiffening and gene expression profile of the aorta in patients with coronary artery disease
    Celine Fassot
    Faculty of Medicine, University Paris Descartes, Department of Pharmacology, Georges Pompidou European Hospital, Paris, France
    J Hypertens 26:747-57. 2008
    ..Arterial stiffness increases further when CRF is associated with hypertension. We hypothesized that, in patients with mild CRF, aortic gene expression profile would include genes involved in arterial calcifications and enlargement...
  23. ncbi Alpha1-antitrypsin gene polymorphisms are not associated with renal arterial fibromuscular dysplasia
    Jérôme Perdu
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Medical Genetics, Paris, France
    J Hypertens 24:705-10. 2006
    ..Case reports have associated alpha1-antitrypsin deficiency and FMD. The aim of this study was to test the implication of the alpha1-antitrypsin (AAT) gene in a large cohort of patients with renal FMD...
  24. ncbi Expert consensus document on arterial stiffness: methodological issues and clinical applications
    Stephane Laurent
    Department of Pharmacology and Hôpital Européen Georges Pompidou, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, INSERM U652, 20 rue Leblanc, 75015 Paris, France
    Eur Heart J 27:2588-605. 2006
    ....
  25. ncbi Aortic stiffness is reduced beyond blood pressure lowering by short-term and long-term antihypertensive treatment: a meta-analysis of individual data in 294 patients
    Kim Thanh Ong
    Hopitaux de Paris, Hopital Europeen Georges Pompidou, France bINSERM U970, France
    J Hypertens 29:1034-42. 2011
    ..We aimed to determine whether the artery stiffness can be improved because of antihypertensive treatments independently of blood pressure lowering...
  26. ncbi Thromboangiitis obliterans and endothelial function
    Michel Azizi
    Universite Paris Descartes, Faculte de Medecine, Paris, France
    Eur J Clin Invest 40:518-26. 2010
    ..This study compares endothelial function and large artery stiffness between 10 TAO patients assessed during an exacerbation phase and 10 age- and sex-matched control subjects...
  27. ncbi Angiotensinogen gene M235T polymorphism and reduction in wall thickness in response to antihypertensive treatment
    Erwan Bozec
    Department of Pharmacology, INSERM EMI 0107, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Clin Sci (Lond) 105:637-44. 2003
    ..In conclusion, these data suggest that the angiotensinogen TT genotype at position 235 is a genetic marker for early carotid atherosclerosis in a hypertensive population and its regression under antihypertensive treatment...
  28. ncbi Age-independent association between arterial and bone remodeling in mild-to-moderate chronic kidney disease
    Marie Briet
    Universite Paris Descartes, INSERM, UMR872, Paris, France
    Nephrol Dial Transplant 25:191-7. 2010
    ..We made the hypothesis that bone disease could be associated with the carotid outward remodeling in parallel with the decline of renal function in this population...
  29. ncbi Cardiovascular risk assessment through target organ damage: role of carotid to femoral pulse wave velocity
    Pierre Boutouyrie
    Universite Paris Descartes, Faculté de Médecine René Descartes, INSERM, UMR872, and Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Pharmacology, Paris, France
    Clin Exp Pharmacol Physiol 35:530-3. 2008
    ....
  30. ncbi Mechanical and structural characteristics of carotid plaques by combined analysis with echotracking system and MR imaging
    Hélène Beaussier
    Department of Pharmacology and INSERM U970, Hopital Europeen Georges Pompidou, Paris, France
    JACC Cardiovasc Imaging 4:468-77. 2011
    ..The purpose of this study was to correlate the arterial mechanics of carotid atherosclerotic plaques assessed from echotracking with their composition by high-resolution magnetic resonance imaging (HR-MRI)...
  31. ncbi Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial
    Kim Thanh Ong
    Assistance Publique, Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Lancet 376:1476-84. 2010
    ..Our aim was to assess the ability of celiprolol, a ?(1)-adrenoceptor antagonist with a ?(2)-adrenoceptor agonist action, to prevent arterial dissections and ruptures in vascular Ehlers-Danlos syndrome...
