The descriptive epidemiology of obsessive-compulsive disorderLeonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro IPUB UFRJ, Rio de Janeiro, Brazil
Prog Neuropsychopharmacol Biol Psychiatry 30:327-37. 2006
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- Asperger Syndrome, obsessive-compulsive disorder, and major depression in a patient with 45,X/46,XY mosaicism
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry of the Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Psychopathology 37:105-9. 2004
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- Citalopram plus reboxetine in treatment-resistant obsessive-compulsive disorder
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry of the Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
World J Biol Psychiatry 6:57-9. 2005
..This report suggests that future studies accessing the efficacy of the SRI SNRI combination in treatment resistant OCD are needed...
- Impulse control disorders in patients with obsessive-compulsive disorder
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry of the Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Psychiatry Clin Neurosci 59:30-7. 2005
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- Sexual function and dysfunction in Brazilian patients with obsessive-compulsive disorder and social anxiety disorder
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal of Rio de Janeiro, Rio de Janeiro, Brazil
J Nerv Ment Dis 195:254-7. 2007
..Male patients with SAD reported not using contraceptive methods significantly more frequently than male patients with OCD (p = 0.007). Patients with OCD and patients with SAD exhibit different profiles of sexual behavior...
- Quality of life and symptom dimensions of patients with obsessive-compulsive disorder
Isabela S Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal do Rio de Janeiro IPUB UFRJ, Rio de Janeiro, Brazil
Psychiatry Res 179:198-203. 2010
..The severity of depressive and anxiety symptoms seems, therefore, to be powerful determinants of the level of quality of life in patients with OCD...
- The Brazilian Portuguese version of the Saving Inventory-Revised: internal consistency, test-retest reliability, and validity of a questionnaire to assess hoarding
Isabela S Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro IP UFRJ, Brazil
Psychol Rep 106:279-96. 2010
..The Saving Inventory-Revised total scores also correlated significantly with comorbid anxiety and depressive symptoms...
- Patients with obsessive-compulsive disorder and hoarding symptoms: a distinctive clinical subtype?
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry of the Federal University of Rio de Janiero, Brazil
Compr Psychiatry 45:375-83. 2004
..It remains to be investigated whether these phenotypical characteristics are underlined by specific neurobiological mechanisms...
- Obsessive-compulsive symptoms among patients with blepharospasm and hemifacial spasm
Leonardo F Fontenelle
Programa de Ansiedade e Depressao, Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro IPUB UFRJ, Rio de Janeiro, Brazil
Gen Hosp Psychiatry 33:476-81. 2011
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- Clinical subtypes of obsessive-compulsive disorder based on the presence of checking and washing compulsions
Leonardo F Fontenelle
Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Rev Bras Psiquiatr 27:201-7. 2005
..We aimed at examining the utility of checking and washing compulsions as markers of valid subtypes of obsessive-compulsive disorder (OCD)...
- Empathy and symptoms dimensions of patients with obsessive-compulsive disorder
Leonardo F Fontenelle
Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
J Psychiatr Res 43:455-63. 2009
..Our findings suggest that hoarding is linked to specific aspects of interpersonal reactivity. Comorbid depression and anxiety, however, explain a large proportion of the empathic profile exhibited by patients with OCD...
- Psychiatric comorbidity in a Brazilian sample of patients with binge-eating disorder
Leonardo F Fontenelle
The Obesity and Eating Disorders Group, State Institute of Diabetes and Endocrinology of Rio de Janeiro and Institute of Psychiatry, Federal University of Rio de Janeiro IPUB UFRJ, Rio de Janeiro, Brazil
Psychiatry Res 119:189-94. 2003
..Similar to patients from developed countries, Brazilian patients with BED display increased rates of psychiatric comorbidity, particularly mood and anxiety disorders...
- An update on the pharmacological treatment of obsessive-compulsive disorder
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal of Rio de Janeiro IPUB UFRJ, Icarai, Niteroi, RJ, Brazil
Expert Opin Pharmacother 8:563-83. 2007
..Independent studies are urgently needed to help identify the most promising drug treatment sequences for OCD...
