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Genomes and Genes | Corinne AlbertiSummaryCountry: France Publications
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Publications
Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort studyCorinne Alberti
Department of Biostatistics, Saint Louis Hospital, Paris, France
Intensive Care Med 28:108-21. 2002..To examine the incidence of infections and to describe them and their outcome in intensive care unit (ICU) patients...- Improving estimates of event incidence over time in populations exposed to other events: application to three large databasesCorinne Alberti
Departement de Biostatistique et Informatique Medicale, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75475 Paris, France
J Clin Epidemiol 56:536-45. 2003..A competing-risk approach must be used to analyze the risk of events other than death in cohort studies, particularly when mortality rates are high... - Influence of systemic inflammatory response syndrome and sepsis on outcome of critically ill infected patientsCorinne Alberti
Service de Sante Publique, 48 Boulevard Serurier, 75019 Paris, France
Am J Respir Crit Care Med 168:77-84. 2003..Refinement of risk stratification of patients presenting with infection and no organ dysfunction is needed... - Systemic inflammatory response and progression to severe sepsis in critically ill infected patientsCorinne Alberti
Clinical Epidemiology Unit, , Paris, France
Am J Respir Crit Care Med 171:461-8. 2005..A score estimating this risk, using objectively defined criteria for systemic inflammatory response syndrome, could be used by physicians to stratify patients for clinical management and to test new interventions... - Cyclophosphamide in steroid-dependent nephrotic syndromeSonia Azib
Pediatric Nephrology Department, Assistance Publique Hopitaux de Paris, Universite Paris 7, Hopital Robert Debre, Paris, France
Pediatr Nephrol 26:927-32. 2011..These findings suggest that despite the wide use of new immunosuppressive agents, a short course of CPO remains an effective second-line therapy in SDNS patients. Optimal efficiency was observed in children over 7.5 years... - Impact of adverse events on outcomes in intensive care unit patientsMaite Garrouste Orgeas
Medical Surgical ICU, Saint Joseph Hospital Network, Paris, France
Crit Care Med 36:2041-7. 2008..To examine the association between predefined adverse events (AE) (including nosocomial infections) and intensive care unit (ICU) mortality, controlling for multiple adverse events in the same patient and confounding variables... - Growth in boys with idiopathic nephrotic syndrome on long-term cyclosporin and steroid treatmentValerie Leroy
Assistance Publique Hopitaux de Paris, Hopital Robert Debre, Service de Nephrologie Pediatrique, Paris, France
Pediatr Nephrol 24:2393-400. 2009..Careful monitoring of growth is recommended, given than up to 25% of patients experienced severe growth retardation during the course of their disease... - Positive impact of long-term antithyroid drug treatment on the outcome of children with Graves' disease: national long-term cohort studyJuliane Leger
Assistance Publique Hopitaux de Paris, Hopital Robert Debre, Service d endocrinologie pédiatrique, Centre de Référence des Maladies Endocriniennes Rares de la Croissance, INSERM Unité 676, Hopital Robert Debre, 48 Boulevard Serurier, 75019 Paris, France
J Clin Endocrinol Metab 97:110-9. 2012..Drug-based therapy is usually the initial treatment for Graves' disease (GD) hyperthyroidism in children, but there is some debate about treatment duration... - The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adultsFabrice Bruneel
, , , Paris, France
Am J Respir Crit Care Med 167:684-9. 2003..Severe imported malaria remains a major threat to travelers. In our population, the most relevant World Health Organization major defining criteria were coma, shock, pulmonary edema, and acidosis... - Determinants of postintensive care unit mortality: a prospective multicenter studyElie Azoulay
