M Bagot

Summary

Country: France

Publications

  1. ncbi Engagement of ILT2/CD85j in Sézary syndrome cells inhibits their CD3/TCR signaling
    Maria Nikolova
    INSERM 448 and Dermatology Department, Faculté de Médecine de Créteil, Creteil, France
    Blood 100:1019-25. 2002
  2. ncbi [Epidermotropic T cell lymphomas as models for tumor progression]
    Martine Bagot
    Service de Dermatologie, AP HP, Hopital Henri Mondor, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France
    Med Sci (Paris) 22:192-6. 2006
  3. ncbi Functional inhibitory receptors expressed by a cutaneous T cell lymphoma-specific cytolytic clonal T cell population
    M Bagot
    INSERM U448, Paris XII University, Hopital Henri Mondor, AP HP, Creteil, France
    J Invest Dermatol 115:994-9. 2000
  4. ncbi Immunopathogenesis of cutaneous T-cell lymphomas
    Martine Bagot
    Department of Dermatology, Paris XII University, INSERM U448, 8 rue du General Sarrail, 94010 Creteil, France
    Hematol Oncol Clin North Am 17:1313-7, vii. 2003
  5. ncbi Crosstalk between tumor T lymphocytes and reactive T lymphocytes in cutaneous T cell lymphomas
    M Bagot
    Department of Dermatology and Inserm U448, Paris XII University, Creteil, France
    Ann N Y Acad Sci 941:31-8. 2001
  6. ncbi CD4(+) cutaneous T-cell lymphoma cells express the p140-killer cell immunoglobulin-like receptor
    M Bagot
    INSERM U448 and Service de Dermatologie de l hopital Henri Mondor, Creteil, France
    Blood 97:1388-91. 2001
  7. ncbi [Contribution of immunotherapy to the treatment of T-cell lymphoma of the skin]
    M Bagot
    Service de Dermatologie et INSERM U448, Hopital Henri Mondor, Creteil
    Presse Med 28:1911-6. 1999
  8. ncbi Isolation of a CD8alphaalpha+ CD4- tumour T-cell clone with cytotoxic activity from a CD4+ CD8- cutaneous T-cell lymphoma
    M Nikolova
    INSERM U448, Department of Dermatology, , , France
    Br J Dermatol 148:24-9. 2003
  9. ncbi Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma
    M H Delfau-Larue
    Departments of Immunobiology, Pathology, Biostatistics and Medical Informatics, and Dermatology, Hospital Henri Mondor, Assistance Publique Hopitaux de Paris, Creteil, France
    Blood 96:2987-92. 2000
  10. ncbi Identification of cell surface molecules characterizing human cutaneous T-cell lymphomas
    M Nikolova
    INSERM U448, , Hopital Henri Mondor, , France
    Leuk Lymphoma 43:741-6. 2002

Detail Information

Publications65

  1. ncbi Engagement of ILT2/CD85j in Sézary syndrome cells inhibits their CD3/TCR signaling
    Maria Nikolova
    INSERM 448 and Dermatology Department, Faculté de Médecine de Créteil, Creteil, France
    Blood 100:1019-25. 2002
    ..Therefore, the resistance to apoptosis of Sézary cells may result from distinct mechanisms including cytokine-induced high levels of bcl-2 and specific expression of inhibitory receptors involved in lymphocyte survival...
  2. ncbi [Epidermotropic T cell lymphomas as models for tumor progression]
    Martine Bagot
    Service de Dermatologie, AP HP, Hopital Henri Mondor, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France
    Med Sci (Paris) 22:192-6. 2006
    ....
  3. ncbi Functional inhibitory receptors expressed by a cutaneous T cell lymphoma-specific cytolytic clonal T cell population
    M Bagot
    INSERM U448, Paris XII University, Hopital Henri Mondor, AP HP, Creteil, France
    J Invest Dermatol 115:994-9. 2000
    ..These results are the first evidence that inhibitory receptor expression can lead to the inhibition of cutaneous T cell lymphoma-specific T cell responses...
