Kai Lehtimäki

Summary

Affiliation: Tampere University Hospital
Country: Finland

Publications

  1. ncbi Increase in plasma proinflammatory cytokines after electroconvulsive therapy in patients with depressive disorder
    Kai Lehtimäki
    Department of Neurosurgery, Tampere University Hospital, University of Tampere, Tampere, Finland
    J ECT 24:88-91. 2008
  2. ncbi Levels of IL-1beta and IL-1ra in cerebrospinal fluid of human patients after single and prolonged seizures
    Kai A Lehtimaki
    Department of Neurosurgery, Tampere University Hospital, FI 33521 Tampere, Finland
    Neuroimmunomodulation 17:19-22. 2010
  3. ncbi Cardiolipin and ??-Glycoprotein I antibodies associate with cognitive impairment and seizure frequency in developmental disorders
    K A Lehtimäki
    Department of Neurosurgery, Tampere University Hospital, Teiskontie 35, 33521 Tampere, Finland
    Seizure 20:438-41. 2011
  4. ncbi The serum level of interleukin-6 in patients with intellectual disability and refractory epilepsy
    Kai A Lehtimaki
    Department of Neurosurgery, Tampere University Hospital, Teiskontie 35, Tampere, Finland
    Epilepsy Res 95:184-7. 2011
  5. ncbi Cranioplasty with adipose-derived stem cells and biomaterial: a novel method for cranial reconstruction
    Tuomo Thesleff
    Department of Neurosurgery, Tampere University Hospital, PO Box 2000, 33521 Tampere, Finland
    Neurosurgery 68:1535-40. 2011
  6. ncbi Intranasal administration of human IL-6 increases the severity of chemically induced seizures in rats
    Allan V Kalueff
    Medical School, University of Tampere, 33014, Finland
    Neurosci Lett 365:106-10. 2004

Collaborators

Detail Information

Publications6

  1. ncbi Increase in plasma proinflammatory cytokines after electroconvulsive therapy in patients with depressive disorder
    Kai Lehtimäki
    Department of Neurosurgery, Tampere University Hospital, University of Tampere, Tampere, Finland
    J ECT 24:88-91. 2008
    ..We have previously reported that epileptic seizures result in cerebral production of cytokines, which are also reflected in the plasma. In this study, we tested whether ECT is associated with similar acute release of cytokines...
  2. ncbi Levels of IL-1beta and IL-1ra in cerebrospinal fluid of human patients after single and prolonged seizures
    Kai A Lehtimaki
    Department of Neurosurgery, Tampere University Hospital, FI 33521 Tampere, Finland
    Neuroimmunomodulation 17:19-22. 2010
    ..In the present study, we determined the levels of proconvulsive IL-1beta and anticonvulsive IL-1ra in cerebrospinal fluid after single tonic-clonic seizures as well as after prolonged seizures...
  3. ncbi Cardiolipin and ??-Glycoprotein I antibodies associate with cognitive impairment and seizure frequency in developmental disorders
    K A Lehtimäki
    Department of Neurosurgery, Tampere University Hospital, Teiskontie 35, 33521 Tampere, Finland
    Seizure 20:438-41. 2011
    ..Present data demonstrates that epilepsy with frequently recurring seizures may be associated with secondary immune system activation...
  4. ncbi The serum level of interleukin-6 in patients with intellectual disability and refractory epilepsy
    Kai A Lehtimaki
    Department of Neurosurgery, Tampere University Hospital, Teiskontie 35, Tampere, Finland
    Epilepsy Res 95:184-7. 2011
    ..The patients showed significantly higher IL-6 levels than the controls (4.1±4.5pg/ml vs. 2.1±1.0pg/ml; p<0.001). High seizure frequency and severe intellectual disability emerged as predictors for elevated serum levels of IL-6...
  5. ncbi Cranioplasty with adipose-derived stem cells and biomaterial: a novel method for cranial reconstruction
    Tuomo Thesleff
    Department of Neurosurgery, Tampere University Hospital, PO Box 2000, 33521 Tampere, Finland
    Neurosurgery 68:1535-40. 2011
    ..There is no optimal method for reconstruction of large calvarial defects. Because of the limitations of autologous bone grafts and alloplastic materials, new methods for performing cranioplasties are needed...
  6. ncbi Intranasal administration of human IL-6 increases the severity of chemically induced seizures in rats
    Allan V Kalueff
    Medical School, University of Tampere, 33014, Finland
    Neurosci Lett 365:106-10. 2004
    ..Our findings show that IL-6 plays a pro-convulsant role in the brain and suggest that the IL-6 system may be a novel target for the development of anticonvulsant drugs...