  32. ncbi Arterial stiffness and angiotensinogen gene in hypertensive patients and mutant mice
    Erwan Bozec
    Department of Pharmacology, Hôpital Européen Georges Pompidou and Institut National de la Santé et de la Recherche Médicale EMI 0107, Paris, France
    J Hypertens 22:1299-307. 2004
    ....
  33. ncbi Rationale, design and methods of the CASHMERE study
    Tabassome Simon
    Department of Pharmacology, Paris VI University, Saint Antoine University Hospital AP HP, Paris, France
    Fundam Clin Pharmacol 18:131-8. 2004
    ..The results are expected for 2007...
  34. ncbi Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, , Paris, France
    Hypertension 39:10-5. 2002
    ..This study provides the first direct evidence in a longitudinal study that aortic stiffness is an independent predictor of primary coronary events in patients with essential hypertension...
  35. ncbi Arterial and renal consequences of partial genetic deficiency in tissue kallikrein activity in humans
    Michel Azizi
    Centre d Investigations Cliniques 9201, Assistance Publique des Hôpitaux de Paris and INSERM, Universite Paris V, Paris, France
    J Clin Invest 115:780-7. 2005
    ....
  36. ncbi Structural and genetic bases of arterial stiffness
    Stephane Laurent
    Department of Pharmacology and INSERM EMI 107, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 45:1050-5. 2005
    ..These data provide strong evidence that arterial stiffness is affected by the amount and density of stiff wall material and the spatial organization of that material...
  37. ncbi [Vascular Ehlers-Danlos syndrome]
    Jérôme Perdu
    Groupe Multidisciplinaire de Prise en Charge du Syndrome d Ehlers Danlos Vasculaire, Hopital Europeen Georges Pompidou, Paris
    Presse Med 35:1864-75. 2006
    ....
  38. ncbi Paris Prospective Study III: a study of novel heart rate parameters, baroreflex sensitivity and risk of sudden death
    Jean Philippe Empana
    Paris Cardiovascular Research Centre, University Paris Descartes, and Assistance Publique des Hopitaux de Paris, UMR S970, Paris, France
    Eur J Epidemiol 26:887-92. 2011
    ..This unique study should provide new insights into the regulation of heart rate and blood pressure and should enable to identify novel heart rate parameters that are associated with sudden death...
  39. ncbi Arterial stiffness and stroke in hypertension: therapeutic implications for stroke prevention
    Stephane Laurent
    Department of Pharmacology and INSERM EMI 107, Hopital Europeen Georges Pompidou, 20 rue Leblanc, Paris, 75015, France
    CNS Drugs 19:1-11. 2005
    ....
  40. ncbi Increased stiffness of the carotid wall material in patients with spontaneous cervical artery dissection
    David Calvet
    Department of Pharmacology and INSERM EMI 0107, , Paris, France
    Stroke 35:2078-82. 2004
    ..Higher stiffness of carotid wall material and circumferential wall stress could increase the risk of dissection in these patients...
  41. ncbi Risk assessment for severe clinical attachment loss in an adult population
    Philippe Bouchard
    Department of Periodontology, Service of Odontology, , AP-HP, Paris 7-Denis Diderot University, UFR of Odontology, Paris, France
    J Periodontol 77:479-89. 2006
    ..The patient profile for severe clinical attachment loss also included body mass index and white blood cell count. Occasional drinking may be associated with decreased severity of CAL...
  42. ncbi Frequent and widespread vascular abnormalities in human signal transducer and activator of transcription 3 deficiency
    Marie Olivia Chandesris
    Hematology Department, Necker Children s Hospital, Assistance Publique Hopitaux de Paris, 149 rue de Sevres, Paris, France
    Circ Cardiovasc Genet 5:25-34. 2012
    ..Although vascular abnormalities have been reported in some patients, the prevalence, characteristics, and etiology of these features have yet to be described...
