Research Topics
| N AttalSummaryCountry: France Publications
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Publications
[The therapeutic use of D9-tetrahydrocannabinol (dronabinol) in refractory neuropathic pain]Sabine Clermont-Gnamien
Service de Pharmacie, Hopital Ambroise Pare, Boulogne, France
Presse Med 31:1840-5. 2002..All the studies used administration of cannabis alone. The aim of this open, pilot, study was to assess the efficacy and side effect profile of oral dronabinol (tetrahydrocannabinol - THC) in the treatment of refractory neuropathic pain...
[Drug treatment for neuropathic pain]Nadine Attal
INSERM U 792, F 92100 Boulogne Billancourt, France
Presse Med 37:346-53. 2008..Studies show that pregabalin, gabapentin and duloxetine have positive effects that improve quality of life, and anxiety, depressive, and sleep disorders...
Translating basic research on sodium channels in human neuropathic painNadine Attal
Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, AP HP and Université Versailles Saint Quentin, France
J Pain 7:S31-7. 2006..To date, the role of sodium channels in neuropathic pain symptoms/signs is mostly documented for mechanical static and dynamic allodynia, and either peripheral or central sodium channels may be involved...
EFNS guidelines on pharmacological treatment of neuropathic painN Attal
Centre d Evaluation at de Traitement de la Douleur, Hospital Ambroise Pare, Boulogne Billancourt, France
Eur J Neurol 13:1153-69. 2006..There are too few studies on central pain, combination therapy, and head-to-head comparison. For future trials, we recommend to assess quality of life and pain symptoms or signs with standardized tools...
[Neuropathic pain: experimental advances and clinical applications]N Attal
Centre d Evaluation et de Traitement de la Douleur et INSERM E 332 Hôpital Ambroise Paré, AP HP, Boulogne Billancourt et Université Versailles Saint Quentin
Rev Neurol (Paris) 160:199-203. 2004..Advances to date have not been spectacular although better tolerated agents have been recently marketed. Future progress should enable an appropriate response to the therapeutic challenge of neuropathic pain...
Effects of surgery on the sensory deficits of syringomyelia and predictors of outcome: a long term prospective studyN Attal
INSERM E 332, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, Boulogne Billancourt, France
J Neurol Neurosurg Psychiatry 75:1025-30. 2004..To quantify the effects of surgery on the thermal deficits of syringomyelia and assess the predictors for such effects...
EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revisionN Attal
INSERM U 987, Centre dEvaluation et de Traitement de la Douleur, Hô pital Ambroise Paré, APHP, Boulogne Billancourt, France
Eur J Neurol 17:1113-e88. 2010..This second European Federation of Neurological Societies Task Force aimed at updating the existing evidence about the pharmacological treatment of neuropathic pain since 2005...
Chronic neuropathic pain management in spinal cord injury patients. What is the efficacy of pharmacological treatments with a general mode of administration? (oral, transdermal, intravenous)N Attal
Inserm U792, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, AP HP, 9, avenue Charles de Gaulle, 92100 Boulogne Billancourt, France
Ann Phys Rehabil Med 52:124-41. 2009..The aim of this review is to present evidence for efficacy and tolerability of pharmacological treatments in SCI pain and propose therapeutic recommendations...
Assessment of spinal somatosensory systems with diffusion tensor imaging in syringomyeliaS M Hatem
Inserm U792, CHUAmbroise Paré, APHP, Boulogne Billancourt, France
J Neurol Neurosurg Psychiatry 80:1350-6. 2009....
Painful and painless peripheral sensory neuropathies due to HIV infection: a comparison using quantitative sensory evaluationD Bouhassira
Unité d évaluation et de traitement de la douleur, Hopital Ambroise Pare, Paris, France
Pain 80:265-72. 1999....
Carbamazepine in agitation and aggressive behaviour following severe closed-head injury: results of an open trialP Azouvi
Department of Neurological Rehabilitation, Raymond Poincare Hospital, Garches, France
Brain Inj 13:797-804. 1999..It is concluded that carbamazepine might help to reduce agitated behaviour in brain-injured patients. However, response to treatment demonstrated an important inter-individual variability...
Neuropathic pain: are there distinct subtypes depending on the aetiology or anatomical lesion?N Attal
INSERM U 792, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, APHP, Boulogne Billancourt, F 92100, France
Pain 138:343-53. 2008....