Medical ICU, , Paris, France
Crit Care Med 31:428-32. 2003.... - Consequences of being born small for gestational age on body composition: an 8-year follow-up studyTaly Meas
Institut National de la Santé et de la Recherche Médicale Unité 690, Hopital Robert Debre, 75019 Paris, France
J Clin Endocrinol Metab 93:3804-9. 2008..Increased fat mass has been reported in children and adults born small for gestational age (SGA). However, the progression of anthropometric parameters have been poorly documented in SGA adults... - Impact of neutropenia duration on short-term mortality in neutropenic critically ill cancer patientsMichael Darmon
Medical Intensive Care Unit, Saint Louis University Hospital and Paris 7 University, 1 avenue Claude Vellefaux, 75010 Paris, France
Intensive Care Med 28:1775-80. 2002..ICU-acquired events might be modeled as time-dependent variables in a Cox model, rather than standard covariates in logistic regression models... - Fewer infants than older patients in paediatric randomised controlled trialsFrancois Angoulvant
AP HP, Hopital Robert Debre, Université Denis Diderot Paris VII, Unité INSERM CIE5, 48 Bd Serurier, 75019, Paris, France
Eur J Epidemiol 25:593-601. 2010.... - Serum concentrations of insulin-like growth factor (IGF)-1 and IGF binding protein-3 (IGFBP-3), IGF-1/IGFBP-3 ratio, and markers of bone turnover: reference values for French children and adolescents and z-score comparability with other referencesCorinne Alberti
INSERM, CIC EC CIE5, Paris, France
Clin Chem 57:1424-35. 2011.... - Kidney transplant in black recipients: are African Europeans different from African Americans?Nicolas Pallet
, , Paris, France
Am J Transplant 5:2682-7. 2005..The results of renal transplantation in patients of African origin could be improved with universal immunosuppressive drug coverage... - Junior versus senior physicians for informing families of intensive care unit patientsDelphine Moreau
, , Paris, France
Am J Respir Crit Care Med 169:512-7. 2004..9 vs. 34.4%, p = 0.004). Specialty residents, if given opportunities for acquiring experience, can become proficient in communicating with families and share this task with senior physicians... - Aetiology and epidemiology of fever in children presenting to the emergency department of a French paediatric tertiary care centre after international travelJerome Naudin
Assistance Publique des Hopitaux de Paris, Service de Réanimation Pédiatrique, Hopital Robert Debre, Paris, France
Arch Dis Child 97:107-11. 2012..As few data are available on the causes of fever in children returning from international travel, the authors studied children presenting to a French tertiary care centre with fever... - Novel modeling of reference values of cardiovascular risk factors in children aged 7 to 20 yearsHélène Mellerio
CIC EC CIE 5, Hopital Robert Debre, 48 Boulevard Serurier, 75019 Paris, France
Pediatrics 129:e1020-9. 2012.... - Noninvitation of eligible individuals to participate in pediatric studies: a qualitative studyPhilippe Amiel
Institut Gustave Roussy, Villejuif, Unité de Recherche en Sciences Humaines et Sociales, Assistance Publique Hopitaux de Paris, Hopital Robert Debre, Paris, France
Arch Pediatr Adolesc Med 161:446-50. 2007..To identify subjective factors that lead investigators not to invite eligible individuals to participate in pediatric studies... - Addition of cyclophosphamide to steroids provides no benefit compared with steroids alone in treating adult patients with severe Henoch Schönlein PurpuraEvangeline Pillebout
Nephrology Department, Hopital Saint Louis, 1 av C Vellefaux, Paris, France
Kidney Int 78:495-502. 2010..The small population size of our study does not permit definitive conclusions; however, we suggest that treatment of adults with severe HSP by adding cyclophosphamide provides no benefit compared with steroids alone... - Microstructural development of human brain assessed in utero by diffusion tensor imagingTony Bui