  4. ncbi Immunopathogenesis of cutaneous T-cell lymphomas
    Martine Bagot
    Department of Dermatology, Paris XII University, INSERM U448, 8 rue du General Sarrail, 94010 Creteil, France
    Hematol Oncol Clin North Am 17:1313-7, vii. 2003
    ..Little is known about the factors that drive a mature T-cell clone to accumulate in the skin, despite the feedback mechanisms that normally control immune response. This article discusses the identification of tumor-specific antigens...
  5. ncbi Crosstalk between tumor T lymphocytes and reactive T lymphocytes in cutaneous T cell lymphomas
    M Bagot
    Department of Dermatology and Inserm U448, Paris XII University, Creteil, France
    Ann N Y Acad Sci 941:31-8. 2001
    ..Finally, we present recent data on new antigen structures expressed both by long-term CTCL lines and uncultured tumor cells...
  6. ncbi CD4(+) cutaneous T-cell lymphoma cells express the p140-killer cell immunoglobulin-like receptor
    M Bagot
    INSERM U448 and Service de Dermatologie de l hopital Henri Mondor, Creteil, France
    Blood 97:1388-91. 2001
    ..This finding is likely to be important both for the pathophysiology and for the clinical treatment of patients with CTCL...
  7. ncbi [Contribution of immunotherapy to the treatment of T-cell lymphoma of the skin]
    M Bagot
    Service de Dermatologie et INSERM U448, Hopital Henri Mondor, Creteil
    Presse Med 28:1911-6. 1999
    ..Injections of immunogenic peptides associated or not with dendritic cells or injection of DNA coding for these tumor antigens are other possibilities...
  8. ncbi Isolation of a CD8alphaalpha+ CD4- tumour T-cell clone with cytotoxic activity from a CD4+ CD8- cutaneous T-cell lymphoma
    M Nikolova
    INSERM U448, Department of Dermatology, , , France
    Br J Dermatol 148:24-9. 2003
    ..However, in these cases, there has been no demonstration that the phenotypic change involved the same T-cell clone. The present study is the first report of the phenotypic heterogeneity of the tumour clonal cell population in CTCL...
  9. ncbi Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma
    M H Delfau-Larue
    Departments of Immunobiology, Pathology, Biostatistics and Medical Informatics, and Dermatology, Hospital Henri Mondor, Assistance Publique Hopitaux de Paris, Creteil, France
    Blood 96:2987-92. 2000
    ..A multicenter prospective study is under way to establish the prognostic value of circulating tumor cells...
  10. ncbi Identification of cell surface molecules characterizing human cutaneous T-cell lymphomas
    M Nikolova
    INSERM U448, , Hopital Henri Mondor, , France
    Leuk Lymphoma 43:741-6. 2002
    ..The identification of these new structures on circulating SS tumor cells seems to be important both for the understanding of CTCL pathophysiology and for the clinical management of SS patients...
  11. ncbi Triggering CD101 molecule on human cutaneous dendritic cells inhibits T cell proliferation via IL-10 production
    A Bouloc
    INSERM U448, Paris XII University, Creteil, France
    Eur J Immunol 30:3132-9. 2000
    ..Our results demonstrate that the CD101 triggering on cutaneous DC inhibits T cell proliferation via IL-10 production, suggesting an important regulatory role played by the CD101 molecule on DC during T cell activation...
  12. ncbi Erythrodermic cutaneous T-cell lymphoma with disseminated pustulosis. Production of high levels of interleukin-8 by tumour cells
    E Poszepczynska
    Department of Dermatology, AP-HP, , , France
    Br J Dermatol 144:1073-9. 2001
    ..The production of IL-8 by tumour T cells could explain this unusual clinical and histopathological presentation of cutaneous T-cell lymphoma as disseminated pustulosis...
  13. ncbi [Severe tularaemia mimicking glandular tuberculosis during adalimumab therapy]
    M P Konstantinou
    Service de Dermatologie, Hopital Henri Mondor, AP HP, Universite Paris XII, 94010 Creteil Cedex, France
    Ann Dermatol Venereol 136:718-22. 2009
    ..We report a case of tularaemia in its ulceroglandular form occurring during methotrexate and adalimumab treatment (Humira) for rheumatoid arthritis...