- Catatonia in obsessive-compulsive disorder: etiopathogenesis, differential diagnosis, and clinical management
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal of Rio de Janeiro IPUB UFRJ, Rio de Janeiro, Brazil
Cogn Behav Neurol 20:21-4. 2007
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- [Treatment-resistant anxiety disorders: social phobia, generalized anxiety disorder and panic disorder]
Gabriela Bezerra de Menezes
Programa de Ansiedade e Depressao, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Rev Bras Psiquiatr 29:S55-60. 2007
..The objective of this study is to review aspects related to treatment resistance and pharmacological strategies to deal with anxiety disorders resistant to treatment...
- [Cognitive-behavior therapy for obsessive-compulsive disorder: a systematic review of the last decade]
Angélica Marques Prazeres
Programa de Pesquisa em Ansiedade e Depressão, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Rev Bras Psiquiatr 29:262-70. 2007
..To perform a systematic review of controlled trials and meta-analysis that involved cognitive and/or behavioral treatment for obsessive-compulsive disorder...
- History of trauma and dissociative symptoms among patients with obsessive-compulsive disorder and social anxiety disorder
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry of the Universidade Federal do Rio de Janeiro IPUB UFRJ, Rua Otávio Carneiro, 93 601 Rio de Janeiro, RJ, Brazil
Psychiatr Q 78:241-50. 2007
..Patients with OCD are probably less vulnerable to some types of traumatic experiences. Dissociative symptoms may cut across different anxiety disorders...
- Auditory, visual, tactile, olfactory, and bodily hallucinations in patients with obsessive-compulsive disorder
Leonardo F Fontenelle
Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
CNS Spectr 13:125-30. 2008
..Further psychopathological research should clarify the clinical significance of hallucinations among patients with OCD...
- Second-generation antidepressants in social anxiety disorder: meta-analysis of controlled clinical trials
Gabriela Bezerra de Menezes
Programa de Ansiedade e Depressao, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro IPUB UFRJ, Niteroi, Rio de Janeiro, Brazil
Psychopharmacology (Berl) 215:1-11. 2011
..A growing number of controlled clinical trials suggest that different second-generation antidepressants (SGA) may be effective in the treatment of social anxiety disorder (SAD)...
- Dementia developing in late-onset and treatment-refractory obsessive-compulsive disorder
Ilana Frydman
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal of Rio de Janeiro, Ipanema, Rio de Janeiro, RJ, Brazil
Cogn Behav Neurol 23:205-8. 2010
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- Early- and late-onset obsessive-compulsive disorder in adult patients: an exploratory clinical and therapeutic study
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry of the Federal University of Rio de Janeiro IPUB UFRJ, Brazil
J Psychiatr Res 37:127-33. 2003
..However, no significant differences between groups were noted in the final treatment outcome. Our results are consistent with previous studies suggesting that EOCD may represent a more severe subtype of this disorder...
- Absence of dementia in late-onset schizophrenia: a one year follow-up of a Brazilian case series
Jerson Laks
Center for Alzheimer s Disease and Related Disorders, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Arq Neuropsiquiatr 64:946-9. 2006
..Cognitive deficits of late-onset schizophrenia (LOS) patients have been reported as stable, although some prospective studies show that a sub-group develop a significant cognitive decline. Data on LOS from developing countries are scarce...
- Volitional disorders: a proposal for DSM-V
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal do Rio de Janeiro IPUB UFRJ, Rio de Janeiro, RJ, Brazil
World J Biol Psychiatry 10:1016-29. 2009
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- The problem of delusional ugliness: is it really body dysmorphic disorder?
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
World J Biol Psychiatry 7:110-5. 2006
..Future studies are urgently needed in order to substantiate our judgement regarding the existence of diagnostic limits between delusional BDD and DDST with dysmorphic delusions...