Department of Paediatric Imaging, , AP-HP, 48 Boulevard Serurier, Paris 75019, France
Pediatr Radiol 36:1133-40. 2006..CONCLUSION: Diffusion tensor imaging in utero can provide a quantitative assessment of the microstructural development of fetal white matter. Anisotropic parameters of the diffusion tensor should improve with technical advances... - Pre/postbronchodilator interrupter resistance values in healthy young childrenNicole Beydon
Physiology Department, Robert Debre Teaching Hospital, Paris, France
Am J Respir Crit Care Med 165:1388-94. 2002..Sex did not affect pre- or postbronchodilator values. Data from the present study may prove useful for testing lung function in young children with respiratory disorders who failed to cooperate with forced expiratory maneuvers... - Crohn's disease: the cold chain hypothesisJean Pierre Hugot
Laboratoire de Génétique des Maladies Inflammatoires de l Intestin, Projet Avenir INSERM, Fondation Jean Dausset CEPH, Paris, France
Lancet 362:2012-5. 2003.... - Alternate-site testing is reliable in children and adolescents with type 1 diabetes, except at the forearm for hypoglycemia detectionNadine Lucidarme
Department of Endocrinology, Robert Debre Teaching Hospital, 75019 Paris, France
Diabetes Care 28:710-1. 2005 - A prospective study of the efficacy and tolerance of a chimeric antibody to tumor necrosis factors (remicade) in severe pediatric crohn diseaseJean Pierre Cezard
Pediatric Gastroenterology Unit, Hopital Robert Debre, dagger Pediatric Gastroenterology Unit, Hopital Necker Enfants Malades, and double dagger Laboratory of Coprology, Hopital Pitie Salpetriere, Paris, France
J Pediatr Gastroenterol Nutr 36:632-6. 2003..One patient received only one injection. Eighteen patients were corticosteroid dependent, and 6 were receiving parenteral nutrition. Three patients were corticoid resistant (1 mg/kg/d >15 days). Sixteen had perianal disease... - Mycophenolate mofetil for steroid-dependent nephrotic syndrome: a phase II Bayesian trialVeronique Baudouin
Assistance Publique Hopitaux de Paris, Hopital Robert Debre, Pediatric Nephrology Department, Universite Paris 7, 48 Boulevard Serurier, 75019, Paris, France
Pediatr Nephrol 27:389-96. 2012..MMF reduces relapse rate and steroid dose in children with SDNS and should be proposed before cyclosporine and cyclophosphamide... - Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndromeAnne Laure Sellier-Leclerc
Service de Nephrologie, Assistance Publique Hopitaux de Paris, Hopital Robert Debre, 48 Boulevard Serurier, 75 019 Paris, France
J Am Soc Nephrol 18:2392-400. 2007..New therapies are urgently needed, and further research should elucidate the unexplained HUS group... - Variation in serum and plasma PTH levels in second-generation assays in hemodialysis patients: a cross-sectional studyDominique Joly
Service de Nephrologie, Laboratoire d Explorations Fonctionnelles and Inserm Unit 845, Hopital Necker Enfants Malades, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
Am J Kidney Dis 51:987-95. 2008..In this cross-sectional study, we aim to determine the usefulness of standardizing blood handling for optimal interpretation of PTH in patients with chronic kidney disease... - Subtle health impairment and socioeducational attainment in young adult patients with congenital hypothyroidism diagnosed by neonatal screening: a longitudinal population-based cohort studyJuliane Leger
Pediatric Endocrinology Department, centre de référence maladies endocriniennes rares de la croissance, Institut National de la Santé et de la Recherche Médicale Unité 676, Hopital Robert Debre, 48 Bd Serurier, 75019 Paris, France
J Clin Endocrinol Metab 96:1771-82. 2011..Screening programs resulting in the early treatment of patients with congenital hypothyroidism (CH) have successfully improved neurodevelopmental outcome, but little is known about long-term health... - Nod2 mediates susceptibility to Yersinia pseudotuberculosis in miceUlrich Meinzer