  14. ncbi [Severe necrotizing myopathy subsequent to Merkel cell carcinoma]
    O Hocar
    Service de Dermatologie, Hopital Henri Mondor, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil Cedex, France
    Ann Dermatol Venereol 138:130-4. 2011
    ..We report the first case of severe necrotizing myopathy with anti-Hu antibodies complicating MCC...
  15. ncbi Leucoderma associated with flares of erythrodermic cutaneous T-cell lymphomas: four cases. The French Study Group of Cutaneous Lymphomas
    A Bouloc
    Department of Dermatology, Hospital Henri Mondor AP HP, Paris XII University Créteil, 94010 Creteil, France
    Br J Dermatol 143:832-6. 2000
    ..It is suggested that the hypopigmentation could be due to the cytotoxicity of tumour or reactional lymphocytes directed against melanocytes...
  16. ncbi Polymerase chain reaction analysis of immunoglobulin gene rearrangement in cutaneous lymphoid hyperplasias. French Study Group for Cutaneous Lymphomas
    A Bouloc
    Department of Dermatology, Hospital Henri Mondor, Creteil, France
    Arch Dermatol 135:168-72. 1999
    ..We therefore studied cases of cutaneous lymphoid hyperplasia by polymerase chain reaction analysis...
  17. ncbi Two atypical cases of cutaneous gamma/delta T-cell lymphomas
    A Caudron
    Department of Dermatology, AP HP, Saint Louis Hospital, Paris, France
    Dermatology 222:297-303. 2011
    ..CGD-TCL is also a heterogeneous entity and ? PCR and EBV-encoded RNA probe to detect an EBV latent infection may help diagnose and characterize these cutaneous lymphomas...
  18. ncbi Functional characterization of neurotensin receptors in human cutaneous T cell lymphoma malignant lymphocytes
    M Ramez
    INSERM U448, Faculté de Médecine de Créteil, Service de Dermatologie, Hopital Henri Mondor, 94010 Creteil Cedex, France
    J Invest Dermatol 117:687-93. 2001
    ..This suggests that neurotensin in skin can play a role in the disease by locally limiting the growth of the cutaneous T cell lymphoma tumor cells in response to cytokines and by enhancing their chemotaxis capacity...
  19. ncbi [Auto-immune thyroiditis and drug reaction with eosinophilia and systemic symptoms (DRESS) associated with HHV-6 viral reactivation]
    E Funck-Brentano
    Service de Dermatologie, Hopital Henri Mondor, Universite Paris XII, centre de référence des maladies bulleuses immunologiques et toxiques, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France
    Ann Dermatol Venereol 138:580-5. 2011
    ..Its physiopathology includes immunological disorders associated with human herpes virus (HHV) reactivation. We report two cases of auto-immune thyroiditis occurring in the context of DRESS syndrome associated with HHV-6 reactivation...
  20. ncbi CD101 expression by Langerhans cell histiocytosis cells
    A Bouloc
    Department of Dermatology INSERM U448 Department of Pathology, Hopital Henri Mondor, Creteil, France
    Histopathology 36:229-32. 2000
    ..We wanted to determine if CD101 expression could be helpful for the diagnosis of LCH in conjunction with other markers (CD1a, S100 protein), and could be predictive of the evolution and dissemination of the disease...
  21. ncbi [Cutaneous CD8+ epidermotropic cytotoxic T-cell lymphoma with aggressive course]
    E Poszepczynska-Guigne
    Service de Dermatologie, Hopital Henri Mondor, Creteil, France
    Ann Dermatol Venereol 133:253-6. 2006
    ..Only about twenty cases have been described in the literature. Below we report a case involving unusual association of cutaneous vasculitis and lymphoproliferation...
  22. ncbi Blastic plasmacytoid dendritic cell neoplasm: is transplantation the treatment of choice?
    S Dalle
    Department of Dermatology, Universite Claude Bernard Lyon 1, Hospices Civils de Lyon, INSERM U590, Lyon, France
    Br J Dermatol 162:74-9. 2010
    ..Local treatments, such radiation therapy, are definitively useless. Regardless of the initial extension of the disease, in our experience only bone marrow transplantation significantly improved the outcome...
