Marion Hückel

Summary

Affiliation: F. Hoffmann-La Roche Ltd

Publications

  1. ncbi Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1)
    Marion Hückel
    Institute of Pathology, Friedrich Schiller University, Jena, Germany
    Arthritis Res Ther 8:R17. 2006
  2. ncbi Interactions of T helper cells with fibroblast-like synoviocytes: up-regulation of matrix metalloproteinases by macrophage migration inhibitory factor from both Th1 and Th2 cells
    Uta Schurigt
    University Hospital Jena, Jena, Germany
    Arthritis Rheum 58:3030-40. 2008
  3. ncbi Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis
    Uta Schurigt
    Institute of Pathology, Friedrich Schiller University, Jena, Germany
    Arthritis Res Ther 7:R174-88. 2005

Detail Information

Publications3

  1. ncbi Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1)
    Marion Hückel
    Institute of Pathology, Friedrich Schiller University, Jena, Germany
    Arthritis Res Ther 8:R17. 2006
    ..The beneficial effects of the STAT-1 decoy ODN in experimental arthritis presumably mediated in part by affecting CD40 signalling in macrophages may provide the basis for a novel treatment of human RA...
  2. ncbi Interactions of T helper cells with fibroblast-like synoviocytes: up-regulation of matrix metalloproteinases by macrophage migration inhibitory factor from both Th1 and Th2 cells
    Uta Schurigt
    University Hospital Jena, Jena, Germany
    Arthritis Rheum 58:3030-40. 2008
    ....
  3. ncbi Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis
    Uta Schurigt
    Institute of Pathology, Friedrich Schiller University, Jena, Germany
    Arthritis Res Ther 7:R174-88. 2005
    ..TIMP-3 showed an expression profile similar to that of anti-inflammatory interleukin-4. The present study indicates that MMPs and cathepsins are important in AIA and contribute to the degradation of cartilage and bone...