INSERM, U843, Universite Paris 7, Hopital Robert Debre, Paris, France
PLoS ONE 3:e2769. 2008..This resistance phenotype was lost in case of intraperitoneal infection. We concluded that Nod2 contributes to the susceptibility to Y. pseudotuberculosis in mice... - Predictors of autoimmune hyperthyroidism relapse in children after discontinuation of antithyroid drug treatmentFlorentia Kaguelidou
Institut National de la Santé et de la Recherche Médicale U690, Hopital Robert Debre, 75019 Paris, France
J Clin Endocrinol Metab 93:3817-26. 2008..There is debate about how Graves' disease (GD) should be treated in children... - Pulmonary function tests in preschool children with cystic fibrosisNicole Beydon
, Paris, France
Am J Respir Crit Care Med 166:1099-104. 2002..04). Genotype did not influence the data. We conclude that Rint(exp) and functional residual capacity measurements may help to follow young children with CF who are unable to perform reproducible forced expiratory maneuvers... - Genotype-phenotype correlations in fetuses and neonates with autosomal recessive polycystic kidney diseaseErick Denamur
Assistance Publique Hopitaux de Paris, Universite Paris Diderot, Hopital Robert Debre, Laboratoire de Biochimie Genetique, INSERM U722, Paris, France
Kidney Int 77:350-8. 2010..Their absence, however, does not guarantee survival to the neonatal period... - Drug administration errors and their determinants in pediatric in-patientsSonia Prot
Pharmacy Unit, , Paris, France
Int J Qual Health Care 17:381-9. 2005..22; CI = 1.01-1.48). CONCLUSIONS: The risk factors identified in our study should prove useful for designing preventive strategies, thereby improving the quality of care... - Ileal involvement is age dependent in pediatric Crohn's diseaseUlrich Meinzer
Department of Paediatric Gastroenterology, , , Paris, France
Inflamm Bowel Dis 11:639-44. 2005..The rarity of small bowel lesions should be a warning to be cautious when classifying chronic colitis in small children... - Enhanced expression of the CD71 mesangial IgA1 receptor in Berger disease and Henoch-Schönlein nephritis: association between CD71 expression and IgA depositsElie Haddad
Service de Nephrologie, Service de Sante Publique, EA 3102, Université Paris 7 and Service de Pathologie, Hopital Robert Debre, Assistance Publique Hopitaux de Paris, Paris, France
J Am Soc Nephrol 14:327-37. 2003..However, the association between IgA deposits and CD71 expression and their co-localization in the mesangium provide strong evidence that CD71 is a major IgA receptor on mesangial cells... - Octogenarians reaching end-stage renal disease: cohort study of decision-making and clinical outcomesDominique Joly
Nephrology Unit, Necker Hospital and Université René Descartes Paris V, Paris, France
J Am Soc Nephrol 14:1012-21. 2003.... - Inter-observer variability in chest radiograph reading for diagnosing acute lung injury in childrenFrancois Angoulvant
Service de réanimation et surveillance continue pédiatriques, Hopital Robert Debre, Assistance Publique Hôpitaux de Paris et Université Paris Diderot Paris VII, Paris, France
Pediatr Pulmonol 43:987-91. 2008..Given the low incidence of ALI/ARDS in children, this variability may have a large impact in studies of pediatric ALI/ARDS... - Non-financial conflicts of interest in academic grant evaluation: a qualitative study of multiple stakeholders in franceHendy Abdoul
AP HP, Hopital Robert Debre, Unité d Epidémiologie Clinique, Paris, France
PLoS ONE 7:e35247. 2012..Few observational studies have assessed these issues. We report the results of a qualitative study on reviewers' and applicants' perceptions and experiences of CoIs in reviews of French academic grant applications... - HLA alleles and haplotypes in French North African immigrantsBeatrice Pedron
Laboratory of Immunology, Hopital Robert Debre, Paris, France
Hum Immunol 67:540-50. 2006..6% of the total haplotypes in North Africans but 2.4% in controls. These results thus suggest a low degree of admixture between the two populations... - Effect of transfusion therapy on cerebral vasculopathy in children with sickle-cell anemiaBrigitte Bader-Meunier