  23. ncbi Minimal residual disease in mycosis fungoides follow-up can be assessed by polymerase chain reaction
    E Poszepczynska-Guigne
    Department of Dermatology, Henri Mondor Hospital, University Paris XII, APHP, 51 Avenue du Marechal de Lattre de Tassigny, 94010 Creteil Cedex, France
    Br J Dermatol 148:265-71. 2003
    ..T-cell receptor (TCR) gene rearrangement analysis, i.e. T-cell clonality, using polymerase chain reaction (PCR) is a routine method used to assess the presence of a cutaneous dominant T-cell clone in mycosis fungoides (MF)...
  24. ncbi Open trial of ciclosporin treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis
    L Valeyrie-Allanore
    Department of Dermatology, Reference Centre for Toxic and Autoimmune Blistering Diseases, Universite Paris XII, F 94010 Cre teil, France
    Br J Dermatol 163:847-53. 2010
    ..The mean ± SD hospital stay was 16.2 +/- 9.1 days.Conclusions Both the death rate and the progression of detachment seemed lower than expected, suggesting a possible usefulness of ciclosporin in SJS and TEN that needs to be confirmed...
  25. ncbi [Subacute cutaneous lupus erythematosus and cancer: two cases and literature review]
    A Gantzer
    Service de Dermatologie, Hopital Henri Mondor, AP HP, faculté Paris 12, 51 Avenue du Marechal de Lattre de Tassigny, Creteil, France
    Ann Dermatol Venereol 138:409-17. 2011
    ..It is remarkable as a paraneoplastic syndrome (12 cases in the literature). We report two cases of subacute cutaneous lupus erythematosus occurring in patients treated for metastatic breast adenocarcinoma...
  26. ncbi Covalent binding of carbamazepine reactive metabolites to P450 isoforms present in the skin
    P Wolkenstein
    Department of Dermatology, CHU Henri Mondor, Paris XII University, Creteil, France
    Chem Biol Interact 113:39-50. 1998
    ..Consequently, the production in epidermis of carbamazepine reactive metabolites is theoretically possible with formation of P450 adduct metabolites...
  27. ncbi [Wells' cellulitis and bacterial necrotizing cellulitis induced by anakinra]
    M Livory
    Service de Dermatologie, Hopital Henri Mondor, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil Cedex, France
    Ann Dermatol Venereol 135:839-42. 2008
    ..It is used in the treatment of rheumatoid arthritis. The most frequent side effects are injection site reactions, which seem to have a toxic mechanism...
  28. ncbi [Bilateral elastofibroma dorsi]
    O Hocar
    Service de Dermatologie, Hopital Henri Mondor, Creteil, France
    Ann Dermatol Venereol 139:41-5. 2012
    ..There are few reports in the dermatological literature since it rarely develops in skin or subcutaneous tissue...
  29. ncbi [Infective endocarditis in a dermatology unit]
    M P Konstantinou
    Service de Dermatologie, Hopital Henri Mondor, AP HP, Universite Paris XII, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil Cedex, France
    Ann Dermatol Venereol 136:869-75. 2009
    ..Although the dermatological signs of endocarditis can vary, they must be routinely sought where there is a suspicion of IE. The aim of this study was to reveal the diversity of clinical manifestations of IE in a dermatology unit...
  30. ncbi CD101 is expressed by skin dendritic cells. Role in T-lymphocyte activation
    M Bagot
    INSERM U448, IM3, Hopital Henri Mondor, Creteil, France
    Tissue Antigens 50:439-48. 1997
    ..Thus, CD101 which is expressed on a subset of circulating T lymphocytes, has also been found on a subpopulation of LC-like DC. This molecule plays a major role in the activation of T cells by skin DC...
  31. ncbi [Two cases of psoas abscesses caused by group A beta-haemolytic streptococcal infection with a cutaneous portal of entry]
    E Routier
    Service de Dermatologie, Hopital Henri Mondor, AP HP, 94010 Creteil, France
    Ann Dermatol Venereol 137:369-72. 2010
    ..We report two cases of psoas abscesses caused by group A beta-haemolytic streptococcal infection having a cutaneous portal of entry...
