Research Topics
| Yan Ru LouSummaryAffiliation: University of Helsinki Country: Finland Publications
|
Detail Information
Publications
25-Hydroxyvitamin D(3) is an agonistic vitamin D receptor ligandYan Ru Lou
Department of Anatomy, Medical School, University of Tampere, Tampere, FIN 33014, Finland
J Steroid Biochem Mol Biol 118:162-70. 2010..In conclusion, 25-hydroxyvitamin D(3) is an agonistic vitamin D receptor ligand with gene regulatory and anti-proliferative properties...- Inhibition of fatty acid synthase expression by 1alpha,25-dihydroxyvitamin D3 in prostate cancer cellsShengjun Qiao
Department of Anatomy, Medical School, 33014 University of Tampere, Tampere, Finland
J Steroid Biochem Mol Biol 85:1-8. 2003..The findings suggest that FAS is involved in the antiproliferative effect of 1alpha,25(OH)(2)D(3) in presence of androgens on prostate cancer LNCaP cells... - Role of 24-hydroxylase in vitamin D3 growth response of OVCAR-3 ovarian cancer cellsSusanna Miettinen
Department of Cell Biology, Medical School, University of Tampere, Tampere, Finland
Int J Cancer 108:367-73. 2004..The possible mitogenic effects of vitamin D should be considered when evaluating treatment of ovarian cancer with vitamin D... - Increased anxiety in mice lacking vitamin D receptor geneAllan V Kalueff
Department of Anatomy, Medical School, University of Tampere, FIN 33014 Tampere, Finland
Neuroreport 15:1271-4. 2004..These studies suggest that vitamin D and its receptors are an important factor in the brain, whose imbalance may significantly affect emotional behaviour... - Calcitriol-induced prostate-derived factor: autocrine control of prostate cancer cell growthNadja Nazarova
Department of Anatomy, Medical School, University of Tampere, Tampere, Finland
Int J Cancer 112:951-8. 2004..This is a new link between calcitriol and growth factors of TGF-beta superfamily in the control of prostate cell growth... - Vestibular dysfunction in vitamin D receptor mutant miceAnna Minasyan
Department of Anatomy, Medical School, University of Tampere, Finland
J Steroid Biochem Mol Biol 114:161-6. 2009..These data suggest that VDR deficiency in mice is associated with decreased balance function, and may be relevant to poorer balance/posture control in humans with low levels of vitamin D... - 25-hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cellsYan Ru Lou
Department of Anatomy, Medical School, FIN 33014, University of Tampere, Finland
FASEB J 18:332-4. 2004..Altogether our results suggest that 25OHD3 at a high but physiological concentration acts as an active hormone with respect to vitamin D3 responsive gene regulation and suppression of cell proliferation... - Impaired motor performance in mice lacking neurosteroid vitamin D receptorsAllan V Kalueff
Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland
Brain Res Bull 64:25-9. 2004..This study confirms the important role of the vitamin D system in motor functions and suggests that animal genetic models targeting the vitamin D/VDR system may be a useful tool to study vitamin D-related motor/behavioural disorders... - Thalamic calcification in vitamin D receptor knockout miceAllan Kalueff
Department of Anatomy, Medical School, University of Tampere, Finland
Neuroreport 17:717-21. 2006..Our results suggest that nuclear vitamin D receptor deficiency leads to brain mineralization in vitamin D receptor knockout mice, which may represent an experimental model of intracranial calcification... - Neophobia, sensory and cognitive functions, and hedonic responses in vitamin D receptor mutant miceAnna Minasyan
Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland
J Steroid Biochem Mol Biol 104:274-80. 2007.... - Androgen enhances the antiproliferative activity of vitamin D3 by suppressing 24-hydroxylase expression in LNCaP cellsYan Ru Lou
Department of Anatomy, Medical School, University of Tampere, and Department of Clinical Chemistry, Tampere University Hospital, FIN 33014, Finland
J Steroid Biochem Mol Biol 99:44-9. 2006..The combined use of androgen and Vitamin D3 metabolites could be a promising treatment for prostate cancer... - 5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cellsYan Ru Lou
Department of Anatomy, Medical School, University of Tampere, Finland
Prostate 63:222-30. 2005..A cross-talk between 1alpha,25-dihydroxyvitamin D(3) [1alpha,25-(OH)(2)D(3)] and 5alpha-dihydrotestosterone (DHT) in the growth inhibition has been demonstrated, but the mechanism is unknown... - Progressive hearing loss in mice with a mutated vitamin D receptor geneJing Zou
Department of Otolaryngology, School of Medicine, University of Tampere, Tampere, Finland
Audiol Neurootol 13:219-30. 2008..Hormonal forms of vitamin D regulate transcription by binding with the high-affinity vitamin D receptor (VDR)... - Regulation of aromatase and 5alpha-reductase by 25-hydroxyvitamin D(3), 1alpha,25-dihydroxyvitamin D(3), dexamethasone and progesterone in prostate cancer cellsYan Ru Lou
Department of Anatomy, Medical School, University of Tampere, FIN 33014 Tampere, Finland
J Steroid Biochem Mol Biol 94:151-7. 2005..The expression of 5alpha-reductase type I mRNA was not regulated by 1alpha,25-(OH)(2)D(3) and no expression of 5alpha-reductase type II was detected in LNCaP... - Premature aging in vitamin D receptor mutant miceTiina Keisala
Department of Anatomy, Medical School, University of Tampere, Tampere 33014, Finland
J Steroid Biochem Mol Biol 115:91-7. 2009.... - Abnormal behavioral organization of grooming in mice lacking the vitamin D receptor geneAllan V Kalueff
Department of Anatomy, Medical School, University of Tampere, Tampere, Finland
J Neurogenet 19:1-24. 2005..Our results suggest that a neurosteroid vitamin D and VDR may play an important role in controlling sequencing of grooming in mice, and further confirm the important role of the vitamin D system and VDR in the regulation of behavior...