Research Topics
Species | Csaba OrtutaySummaryAffiliation: University of Tampere Country: Finland Publications
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Detail Information
Publications
PseudoGeneQuest - service for identification of different pseudogene types in the human genomeCsaba Ortutay
Institute of Medical Technology, University of Tampere, FI 33014 Tampere, Finland
BMC Bioinformatics 9:299. 2008..PseudoGeneQuest is an online tool to search the human genome for a given query sequence and to identify different types of pseudogenes as well as novel genes and gene fragments...
Immunome knowledge base (IKB): an integrated service for immunome researchCsaba Ortutay
Institute of Medical Technology, FI 33014 University of Tampere, Finland
BMC Immunol 10:3. 2009..However, these data are scattered into several databases and literature and therefore integration is needed...
Molecular characterization of the immune system: emergence of proteins, processes, and domainsCsaba Ortutay
Institute of Medical Technology, University of Tampere, 33014, Tampere, Finland
Immunogenetics 59:333-48. 2007..Immunome genes were found to have three types of emergence in independent studies of their ontologies, domains, and functions...
Immunome: a reference set of genes and proteins for systems biology of the human immune systemCsaba Ortutay
Institute of Medical Technology, FI-33014 University of Tampere, Finland
Cell Immunol 244:87-9. 2006..The reference set and the categories are freely available in the immunome database at http://bioinf.uta.fi/Immunome/...
Immunity genes and their orthologs: a multi-species databaseKathryn Rannikko
Bioinformatics Research Group, Institute of Medical Technology, FI 33014, University of Tampere, Finland
Int Immunol 19:1361-70. 2007..All the immunity genes and their evidence of immune function, orthologs and ortholog groups have been combined into an open access database -- ImmunomeBase, which is publicly available from (http://bioinf.uta.fi/ImmunomeBase)...
Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficienciesCsaba Ortutay
Institute of Medical Technology, FI 33014 University of Tampere and Tampere University Hospital, FI 33520 Tampere, Finland
Nucleic Acids Res 37:622-8. 2009..The method can be generalized for any disease group with sufficient information...
Systematic classification of primary immunodeficiencies based on clinical, pathological, and laboratory parametersCrina Samarghitean
Institute of Medical Technology, University of Tampere, Tampere, Finland
J Immunol 183:7569-75. 2009..The method can be applied to any group of diseases...
Phylogeny of Tec family kinases identification of a premetazoan origin of Btk, Bmx, Itk, Tec, Txk, and the Btk regulator SH3BP5Csaba Ortutay
Institute of Medical Technology, FI 33014 University of Tampere, Finland
Adv Genet 64:51-80. 2008..It is conserved in choanoflagellates and interestingly exists also in nematodes, which do not express TFKs, suggesting a broader function in addition to Btk regulation. The related SH3BP5-like protein is not found in Nematodes...
Carbonic anhydrase related protein VIII and its role in neurodegeneration and cancerAshok Aspatwar
University of Tampere School of Medicine, B Building, University of Tampere, Tampere, Finland
Curr Pharm Des 16:3264-76. 2010..The present review article describes the previous data on CARP VIII, including its structure, role in neurodegeneration and cancer; and bioinformatic and expression analyses recently performed in our laboratory...
Divergent microsatellite evolution in the human and chimpanzee lineagesZoltán Gáspári
Institute of Chemistry, Eotvos Lorand University, Pazmany Peter setany 1 A, H 1117 Budapest, Hungary
FEBS Lett 581:2523-6. 2007..In this paper, we show that this is valid for most of the chimpanzee genome but not for a number of human chromosomes. Our results suggest accelerated evolution of microsatellites in the human genome relative to the chimpanzee lineage...
Speciation in Chlamydia: genomewide phylogenetic analyses identified a reliable set of acquired genesCsaba Ortutay
Department of Genetics, , , Budapest H-1117, Hungary
J Mol Evol 57:672-80. 2003..Our analysis may provide a deeper insight into how these medically important pathogens emerged and evolved from a common ancestor...