  32. ncbi [Erythema elevatum diutinum associated with pyoderma gangrenosum in an HIV-positive patient]
    L Maksimovic
    Departement de Pathologie, Groupe Hospitalier Henri Mondor Albert Chenevier, AP HP, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France
    Ann Dermatol Venereol 137:386-90. 2010
    ..We report the association of EED and pyoderma gangrenosum in a patient infected with HIV...
  33. ncbi Histopathologically dysplastic neurofibromas in neurofibromatosis 1: diagnostic criteria, prevalence and clinical significance
    L Valeyrie-Allanore
    Department of Dermatology, National Neurofibromatosis Centre, Paris XII University, Henri Mondor Hospital, AP HP, F 94010 Créteil Cedex, France
    Br J Dermatol 158:1008-12. 2008
    ..Malignant peripheral nerve sheath tumours (MPNSTs) correspond to the most frequent and aggressive neoplasic complications associated with poor prognosis in neurofibromatosis 1...
  34. ncbi Prognostic factors in primary cutaneous large B-cell lymphomas: a European multicenter study
    F Grange
    Department of Dermatology, Hopital Pasteur, Colmar, France
    J Clin Oncol 19:3602-10. 2001
    ..This distinction on the basis of site has been debated. Our aim was to identify independent prognostic factors in a large European multicenter series of PCLBCL...
  35. ncbi [Treatment of HIV facial lipoatrophy with a submalar porous polyethylene implant (Medpor)]
    O Claude
    Service de chirurgie plastique reconstructrice et esthétique, Hopital Henri Mondor, Universite Paris XII, 51 Avenue du Marechal de Lattre de Tassigny, Creteil, France
    Ann Chir Plast Esthet 54:21-8. 2009
    ..No complications occurred and results remain natural. Porous polyethylene implant (Medpor) is our treatment of choice for mild to severe facial lipoatrophy. Besides these implants could be removed easily later if needed...
  36. ncbi [Psoriatic arthritis]
    P Claudepierre
    Service de Rhumatologie, Hopital Henri Mondor, 51 Avenue du Marechal de Lattre de Tassigny, 94010 Creteil, France
    Ann Dermatol Venereol 135:S263-8. 2008
    ..Therapeutic strategies must be adapted to the clinical presentation...
  37. ncbi Significance of circulating T-cell clones in Sezary syndrome
    Nicolas Ortonne
    INSERM U659, , , , France
    Blood 107:4030-8. 2006
    ..Identification of the malignant cells in Sézary syndrome cannot be achieved by T-cell clonality studies or by TCR Vbeta monoclonal antibody (mAb) analysis alone; it also relies on CD158k phenotyping...
  38. ncbi CD158k/KIR3DL2 is a new phenotypic marker of Sezary cells: relevance for the diagnosis and follow-up of Sezary syndrome
    Ewa Poszepczynska-Guigné
    INSERM U448, Hopital Henri Mondor, Creteil, France
    J Invest Dermatol 122:820-3. 2004
    ..Our findings suggest that the CD158k marker could be a useful tool for the evaluation of the circulating tumoral burden and the follow-up of patients with Sezary syndrome...
  39. ncbi Killer cell immunoglobulin-like receptor expression delineates in situ Sézary syndrome lymphocytes
    Janine Wechsler
    , , , France
    J Pathol 199:77-83. 2003
    ..The identification of this KIR also differentiates between lupus erythematosus and lichen planus, which are both diseases with dense benign lymphocytic infiltrates...
  40. ncbi Circulating natural killer lymphocytes are potential cytotoxic effectors against autologous malignant cells in sezary syndrome patients
    Jean-David Bouaziz
    INSERM 659, , , , France
    J Invest Dermatol 125:1273-8. 2005
    ..These findings indicate that antitumor-mediated NK lymphocyte cytotoxic activity can be triggered in patients with CTCL and raise the possibility of developing novel therapeutic strategies by stimulating their innate immunity...