  43. ncbi Arterial remodeling and stiffness in patients with pseudoxanthoma elasticum
    Dominique P Germain
    Service de Pharmacologie et INSERM EMI 0107, , Paris, France
    Arterioscler Thromb Vasc Biol 23:836-41. 2003
    ..CONCLUSIONS: Phenotypic changes of superficial arteries in patients with PXE were represented by a thickening of the carotid artery and a reduced stiffness of the radial artery and predominated in older female patients...
  44. ncbi Inheritance of arterial lesions in renal fibromuscular dysplasia
    J Perdu
    AP HP, Department of Genetics, Hopital Europeen Georges Pompidou, Paris, France
    J Hum Hypertens 21:393-400. 2007
    ..The carotid score obtained by high-resolution echotracking may provide a non-invasive surrogate marker for renal FMD of potential value for use in linkage strategies on large pedigrees...
  45. ncbi [Large artery and left ventricular remodelling in Fabry disease.]
    Pierre Boutouyrie
    Universite Paris Descartes, Faculte de Medecine, Département de Pharmacologie et Inserm U 652, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, 20 rue Leblanc, 75015 Paris, France
    Med Sci (Paris) 21:30-2. 2005
    ..These results show that tissues of the cardiovascular system tend to be oversensitive to trophic signals in patients with Fabry disease. double dagger...
  46. ncbi Local pulse pressure and regression of arterial wall hypertrophy during long-term antihypertensive treatment
    P Boutouyrie
    Department of Pharmacology, INSERM U 337, Broussais Hospital, Paris, France
    Circulation 101:2601-6. 2000
    ....
  47. ncbi Local pulse pressure is a major determinant of large artery remodelling
    S Laurent
    Department of Pharmacology and EMI INSERM 0107, Hopital Europeen Georges Pompidou, Paris, France
    Clin Exp Pharmacol Physiol 28:1011-4. 2001
    ..4. We suggest that the effects of pulse pressure on large artery remodelling may explain part of its predictive value on cardiovascular events...
  48. ncbi Lack of association between renin-angiotensin system, gene polymorphisms, and wall thickness of the radial and carotid arteries
    X Girerd
    From the Department of Internal Medicine and INSERM U337, the Department of Pharmacology and INSERM U337 and the Laboratory of Molecular Biology, Broussais Hospital, Paris, France
    Hypertension 32:579-83. 1998
    ..These results suggest that these gene polymorphisms have an undetectable role in the geometry of the radial and carotid arteries compared with usual determinants such as blood pressure and age...
  49. ncbi Pathophysiology of hypertension in the elderly
    Stephane Laurent
    Department of Pharmacology, EMI U 0107 Inserm, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Am J Geriatr Cardiol 11:34-9. 2002
    ..In this elderly population, further research is needed concerning the pathophysiology, epidemiology, and pharmacology of hypertension...
  50. ncbi Influence of tamoxifen on carotid intima-media thickness in postmenopausal women
    T Simon
    Department of Pharmacology, St Antoine University Hospital, Paris, France
    Circulation 106:2925-9. 2002
    ..The goal of this study was to determine the influence of tamoxifen on IMT-CCA in menopausal women...
  51. ncbi Arterial remodelling in Fabry disease
    P Boutouyrie
    Department of Pharmacology, INSERM EMI 107, , Paris, France
    Acta Paediatr Suppl 91:62-6. 2002
    ..CONCLUSION: This study presents evidence of a major increase in arterial wall thickness and distensibility, measurable at the site of a medium-sized artery, in a cohort of patients with classic Fabry disease...
  52. ncbi Renal artery diameter, renal function and resistant hypertension in patients with low-to-moderate renal artery stenosis
    Luca Zanoli
    Department of Internal Medicine, University of Catania, Italy
    J Hypertens 30:600-7. 2012
    ..We aimed to identify the association of reference diameter and minimal luminal renal artery diameter with glomerular filtration rate (GFR) and resistant hypertension in a high cardiovascular risk population...
