Research Topics
| Pasi T PennanenSummaryAffiliation: University of Tampere Country: Finland Publications
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Detail Information
Publications
Changes in protein tyrosine phosphatase type IVA member 1 and zinc finger protein 36 C3H type-like 1 expression demonstrate altered estrogen and progestin effect in medroxyprogesterone acetate-resistant and estrogen-independent breast cancer cell modelsPasi T Pennanen
Department of Cell Biology, Medical School, FIN 33014 University of Tampere, Tampere, Finland
Steroids 74:404-9. 2009..This study suggests an important role for PTP4A1 in cell growth, and shows that MPA may potentiate the effect of 17beta-estradiol in the MPA-resistant breast cancer cells...
Gene expression changes during the development of estrogen-independent and antiestrogen-resistant growth in breast cancer cell culture modelsPasi T Pennanen
Department of Cell Biology, Medical School, University of Tampere, Tampere, Finland
Anticancer Drugs 20:51-8. 2009..Then, after prolonged treatment with antiestrogen, the antiestrogen-resistant cells may eventually generate an E2-agonistic response to antiestrogen, probably acquiring additional growth advantage...
Inhibition of FOSL1 overexpression in antiestrogen-resistant MCF-7 cells decreases cell growth and increases vacuolization and cell deathPasi T Pennanen
Department of Cell Biology, Medical School, FIN 33014, University of Tampere, Finland
Steroids 76:1063-8. 2011..The inhibition of FOSL1 expression in these cells also restored sensitivity to TOR. Our results suggest that chemotherapy targeting overexpression of FOSL1 could be a potent strategy for treating endocrine resistant breast cancers...