Painful diabetic neuropathy: diagnosis and managementA Hartemann
Service de Diabetologie, Hopital de la Pitie, AP HP, Universite Pierre et Marie Curie, 83, Boulevard de l Hopital, 75013 Paris, France
Diabetes Metab 37:377-88. 2011....
Chronic neuropathic pain: mechanisms and treatmentN Attal
Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, Boulogne, France
Clin J Pain 16:S118-30. 2000..A mechanism-based approach seems promising for clinical research studies, although its application in current management remains challenging...
Prevalence of chronic pain with neuropathic characteristics in the general populationDidier Bouhassira
INSERM U 792, Centre de Traitement et d Evaluation de la Douleur, CHU Ambroise Pare, 9, avenue Charles de Gaulle, Boulogne Billancourt cedex F 92100, France
Pain 136:380-7. 2008..We identified distinctive socio-demographic profile and clinical features indicating that chronic pain with neuropathic characteristics is a specific health problem...
Comparison of the pain suppressive effects of clinical and experimental painful conditioning stimuliDidier Bouhassira
INSERM E 332 Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, Boulogne Billancourt, France
Brain 126:1068-78. 2003..Thus, the mechanisms of counterirritation are not univocal, but depend on the pathophysiological mechanisms of clinical pain...
Botulinum toxin type A induces direct analgesic effects in chronic neuropathic painDanièle Ranoux
Services de Neurologie, Neurochirurgie et Soins Palliatifs, Centre Hospitalier Universitaire de Limoges, Limoges, France
Ann Neurol 64:274-83. 2008..Botulinum toxin type A (BTX-A) has been reported to have analgesic effects independent of its action on muscle tone, possibly by acting on neurogenic inflammation. Such a mechanism may be involved in peripheral neuropathic pain...
Mechanisms of central neuropathic pain: a combined psychophysical and fMRI study in syringomyeliaDenis Ducreux
Department of Neuroradiology, , AP-HP, , , France
Brain 129:963-76. 2006..The prefrontal cortex was the only area consistently activated by pathological evoked pains, suggesting that alteration of high-level pain modulatory mechanisms might play a major role in allodynia due to central lesion...
Development and validation of the Neuropathic Pain Symptom InventoryDidier Bouhassira
INSERM E 332, Center d Evaluation t de Traitement de la Douleur, Hôspiat Ambroise paré, Boulogne Billancourt, France
Pain 108:248-57. 2004....
Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4)Didier Bouhassira
INSERM E 332, AP HP Hôpital Ambroise Paré, Boulogne and Université Versailles Saint Quentin, France
Pain 114:29-36. 2005..The 10-item questionnaire developed in the present study constitutes a new diagnostic instrument, which might be helpful both in clinical research and daily practice...
Using screening tools to identify neuropathic painMichael I Bennett
Clinical Teaching and Research Unit, St. Gemma's Hospice, 329 Harrogate Road, Leeds LS17 6QD, UK
Pain 127:199-203. 2007
Psychophysical study of the effects of topical application of menthol in healthy volunteersSamar Hatem
INSERM, U792, CHU Ambroise Par, AP-HP, Boulogne-Billancourt F-92100, France
Pain 122:190-6. 2006..These data suggest that 30% menthol application may be a useful experimental model for studies of cold hyperalgesia in humans. The absence of local skin reactions also makes this test potentially suitable for use in patients...
Towards a new taxonomy of idiopathic orofacial painAlain Woda
EA 3847, Faculte de Chirurgie Dentaire, CHU Clermont Ferrand 63000, France
Pain 116:396-406. 2005..These data provide grounds for an evidence-based classification of idiopathic facial pain entities and indicate that the current sub-classification of these syndromes relies primarily on the topography of the symptoms...
Can pain be more or less neuropathic?Nadine Attal
Pain 112:223-4. 2004
Can pain be more or less neuropathic?Nadine Attal
Pain 110:510-1. 2004
Topical clonazepam in stomatodynia: a randomised placebo-controlled studyChristelle Gremeau-Richard
INSERM E 0216, , , CHU Clermont-Ferrand, Clermont-Ferrand 63000, France
Pain 108:51-7. 2004..It is hypothesised that clonazepam acts locally to disrupt the mechanism(s) underlying stomatodynia...