Assistance Publique Hopitaux de Paris, Service d Hématologie Pédiatrique, Hopital Necker, Paris, France
Haematologica 94:123-6. 2009..Further studies are needed to determine whether different therapeutic approaches have to be considered according to these different evolutive patterns in SS children... - Henoch-Schönlein Purpura in adults: outcome and prognostic factorsEvangeline Pillebout
INSERM U426, Faculte de Medecine X Bichat, Université Paris 07, Paris, France
J Am Soc Nephrol 13:1271-8. 2002..Identification of clinical and histologic prognostic factors may permit the design of appropriate therapeutic prospective studies... - Proficiency program for real-time PCR diagnosis of Bordetella pertussis infections in French hospital laboratories and at the French National Reference Center for Whooping Cough and other BordetellosesValerie Caro
Institut Pasteur, Centre National de Référence CNR de la Coqueluche et autres Bordetelloses, Paris, France
J Clin Microbiol 47:3197-203. 2009..However, the risk of false-positive results remains quite high, and we strongly recommend establishment of uniform quality control procedures performed regularly... - Time course of catch-up in adiposity influences adult anthropometry in individuals who were born small for gestational ageNadia Ezzahir
INSERM U457, , 75019 Paris, France
Pediatr Res 58:243-7. 2005..Whether this observation holds through regarding the metabolic syndrome remains to be elucidated... - Clinical outcome of cystic fibrosis presenting with or without meconium ileus: a matched cohort studyAnne Munck
Cystic Fibrosis Centre, Hospital Robert Debré 48, bd Serurier, 75019 Paris, France
J Pediatr Surg 41:1556-60. 2006..This matched case-control study compared the nutritional and the pulmonary long-term outcomes of cystic fibrosis (CF) patients presenting a history of meconium ileus (MI) with early-diagnosed symptomatic CF without MI (non-MI)... - Lower bone mineral content in children with type 1 diabetes mellitus is linked to female sex, low insulin-like growth factor type I levels, and high insulin requirementJuliane Leger
Pediatric Endocrinology Unit and INSERM U 690, Hopital Robert Debre, 48 Boulevard Serurier, 75019 Paris, France
J Clin Endocrinol Metab 91:3947-53. 2006..Studies on bone mineral characteristics in children with type 1 diabetes mellitus (T1DM) have generated conflicting results... - The spectrum of cardiac anomalies in Noonan syndrome as a result of mutations in the PTPN11 geneYves Sznajer
Department of Medical Genetics, AP HP Robert DEBRE University Hospital, Paris, France
Pediatrics 119:e1325-31. 2007..quot; We report the heart defects and links to gene dysfunction in cardiac development in a large cohort of patients with type 1 Noonan syndrome... - Improvement in bone mineral density and body composition in survivors of childhood acute lymphoblastic leukemia: a 1-year prospective studyDaniela Marinovic
, Paris, France
Pediatrics 116:e102-8. 2005..These findings suggest a positive effect of long-term completion therapy and increase in physical activity on BMD, body composition, and bone metabolism in patients who have been treated for ALL... - Tracheostomy does not improve the outcome of patients requiring prolonged mechanical ventilation: a propensity analysisChristophe Clec'h
Intensive Care Unit, Avicenne Teaching Hospital, 125 route de Stalingrad, 93000 Bobigny, France
Crit Care Med 35:132-8. 2007..To examine the association between the performance of a tracheostomy and intensive care unit and postintensive care unit mortality, controlling for treatment selection bias and confounding variables... - Pulmonary function tests in preschool children with asthmaNicole Beydon
, Grenoble, France
