Research Topics
Species | Craig M StolenSummaryAffiliation: University of Turku Country: Finland Publications
Research Grants
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Detail Information
Publications
Semicarbazide sensitive amine oxidase overexpression has dual consequences: insulin mimicry and diabetes-like complicationsCraig M Stolen
MediCity Research Laboratory, University of Turku and National Public Health Institute, Turku, Finland
FASEB J 18:702-4. 2004..These findings suggest that, although manipulation of VAP-1/SSAO has potential to serve as a therapeutic treatment in insulin-resistant conditions, care must be taken to fully understand its impact on obesity and vascular damage...
Origins of serum semicarbazide-sensitive amine oxidaseCraig M Stolen
MediCity Research Laboratory, University of Turku and National Public Health Institute, Tykistokatu 6A, FIN 20520, Turku, Finland
Circ Res 95:50-7. 2004..An increased endothelial cell capacity for lymphocyte binding and altered expression of redox-sensitive proteins was also associated with the mTIEhVAP-1 transgene...
Absence of the endothelial oxidase AOC3 leads to abnormal leukocyte traffic in vivoCraig M Stolen
Department of Medical Microbiology, MediCity Research Laboratory, National Public Health Institute, Turku University, 20520 Turku, Finland
Immunity 22:105-15. 2005....
Function-blocking antibodies to human vascular adhesion protein-1: a potential anti-inflammatory therapyChristopher M Kirton
Immunology Division, Department of Pathology, Cambridge University, Cambridge, UK
Eur J Immunol 35:3119-30. 2005..Furthermore, the chimeric antibodies prevented leukocyte adhesion and transmigration in vitro and in vivo. Hence, these chimeric antibodies have the potential to be used as a new anti-inflammatory therapy...
Research Grants
- MANIPULATING VAP-1 EXPRESSION: VASCULAR PATHOLOGY MODELSCraig Stolen; Fiscal Year: 2003..Using these mouse models, the release of soluble VAP-1 will also be investigated. Together with specific inhibitors of VAP-1, these mice will be used as models to aid in the assessment of various vascular pathology treatment modalities...