- [Antipsychotics, anticonvulsants, antiadrenergics and other drugs: what to do when posttraumatic stress disorder does not respond to selective serotonin reuptake inhibitors?]
William Berger
Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Rev Bras Psiquiatr 29:S61-5. 2007
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- A review on predictors of treatment outcome in social anxiety disorder
Sara Costa Cabral Mululo
Programa de Pesquisa em Ansiedade e Depressão, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Rev Bras Psiquiatr 34:92-100. 2012
..This article aims to review the clinical features and therapeutic characteristics that may predict treatment response in patients with social anxiety disorder (SAD)...
- The analytical epidemiology of obsessive-compulsive disorder: risk factors and correlates
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ, Brazil
Prog Neuropsychopharmacol Biol Psychiatry 32:1-15. 2008
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- Pareidolias in obsessive-compulsive disorder: neglected symptoms that may respond to serotonin reuptake inhibitors
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal do Rio de Janeiro IPUB UFRJ, Rio de Janeiro RJ, Brazil
Neurocase 14:414-8. 2008
..We describe a patient with OCD whose main complaint was the experience of pareidolias (i.e., 'images seen out of shapes'), a symptom that responded to treatment with a serotonin reuptake inhibitor...
- Short-lived response of cervical dystonia to electroconvulsive therapy
Rafael F Garcia
Institute of Psychiatry, Universidade Federal do Rio de Janeiro IPUB UFRJ, Rio de Janeiro, Brazil
J ECT 25:135-6. 2009
..The effectiveness of ECT for CD, although too brief to be recommended as a useful treatment, may shed light on the pathophysiology of this problematic movement disorder...
- The Wernicke-Kleist-Leonhard "short-circuiting": a missing link between attention deficit hyperactivity disorder, Tourette syndrome, and obsessive-compulsive disorder?
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ, Brazil
Med Hypotheses 71:418-25. 2008
..A resurgence of the interest on the descriptive psychopathology of the WKL short-circuit movements could provide a new conceptual framework for the studies on the neurobiology of volitional disorders...
- Towards a post-traumatic subtype of obsessive-compulsive disorder
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro, Brazil
J Anxiety Disord 26:377-83. 2012
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- Comparison of symptom profiles of obese binge eaters, obese non-binge eaters, and patients with obsessive-compulsive disorder
Leonardo F Fontenelle
Anxiety and Depression Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro (IPUB/UFRJ, Rio de Janeiro, Brazil
J Nerv Ment Dis 190:643-6. 2002
- Management of obsessive-compulsive disorder with fluvoxamine extended release
Lidia Ordacgi
Anxiety and Depression Research Program, Institute of Psychiatry, Universidade Federal do Rio de Janeiro IPUB UFRJ, Rio de Janeiro, Brazil
Neuropsychiatr Dis Treat 5:301-8. 2009
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- Clinical features associated to refractory obsessive-compulsive disorder
Ygor A Ferrão
Department of Psychiatry, University of Sao Paulo Medical School, Sao Paulo, Brazil
J Affect Disord 94:199-209. 2006
..The clinical variables associated with treatment-refractoriness in OCD are inconsistently described in the literature...
- A sociodemographic, phenomenological, and long-term follow-up study of patients with body dysmorphic disorder in Brazil
Leonardo F Fontenelle
Federal University of Rio de Janeiro, Brazil
Int J Psychiatry Med 36:243-59. 2006
..In this non-controlled study, our objective was to describe the socio-demographic, phenomenological, and long-term outcome features of a Brazilian sample of patients with BDD...
- Treatment-response by age at onset in obsessive-compulsive disorder
Leonardo F Fontenelle
J Affect Disord 83:283-4. 2004
- Trans-cultural aspects of obsessive-compulsive disorder: a description of a Brazilian sample and a systematic review of international clinical studies
Leonardo F Fontenelle
The Anxiety and Depression Research Program, Institute of Psychiatry of the Federal University of Rio de Janeiro IPUB UFRJ, Rupa Lopes Trovão, 88, apt, 1501, Bloco A, Icarai, Niteroi, RJ, CEP 24220 071, Brazil
J Psychiatr Res 38:403-11. 2004
..The core features of OCD are probably relatively independent of cultural variations. The sole exception to this rule seems to be the content of the obsessions, in which cultural factors may play a significant role...