Am J Respir Crit Care Med 168:640-4. 2003..Pulmonary function tests that do not require active cooperation may help in the management and follow-up of preschool children with asthma who are unable to perform forced expiratory maneuvers... - Epidemiology and economic evaluation of severe sepsis in France: age, severity, infection site, and place of acquisition (community, hospital, or intensive care unit) as determinants of workload and costChristophe Adrie
Medical-Surgical ICU, Delafontaine Hospital, Saint Denis, France
J Crit Care 20:46-58. 2005..CONCLUSIONS: The wide variations in cost and workload invite efforts to identify patient subgroups most likely to benefit from high-cost treatments and from prevention, particularly targeting severe nosocomial infections... - Post-ICU mortality in critically ill infected patients: an international studyElie Azoulay
Intensive Care Unit, Saint-Louis Hospital, Paris 7 University, 1 Avenue Claude, Vellefaux, 75010 Paris, France
Intensive Care Med 31:56-63. 2005..Further interventions such as further ICU management, discharge to a step-down unit, or follow-up by intensivists on the ward should be evaluated in patients with a high risk of post-ICU mortality... - [Epidemiology of infection and sepsis in intensive care unit patients]Jean Roger Le Gall
, , 1 avenue Claude Vellefaux 75010 Paris
Bull Acad Natl Med 188:1115-25; discussion 1125-6. 2004..Crude incidence rates of ICU infection were high, varying among ICUs and patient subsets. Thus, vital outcome depends not only on the severity of sepsis but also on the characteristics of the infection... - The relationship between the GH/IGF-I axis and serum markers of bone turnover metabolism in healthy childrenJuliane Leger
Pediatric Endocrinology Department, Centre de Référence des Maladies Endocriniennes Rares de la Croissance and INSERM Unit 690, Assistance Publique Hopitaux de Paris, Universite Paris VII, Robert Debre Hospital, France
Eur J Endocrinol 157:685-92. 2007..There is evidence to suggest that IGF-I plays a role in regulating bone turnover... - Pneumothorax in the intensive care unit: incidence, risk factors, and outcomeArnaud de Lassence
Medical Intensive Care Unit, , Louis Mourier Teaching Hospital, Colombes, France
Anesthesiology 104:5-13. 2006..6 (95% CI, 1.3-4.9; P = 0.004). CONCLUSION: Iatrogenic pneumothorax is a life-threatening complication seen in 3% of ICU patients. Incorporating risk factors for IP into preventive strategies should reduce the occurrence of IP... - Nosocomial infection and multidrug-resistant bacteria surveillance in intensive care units: a survey in FranceCorinne Alberti
C-CLIN Paris Nord, Paris VI University
Infect Control Hosp Epidemiol 26:13-20. 2005..CONCLUSION: This study revealed profound differences in NI surveillance strategies across ICUs, indicating a need for caution when using NI surveillance data for comparisons and benchmarking... - ICUs: from performance appraisal to executive dashboard?Corinne Alberti
Intensive Care Med 33:1313-5. 2007 - High-dose plasma infusion versus plasma exchange as early treatment of thrombotic thrombocytopenic purpura/hemolytic-uremic syndromePaul Coppo
Laboratoire Hématopoïèse et Cellules souches, Institut Gustave Roussy, Villejuif, France
Medicine (Baltimore) 82:27-38. 2003..However, the large volumes of plasma required to reach complete remission may result in fluid overload, which may necessitate subsequent therapeutic plasma exchange... - [Comparative study of hospital costs associated with human albumin 20% (Vialebex 20%) or polygeline as a fluid resuscitation strategy for cirrhotic ascites]Isabelle Durand-Zaleski
Santé Publique, Hopital Henri Mondor, Créteil 94
Presse Med 36:867-73. 2007..To compare the hospital costs associated with two fluid resuscitation strategies for cirrhotic ascites: one with human albumin 20% (Vialebex 20%) and one with polygeline... - Impact of unplanned extubation and reintubation after weaning on nosocomial pneumonia risk in the intensive care unit: a prospective multicenter studyArnaud de Lassence
Medical ICU, Avicenne Hospital, Bobigny, France
Anesthesiology 97:148-56. 2002....