  53. ncbi Ambulatory arterial stiffness index does not accurately assess arterial stiffness
    Jan G Kips
    Heymans Institute of Pharmacology, Gent University, Gent, Belgium
    J Hypertens 30:574-80. 2012
    ..Using a previously validated one-dimensional computer model of the arterial circulation, the relative importance of the different determinants of the AASI was explored...
  54. ncbi Antihypertensive effects of fasidotril, a dual inhibitor of neprilysin and angiotensin-converting enzyme, in rats and humans
    S Laurent
    Department of Pharmacology and INSERM U 337, Broussais Hospital, Paris, France
    Hypertension 35:1148-53. 2000
    ....
  55. ncbi Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients
    S Laurent
    Department of Pharmacology and INSERM U 337, Broussais Hospital, Paris, France
    Hypertension 37:1236-41. 2001
    ..This study provides the first direct evidence that aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with essential hypertension...
  56. ncbi Arterial stiffness and enlargement in mild-to-moderate chronic kidney disease
    M Briet
    Department of Physiology, , , Paris, France
    Kidney Int 69:350-7. 2006
    ..Arterial enlargement and increased arterial stiffness occur in parallel with the decline in renal function in patients with mild-to-moderate CKD...
  57. ncbi Effects of acupuncture on radial artery hemodynamics: controlled trials in sensitized and naive subjects
    P Boutouyrie
    , , Paris, France
    Am J Physiol Heart Circ Physiol 280:H628-33. 2001
    ..Our results demonstrate that real acupuncture is associated with an objective vasodilatation of the radial artery in patients regularly exposed to acupuncture, but not in naive subjects...
  58. ncbi Compressibility of the carotid artery in patients with pseudoxanthoma elasticum
    P Boutouyrie
    Department of Pharmacology, INSERM EMI 0107, , Paris, France
    Hypertension 38:1181-4. 2001
    ..In conclusion, CAW was measurable in vivo and noninvasively in humans. The higher CAW of PXE patients compared with that of control subjects suggests that proteoglycans are important determinants of compressibility...
  59. ncbi Heart rate, arterial stiffness, and wave reflections in paced patients
    P Albaladejo
    UPRES 392, , , France
    Hypertension 38:949-52. 2001
    ..These results are important to consider for a better understanding of cardiovascular risk and the mechanism of white-coat hypertension...
  60. ncbi Mechanical properties and structure of carotid arteries in mice lacking desmin
    P Lacolley
    Institut National de la Sante et de la Recherche Medicale, INSERM U337, 15 rue de l Ecole de Medecine, 75270 Paris Cedex 06, France
    Cardiovasc Res 51:178-87. 2001
    ..Our aim was to determine in desmin homozygous mutant mice the viscoelastic properties, the mechanical strength and the structure of the carotid artery...
  61. ncbi [Effect of acupuncture on radial artery hemodynamics. Two controlled studies in pre-exposed and naive healthy subjects]
    P Boutouyrie
    Service de pharmacologie clinique et EMI-U 0107 INSERM, , 75015 Paris
    Arch Mal Coeur Vaiss 94:913-7. 2001
    ..Our results demonstrate that real acupuncture can determine an objective vasodilatation of the radial artery in patients regularly exposed to acupuncture, but not in naive subjects...
  62. ncbi [Arterial ageing and coronary artery disease: physiopathological and epidemiological data]
    P Boutouyrie
    Service de Pharmacologie, HEGP, 20, rue Leblanc, 75908 Paris
    Arch Mal Coeur Vaiss 99:19-24. 2006
    ..This predictive value is a complement to risk algorithms (SCORE, Framingham) and further predicts the coronary risk. Remodelling and arterial rigidity constitute disease of the artery as a target organ. Arch Mal Coeur Vaiss..