Research Topics
Species | Raili S RiikonenSummaryAffiliation: University of Kuopio Country: Finland Publications
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Detail Information
Publications
Insulin-like growth factor delivery across the blood-brain barrier. Potential use of IGF-1 as a drug in child neurologyRaili Riikonen
Children s Hospital, University of Kuopio, Kuopio, Finland
Chemotherapy 52:279-81. 2006..It is antiapoptotic and is important for synaptic development. The aim of this study was to identify neurological conditions with low CNS IGF-1...
Cerebrospinal fluid insulin-like growth factor 1 is low in acute and chronic white-matter diseases of childrenRaili Riikonen
Department of Child Neurology, Children s Hospital, Kuopio University Hospital, Kuopio, Finland
J Child Neurol 20:181-4. 2005..0005). Low cerebrospinal fluid insulin-like growth factor 1 can play a role in the pathology of both acute and chronic white-matter diseases of children...
Levels of cerebrospinal fluid nerve-growth factor differ in infantile autism and Rett syndromeR Riikonen
Department of Child Neurology, Children s Hospital, University of Kuopio, Finland
Dev Med Child Neurol 41:148-52. 1999..CSF NGF could be used as a biochemical marker for differentiation of patients with autism from those with RS...
Childhood convulsive status epilepticusRaili Riikonen
Department of Child Neurology, Children's Hospital, University of Kuopio, 70211 Kuopio, Finland
Lancet 368:184-5. 2006
Deep serotonergic and dopaminergic structures in fetal alcoholic syndrome: a study with nor-beta-CIT-single-photon emission computed tomography and magnetic resonance imaging volumetryRaili S Riikonen
Department of Child Neurology, Kuopio University Hospital, Kuopio, Finland
Biol Psychiatry 57:1565-72. 2005..In prenatally alcohol exposed children, the relationship between brain structure and function is highlighted to be important to study...
The latest on infantile spasmsRaili Riikonen
Children s Hospital, University of Kuopio, Finland
Curr Opin Neurol 18:91-5. 2005....
Neurotrophic factors in the pathogenesis of Rett syndromeRaili Riikonen
Department of Child Neurology, The Children s Hospital, University of Kuopio, Kuopio, Finland
J Child Neurol 18:693-7. 2003..Cholinergic gene expression might be influenced by the Rett syndrome gene directly or via the neurotrophic factor system...
The PEHO syndromeR Riikonen
Department of Child Neurology, University Hospital, P O Box 1777, Kuopio 70211, Finland
Brain Dev 23:765-9. 2001..These are the first biochemical abnormalities found in the PEHO syndrome and their study may lead to a better understanding of this devasting disease...
ACTH therapy of West syndrome: Finnish viewsR Riikonen
Department of Child Neurology, Kuopio University, Hospital, P O B 1777, Kuopio 70211, Finland
Brain Dev 23:642-6. 2001..ACTH should be used as the first choice for treatment of West syndrome (at the minimal effective dose and for shortest effective time). The side effects of steroids, unlike VGB, are well known, treatable, and reversible...
Epidemiological data of West syndrome in FinlandR Riikonen
Department of Child Neurology, Kuopio University Hospital, P O Box 1777, Kuopio 70211, Finland
Brain Dev 23:539-41. 2001..Little can be done to reduce the incidence of WS, but every effort should be made to reduce the number of SGA infants by good prenatal care and treating neonatal hypoglycemia carefully...
Low insulin-like growth factor (IGF-1) in the cerebrospinal fluid of children with progressive encephalopathy, hypsarrhythmia, and optic atrophy (PEHO) syndrome and cerebellar degenerationR Riikonen
Department of Child Neurology, Children s Hospital, University of Kuopio, Finland
Epilepsia 40:1642-8. 1999..Because insulin-like growth factor (IGF)-1 has been shown significantly to promote survival of cerebellar neurons, we wanted to see if the IGF system played a role in the pathogenesis of cerebellar atrophy...
Insulin-like growth factor-1 is associated with cognitive outcome in infantile spasmsRaili S Riikonen
University of Kuopio and Kuopio University Hospital, Kuopio, Finland
Epilepsia 51:1283-9. 2010..The aim of the present study was to correlate cerebrospinal fluid (CSF) levels of IGF-1 with antecedent insults and cognitive outcome...
Infantile spasms: therapy and outcomeRaili Riikonen
Department of Child Neurology, Children s Hospital, University of Kuopio, Kuopio, Finland
J Child Neurol 19:401-4. 2004..The frequency of visual field defects after vigabatrin therapy should be evaluated...
Favourable prognostic factors with infantile spasmsRaili S Riikonen
Kuopio University Hospital, Kuopio, P O Box 1627, FI 70211 Kuopio, Finland
Eur J Paediatr Neurol 14:13-8. 2010..As of yet there is no method to examine the visual fields in patients with infantile spasms. Early treatment of infantile spasms seems to be important. Prevention of infantile spasms with some aetiological groups might be possible...
Cerebrospinal fluid insulin-like growth factor (IGF-1) and insulin-like growth factor binding protein (IGFBP-2) in children with acute lymphoblastic leukemiaRaili Riikonen
Children s Hospital, University of Kuopio, Finland
Pediatr Blood Cancer 43:110-4. 2004..We studied the levels of CSF IGF-1 and IGF binding protein-2 (IGFBP-2) in children with ALL to find out whether these levels correlated with any of the neurological deficits observed...
Cerebrospinal fluid insulin-like growth factors IGF-1 and IGF-2 in infantile autismRaili Riikonen
Department of Child Neurology, Kuopio University Central Hospital, Kuopio, Finland
Dev Med Child Neurol 48:751-5. 2006..The head growth might be explained by the actions of IGF-1 and -2 reflected in CSF concentrations...
Serotonin and dopamine transporter binding in children with autism determined by SPECTIsmo Makkonen
Department of Paediatrics, Unit of Child Neurology, Kuopio University Hospital, Kuopio, Finland
Dev Med Child Neurol 50:593-7. 2008..The low SERT binding reported here and the low serotonin synthesis capacity shown elsewhere may indicate maturation of a lesser number of serotonergic nerve terminals in individuals with autism...
Neurocognitive functioning in children with type-1 diabetes with and without episodes of severe hypoglycaemiaRiitta Hannonen
Department of Child Neurology, Kymenlaakso Central Hospital, Kotka, Finland
Dev Med Child Neurol 45:262-8. 2003..Significant differences were found in verbal short-term memory and phonological processing. Results suggest that severe hypoglycaemia is a risk factor for learning due to deficits in auditory-verbal functioning...
Verbal and academic skills in children with early-onset type 1 diabetesRiitta Hannonen
Department of Child Neurology, Kymenlaakso Central Hospital, Kotkantie 41, Kotka, Finland
Dev Med Child Neurol 52:e143-7. 2010..In addition, the incidence of dyslexia (< or =10th centile in reading speed or reading-spelling accuracy) was studied...
