Research Topics
Species | Anne TammimäkiSummaryAffiliation: University of Helsinki Country: Finland Publications
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Detail Information
Publications
Effect of forced chronic oral nicotine exposure on intravenous self-administration and rewarding properties of acute nicotineAnne Tammimäki
Division of Pharmacology and Toxicology, Faculty of Pharmacy, University of Helsinki, Finland
Eur J Pharmacol 591:164-70. 2008..In conclusion, these results suggest that nicotine pre-exposure enhances the reinforcing effects of acutely administered nicotine only in the intravenous self-administration model...
Increase in free choice oral ethanol self-administration in catechol-o-methyltransferase gene-disrupted male miceAnne Tammimäki
Division of Pharmacology and Toxicology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland
Basic Clin Pharmacol Toxicol 103:297-304. 2008....
Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in miceAnne Tammimäki
Division of Pharmacology and Toxicology, Faculty of Pharmacy, University of Helsinki, P O Box 56, 00014, Helsinki, Finland
Psychopharmacology (Berl) 211:389-401. 2010..Our aims were to assess the behavioral phenotype of S-COMT mutant mice and to clarify the role of MB-COMT in dopamine metabolism in different brain areas...
Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving miceMikko Käenmäki
Division of Pharmacology and Toxicology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland
J Neurochem 114:1745-55. 2010..Inhibition of DAT had no effect on DA levels in either genotype. Therefore, we conclude that in the mouse, PFC COMT contributes about one half of the total DA clearance...
