Research Topics
| Riikka TulamoSummaryAffiliation: Helsinki University Central Hospital Country: Finland Publications
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Detail Information
Publications
Lack of complement inhibitors in the outer intracranial artery aneurysm wall associates with complement terminal pathway activationRiikka Tulamo
Neurosurgery Research Group, Room B408a2, Biomedicum Helsinki 1, P O Box 700, FI 00029 Huch, Finland
Am J Pathol 177:3224-32. 2010..Apparently, disturbed complement regulation leads to an increased susceptibility to complement activation, inflammation, and tissue damage in the IA wall...
Complement activation associates with saccular cerebral artery aneurysm wall degeneration and ruptureRiikka Tulamo
Neurosurgery Research Group, Room B408a2, Biomedicum Helsinki, P O Box 700, FI 00029 Huch, Finland
Neurosurgery 59:1069-76; discussion 1076-7. 2006..We studied how complement activation associates with SCAA wall degeneration and rupture to better understand the pathobiology of SCAA wall rupture...
Complement system becomes activated by the classical pathway in intracranial aneurysm wallsRiikka Tulamo
Neurosurgery Research Group, Biomedicum Helsinki, Helsinki, Huch FI 00029, Finland
Lab Invest 90:168-79. 2010..The observed pattern of complement activation may be the consequence of local stress-induced insufficiency of complement regulation in IA walls...
Inflammatory changes in the aneurysm wall: a reviewRiikka Tulamo
Neurosurgery Research Group, Biomedicum Helsinki, Finland
J Neurointerv Surg 2:120-30. 2010..We also discuss current options in imaging inflammation and how knowledge of inflammation in IA walls may improve IA treatment...
Occlusion of neck remnant in experimental rat aneurysms after treatment with platinum- or polyglycolic-polylactic acid-coated coilsJohan Marjamaa
Neurosurgery Research Group, Biomedicum Helsinki, Finland
Surg Neurol 71:458-65; discussion 465. 2009..We compared the evolution of neck remnants of experimental arterial rat aneurysms after treatment with either platinum- or PGLA-coated coils...
Isolation, culture, and characterization of smooth muscle cells from human intracranial aneurysmsHenrik Bygglin
Biomedicum Helsinki, Helsinki University Central Hospital, Finland
Acta Neurochir (Wien) 153:311-8. 2011..Our aim was to investigate the possibility of using cultured SMCs as an in vitro model for the study of aneurysmal SMCs...
Association of fatal aneurysmal subarachnoid hemorrhage with human leukocyte antigens in the Finnish populationJuhana Frösen
Neurosurgery Research Group, Biomedicum Helsinki, Helsinki, Finland
Hum Immunol 68:100-5. 2007..5 for HLA-DR7. HLA-A3 seems to associate with fatal SAH in the Finnish population. Further studies are needed to reveal the pathobiologic mechanisms for how HLA-A3 associates with the risk of fatal SAH in Finns...
Contribution of mural and bone marrow-derived neointimal cells to thrombus organization and wall remodeling in a microsurgical murine saccular aneurysm modelJuhana Frösen
Neurosurgery Research Group, Biomedicum Helsinki, and Transplantation Laboratory, University of Helsinki, Helsinki, Finland
Neurosurgery 58:936-44; discussion 936-44. 2006..Bone marrow-derived progenitor cells may contribute to these processes, but their role in human saccular cerebral artery aneurysms and experimental aneurysm models remains unclear...
Involvement of mitogen-activated protein kinase signaling in growth and rupture of human intracranial aneurysmsElisa Laaksamo
Biomedicum Helsinki, Helsinki University Central Hospital, Helsinki, Finland
Stroke 39:886-92. 2008..We investigated the expression and phosphorylation of the 3 major mitogen-activated protein kinases, c-Jun N-terminal kinase (JNK), p38, and extracellular signal-regulated kinase, in unruptured and ruptured human IAs...