  41. ncbi SC5 mAb represents a unique tool for the detection of extracellular vimentin as a specific marker of Sezary cells
    Delphine Huet
    , University of Paris XII, , Henri Mondor Hospital, Department of Dermatology, , France
    J Immunol 176:652-9. 2006
    ..Finally, as a probable outcome of vimentin cell surface expression, autoantibodies against vimentin were found in the sera of Sézary syndrome patients...
  42. ncbi Identification of a novel CD160+ CD4+ T-lymphocyte subset in the skin: a possible role for CD160 in skin inflammation
    Sofia Abecassis
    INSERM Unit 659, Creteil, France
    J Invest Dermatol 127:1161-6. 2007
    ..Thus, we hypothesize that the unique CD4+ CD160+ lymphocyte subset plays a role in the pathogenesis of skin inflammation...
  43. ncbi Polymorphic expression of CD158k/p140/KIR3DL2 in Sézary patients
    Philippe Musette
    Blood 101:1203. 2003
  44. ncbi Value of the CD8-CD3 ratio for the diagnosis of mycosis fungoides
    Nicolas Ortonne
    Department of Pathology, , , France
    Mod Pathol 16:857-62. 2003
    ..Although not absolutely specific, a low CD8-CD3 ratio in the epidermal component of a lymphocytic infiltrate supports the diagnosis of mycosis fungoides. It can be evaluated in routine practice using a semiquantitative approach...
  45. ncbi Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis
    Amal Nassif
    INSERM U 448 Department of Dermatology, , , , France
    J Invest Dermatol 118:728-33. 2002
    ..These results challenge several current concepts and could support new therapeutic approaches...
  46. ncbi European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas
    Nancy J Senff
    Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands
    Blood 112:1600-9. 2008
    ..They may therefore contribute to uniform staging and treatment and form the basis for future clinical trials in patients with a CBCL...
  47. ncbi Treatment of Sézary syndrome with bexarotene after IFNalpha and methotrexate failure
    Martine Bagot
    Department of Dermatology, , , France
    Dermatol Clin 26:27-9. 2008
  48. ncbi Bcl-2 protein expression is the strongest independent prognostic factor of survival in primary cutaneous large B-cell lymphomas
    Florent Grange
    Department of Dermatology, Hopital Pasteur, Colmar Cedex, France
    Blood 103:3662-8. 2004
    ..0001). A new prognostic classification of primary cutaneous B-cell lymphoma should be based primarily on bcl-2 protein expression rather than the location of skin lesions...
  49. ncbi Cutaneous T-cell lymphoma. Preface
    Martine Bagot
    Dermatol Clin 26:V. 2008
  50. ncbi Treatment of early-stage mycosis fungoides with twice-weekly applications of mechlorethamine and topical corticosteroids: a prospective study
    Julie de Quatrebarbes
    Department of Dermatology and Pathology, University of Rouen, Rouen, France
    Arch Dermatol 141:1117-20. 2005
    ..The decreased frequency of applications provides an advantage to the patient by being easy to use with limited adverse effects...
  51. ncbi Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells
    Amal Nassif
    INSERM U448, , Universite Paris XII, , France
    J Allergy Clin Immunol 114:1209-15. 2004
    ..CONCLUSION: These results strongly suggest that drug-specific, MHC class I-restricted, perforin/granzyme-mediated cytotoxicity probably has a primary role in TEN...
  52. ncbi Clinical experience: practical management of five patients with cutaneous T-cell lymphoma (CTCL)-related symptoms
    Reinhard Dummer
    Department of Dermatology, University Hospital of Zurich, Switzerland
    Semin Oncol 33:S26-32. 2006
    ..This article provides details of five real-life case studies to illustrate how cutaneous T-cell lymphoma management can be tailored to the needs of each individual patient...
  53. ncbi Heterogeneous abnormalities of CCND1 and RB1 in primary cutaneous T-Cell lymphomas suggesting impaired cell cycle control in disease pathogenesis
    Xin Mao
    Skin Tumour Unit, St John s Institute of Dermatology, St Thomas Hospital, King s College, London, UK
    J Invest Dermatol 126:1388-95. 2006
    ..These findings suggest heterogeneous abnormalities of CCND and RB in CTCL, in which dysregulated CCND and RB1 may lead to impaired cell cycle control...
