Research Topics
| Virpi AholaSummaryAffiliation: MTT Agrifood Research Finland Country: Finland Publications
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Detail Information
Publications
Model-based prediction of sequence alignment qualityVirpi Ahola
Biotechnology and Food Research, MTT Agrifood Research Finland, FI 31600 Jokioinen, Finland
Bioinformatics 24:2165-71. 2008..Since the success of the sequence analysis is highly dependent on the reliability of alignments, measures for assessing the quality of alignments are highly requisite...
A statistical score for assessing the quality of multiple sequence alignmentsVirpi Ahola
Biotechnology and Food Research, MTT Agrifood Research Finland, Jokioinen, Finland
BMC Bioinformatics 7:484. 2006..Although the automatic construction of a multiple sequence alignment for a set of remotely related sequences cause a very challenging and error-prone task, many downstream analyses still rely heavily on the accuracy of the alignments...
An intronic insertion in KPL2 results in aberrant splicing and causes the immotile short-tail sperm defect in the pigAnu Sironen
MTT Agrifood Research Finland, Animal Production Research, Animal Breeding, FIN 31600, Jokioinen, Finland
Proc Natl Acad Sci U S A 103:5006-11. 2006..These findings show that the KPL2 gene is important for correct axoneme development and provide insight into abnormal sperm development and infertility disorders...
Efficient estimation of emission probabilities in profile hidden Markov modelsVirpi Ahola
Department of Statistics, FIN 20014 University of Turku, Finland
Bioinformatics 19:2359-68. 2003..For this reason, the number of estimated emission parameters is often enormous. Focusing the analysis on conserved residues only should increase the accuracy of sequence database search...