- An open-label trial of sibutramine in obese patients with binge-eating disorder
Jose C Appolinario
Obesity and Eating Disorders Group, Institute of Psychiatry, Federal University of Rio de Janeiro, Brazil
J Clin Psychiatry 63:28-30. 2002
..The objective of this article is to present data from an open-label study of the efficacy and tolerability of sibutramine in a group of obese binge eaters...
- Patients with obsessive-compulsive disorder (OCD) displayed cognitive deficits consistent with a dysfunction of the dorsolateral-striatal circuit
Leonardo F Fontenelle
Psychol Med 34:181; author reply 181-3. 2004
- Patients with obsessive-compulsive disorder (OCD) displayed cognitive deficits consistent with a dysfunction of the dorsolateral-striatal circuit
Leonardo F Fontenelle
Psychol Med 34:1367-8; author reply 1368-9. 2004
- Low-resolution electromagnetic tomography and treatment response in obsessive-compulsive disorder
Leonardo F Fontenelle
Anxiety and Depression Research Programme, Institute of Psychiatry of the Federal University of Rio de Janeiro IPUB UFRJ, Brazil
Int J Neuropsychopharmacol 9:89-94. 2006
..002) and the medial frontal gyrus (BA 10) (p = 0.002), suggesting that a distinctive pattern of activity within the medial surface of the frontal lobe predicts therapeutic response in OCD...
- Obsessions with aggressive content emerging during the course of panic disorder: a different subtype of obsessive-compulsive disorder?
Leonardo F Fontenelle
Institute of Psychiatry of the Federal University of Rio de Janeiro IPUB UFRJ, Icaraí Niterói RJ, Brazil
Int Clin Psychopharmacol 20:343-6. 2005
..Our cases suggest that patients with OCD should be probed for an underlying panic disorder. This 'panic disorder-related subtype of OCD' may be associated with an excellent treatment response and increased rates of remission...
- Antibasal ganglia antibodies, immunomodulation, and antibiotics in "poststreptococcal" adult neuropsychiatric disorders: not yet ready for "prime time"
Antonio L Teixeira
Cogn Behav Neurol 21:124-5. 2008
- Topiramate may modulate alcohol abuse but not other compulsive behaviors in frontotemporal dementia: case report
Marcelo Cruz
Drug Abuse Research and Assistance Program, Institute of Psychiatry, Federal University of Rio de Janeiro, RJ, Brazil
Cogn Behav Neurol 21:104-6. 2008
..On the basis of the mechanism of action of topiramate, we discuss the possible specificity of action of topiramate to control abusive drinking, but not to treat other clinical symptoms of FTD...
- Diogenes syndrome in a patient with obsessive-compulsive disorder without hoarding
Leonardo F Fontenelle
Department of Psychiatry and Mental Health, Universidade Federal Fluminense MSM UFF, Niteroi, RJ, Brazil
Gen Hosp Psychiatry 30:288-90. 2008
..We suggest that hoarding may be a symptom of the conditions that are frequently comorbid with DS, but is not one of its fundamental features...
- Treatment of juvenile Parkinson disease and the recurrent emergence of pathologic gambling
Rafael Ferreira Garcia
Programa de Ansiedade e Depressão do Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro IPUB UFRJ, Brazil
Cogn Behav Neurol 20:11-4. 2007
..To describe the recurrent emergence of pathologic gambling (PG) during the sequential treatment of a patient with Juvenile Parkinson disease (PD) with different dopamine agonists...
- Treatment-resistant self-mutilation, tics, and obsessive-compulsive disorder in neuroacanthocytosis: a mouth guard as a therapeutic approach
Leonardo F Fontenelle
J Clin Psychiatry 69:1186-7. 2008
