Research Topics
| Tuija H NieminenSummaryAffiliation: University of Turku Country: Finland Publications
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Detail Information
Publications
Voriconazole drastically increases exposure to oral oxycodoneNora M Hagelberg
Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University Hospital, PO Box 52 Kiinamyllynkatu 4 8, FI 20521 Turku, Finland
Eur J Clin Pharmacol 65:263-71. 2009..We investigated the effect of voriconazole on the pharmacokinetics and pharmacodynamics of oxycodone...
Rifampin greatly reduces the plasma concentrations of intravenous and oral oxycodoneTuija H Nieminen
Department of Anesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University Hospital, Turku, Finland
Anesthesiology 110:1371-8. 2009..The authors studied the interaction of rifampin with oxycodone. Their hypothesis was that rifampin enhances the CYP3A-mediated metabolism of oxycodone and attenuates its pharmacologic effect...
St John's wort greatly reduces the concentrations of oral oxycodoneTuija H Nieminen
Department of Anesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University Hospital and University of Turku, Turku, Finland
Eur J Pain 14:854-9. 2010..Chronic pain is associated with depression. Self-treatment of depression with herbal over-the-counter medicine St John's wort makes pain patients prone to drug interactions...
Grapefruit juice enhances the exposure to oral oxycodoneTuija H Nieminen
Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University Hospital, University of Turku, Turku, Finland
Basic Clin Pharmacol Toxicol 107:782-8. 2010..We conclude that dietary consumption of grapefruit products may increase the concentrations and effects of oxycodone in clinical use...
Oxycodone concentrations are greatly increased by the concomitant use of ritonavir or lopinavir/ritonavirTuija H Nieminen
Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University Hospital and University of Turku, P O Box 52, Kiinamyllynkatu 4 8, 20521 Turku, Finland
Eur J Clin Pharmacol 66:977-85. 2010....
