J Pihlajamaki

Summary

Affiliation: University of Kuopio
Country: Finland

Publications

  1. ncbi The Pro12Ala polymorphism of the PPAR gamma 2 gene regulates weight from birth to adulthood
    Jussi Pihlajamaki
    Department of Medicine, University of Kuopio, Kuopio, Finland
    Obes Res 12:187-90. 2004
  2. ncbi A major gene effect on fasting insulin and insulin sensitivity in familial combined hyperlipidemia
    J Pihlajamaki
    Department of Medicine, University of Kuopio, Kuopio, Finland
    Diabetes 50:2396-401. 2001
  3. ncbi Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men
    Jussi Pihlajamaki
    Department of Medicine, University of Kuopio, Kuopio, Finland
    J Lipid Res 45:507-12. 2004
  4. ncbi Haplotypes of PPARGC1A are associated with glucose tolerance, body mass index and insulin sensitivity in offspring of patients with type 2 diabetes
    J Pihlajamaki
    Department of Medicine, University of Kuopio, P O Box 1627, 70210, Kuopio, Finland
    Diabetologia 48:1331-4. 2005
  5. ncbi Apolipoprotein E gene promoter (-219G/T) polymorphism is associated with premature coronary heart disease
    L Viitanen
    Department of Medicine, University of Kuopio, 70210 Kuopio, Finland
    J Mol Med (Berl) 79:732-7. 2001
  6. ncbi Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes
    J Pihlajamaki
    University of Kuopio, Department of Medicine, Kuopio, Finland
    Diabetologia 49:1560-6. 2006
  7. ncbi Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study
    O Laukkanen
    Department of Medicine, University of Kuopio, Finland
    Diabetologia 47:871-7. 2004
  8. ncbi Codon 54 polymorphism of the human intestinal fatty acid binding protein 2 gene is associated with dyslipidemias but not with insulin resistance in patients with familial combined hyperlipidemia
    J Pihlajamaki
    Department of Medicine, University of Kuopio, Finland
    Arterioscler Thromb Vasc Biol 17:1039-44. 1997
  9. ncbi Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men
    J Vangipurapu
    Department of Medicine, University of Eastern Finland, Kuopio University Hospital, 70210, Kuopio, Finland
    Diabetologia 54:563-71. 2011
  10. ncbi Diverse associations of 25-hydroxyvitamin D and 1,25-dihydroxy-vitamin D with dyslipidaemias
    P Karhapaa
    Department of Medicine, University of Eastern Finland, Kuopio, Finland
    J Intern Med 268:604-10. 2010

Collaborators

Detail Information

Publications11

  1. ncbi The Pro12Ala polymorphism of the PPAR gamma 2 gene regulates weight from birth to adulthood
    Jussi Pihlajamaki
    Department of Medicine, University of Kuopio, Kuopio, Finland
    Obes Res 12:187-90. 2004
    ..In this study, the effect of the Pro12Ala polymorphism on long-term changes in weight and body composition was investigated...
  2. ncbi A major gene effect on fasting insulin and insulin sensitivity in familial combined hyperlipidemia
    J Pihlajamaki
    Department of Medicine, University of Kuopio, Kuopio, Finland
    Diabetes 50:2396-401. 2001
    ..001). These results provide evidence for a major gene regulating insulin sensitivity in FCHL families. Possible pleiotropic effects of this insulin sensitivity locus on dyslipidemias in FCHL remain to be elucidated...
  3. ncbi Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men
    Jussi Pihlajamaki
    Department of Medicine, University of Kuopio, Kuopio, Finland
    J Lipid Res 45:507-12. 2004
    ....
  4. ncbi Haplotypes of PPARGC1A are associated with glucose tolerance, body mass index and insulin sensitivity in offspring of patients with type 2 diabetes
    J Pihlajamaki
    Department of Medicine, University of Kuopio, P O Box 1627, 70210, Kuopio, Finland
    Diabetologia 48:1331-4. 2005
    ..Therefore, we investigated the effects of single nucleotide polymorphisms in PPARGC1A on body composition and glucose tolerance and on insulin sensitivity and secretion...
  5. ncbi Apolipoprotein E gene promoter (-219G/T) polymorphism is associated with premature coronary heart disease
    L Viitanen
    Department of Medicine, University of Kuopio, 70210 Kuopio, Finland
    J Mol Med (Berl) 79:732-7. 2001
    ..We conclude that in addition to the epsilon 4 allele, also the -219G/T promoter polymorphism of the apo E gene is associated with early onset CHD...
  6. ncbi Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes
    J Pihlajamaki
    University of Kuopio, Department of Medicine, Kuopio, Finland
    Diabetologia 49:1560-6. 2006
    ....
  7. ncbi Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study
    O Laukkanen
    Department of Medicine, University of Kuopio, Finland
    Diabetologia 47:871-7. 2004
    ....
  8. ncbi Codon 54 polymorphism of the human intestinal fatty acid binding protein 2 gene is associated with dyslipidemias but not with insulin resistance in patients with familial combined hyperlipidemia
    J Pihlajamaki
    Department of Medicine, University of Kuopio, Finland
    Arterioscler Thromb Vasc Biol 17:1039-44. 1997
    ..042), and high LDL triglycerides (P = .013) but not with insulin resistance in subjects from FCHL families. The FABP2 gene is unlikely to be a major gene for FCHL, but it might affect lipid metabolism in subjects with FCHL...
  9. ncbi Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men
    J Vangipurapu
    Department of Medicine, University of Eastern Finland, Kuopio University Hospital, 70210, Kuopio, Finland
    Diabetologia 54:563-71. 2011
    ..We examined the association of indices of hepatic and adipocyte insulin resistance (IR) with 19 confirmed type 2 diabetes risk loci in a large population-based study...
  10. ncbi Diverse associations of 25-hydroxyvitamin D and 1,25-dihydroxy-vitamin D with dyslipidaemias
    P Karhapaa
    Department of Medicine, University of Eastern Finland, Kuopio, Finland
    J Intern Med 268:604-10. 2010
    ..Therefore, we studied the associations between both 25-D and 1,25-D and total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides in a population-based study...
  11. ncbi Association of angiotensin converting enzyme and plasminogen activator inhibitor-1 promoter gene polymorphisms with features of the insulin resistance syndrome in patients with premature coronary heart disease
    L Viitanen
    Department of Medicine, University of Kuopio, PO Box 1627, 70 211 Kuopio, Finland
    Atherosclerosis 157:57-64. 2001
    ..In conclusion, the ACE and PAI-1 gene polymorphisms are not linked with early-onset CHD. However, the ACE gene polymorphism is associated with features of the insulin resistance syndrome...