  54. ncbi Antiproliferative effect of semaphorin 3F on human melanoma cell lines
    Isabelle Chabbert-de Ponnat
    J Invest Dermatol 126:2343-5. 2006
  55. ncbi [KIR3DL2: a new step for the management of patients with Sezary syndrome]
    Nicolas Ortonne
    Med Sci (Paris) 22:691-3. 2006
  56. ncbi CD56-positive haematological neoplasms of the skin: a multicentre study of the Cutaneous Lymphoma Project Group of the European Organisation for Research and Treatment of Cancer
    Chalid Assaf
    Department of Dermatology, Charite, Berlin, Germany
    J Clin Pathol 60:981-9. 2007
    ..However, prognostic subsets within the CD56+ group have been difficult to identify due to the lack of uniform clinicopathological and immunophenotypical criteria...
  57. ncbi Sezary syndrome cells unlike normal circulating T lymphocytes fail to migrate following engagement of NT1 receptor
    Marilyn Magazin
    INSERM Unit 448 and the Dermatology Department of Henri Mondor Hospital, Creteil, France
    J Invest Dermatol 122:111-8. 2004
    ..Taken together, these results, which show functional distinctions between normal circulating lymphocytes and Sezary syndrome cells, contribute to further understanding of the physiopathology of these atypical cells...
  58. ncbi Study of the reactive dendritic cells in small B-cell lymphoproliferations of the skin
    Amelie Carbonnelle
    Departement de Pathologie, Hopital Henri Mondor, VI AP HP, Universite Paris XII, Creteil, France
    Virchows Arch 450:441-7. 2007
    ..The results of our study suggest that DDC might play an important role in the genesis of cutaneous lymphomas...
  59. ncbi Killer cell Ig-like receptors CD158a and CD158b display a coactivatory function, involving the c-Jun NH2-terminal protein kinase signaling pathway, when expressed on malignant CD4+ T cells from a patient with Sezary syndrome
    Anne Marie-Cardine
    Blood 109:5064-5. 2007
  60. ncbi CD158K/KIR3DL2 transcript detection in lesional skin of patients with erythroderma is a tool for the diagnosis of Sézary syndrome
    Nicolas Ortonne
    Department of Pathology, AP HP, Groupe Hospitalier Henri Mondor Albert Chenevier, Creteil, France
    J Invest Dermatol 128:465-72. 2008
    ..0003). In light of these findings, CD158k/KIR3DL2 transcripts appear to be a unique molecular marker of SS in skin samples, allowing differential diagnosis with benign EID in routine practice...
  61. ncbi Primary cutaneous diffuse large B-cell lymphoma, leg type: clinicopathologic features and prognostic analysis in 60 cases
    Florent Grange
    Department of Dermatology, Hopital Robert Debre, avenue du Général Koenig, Reims 51100, France
    Arch Dermatol 143:1144-50. 2007
    ....
  62. ncbi Recent discoveries in the genetics of melanoma and their therapeutic implications
    Amélie Marquette
    INSERM Unit 841, IMRB, Equipe 02, 8 rue du General Sarrail, 94010, Creteil, France
    Arch Immunol Ther Exp (Warsz) 55:363-72. 2007
    ..Thus there is a need for new therapies to improve the treatment of advanced melanoma. This review provides an overview of recent discoveries in the genetics of melanoma which could offer new therapeutic opportunities...
  63. ncbi Blastic NK-cell lymphomas (agranular CD4+CD56+ hematodermic neoplasms): a review
    Tony Petrella
    Centre de Pathologie, Department of Pathology, Centre Hospitalo-Universitaire, Dijon, France
    Am J Clin Pathol 123:662-75. 2005
    ..The major clinical, histopathologic, and phenotypic aspects of the disease and diagnostic criteria and data suggesting a plasmacytoid dendritic cell origin for the tumor cells are provided...
  64. ncbi Introduction: cutaneous T-cell lymphoma (CTCL)--classification, staging, and treatment options
    Martine Bagot
    Department of Dermatology, , , France
    Dermatol Clin 26:3-12. 2008