Stephen P East

Summary

Affiliation: Evotec OAI

Publications

  1. ncbi Peptide deformylase inhibitors with activity against respiratory tract pathogens
    Stephen P East
    British Biotech Pharmaceuticals Limited, Watlington Road, Oxford OX4 6LY, UK
    Bioorg Med Chem Lett 14:59-62. 2004
  2. ncbi Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group
    Helen K Smith
    British Biotech Pharmaceuticals Limited, Watlington Road, Oxford OX4 6LY, UK
    Bioorg Med Chem Lett 12:3595-9. 2002

Collaborators

  • J M Clements
  • Helen K Smith
  • Wayne Thomas
  • R Paul Beckett
  • Lisa M Pratt
  • Steven B Launchbury
  • Mark Whittaker
  • Richard S Todd
  • Sheila Doel

Detail Information

Publications2

  1. ncbi Peptide deformylase inhibitors with activity against respiratory tract pathogens
    Stephen P East
    British Biotech Pharmaceuticals Limited, Watlington Road, Oxford OX4 6LY, UK
    Bioorg Med Chem Lett 14:59-62. 2004
    ..The in vitro antibacterial profiling of these compounds revealed that they demonstrate activity against pathogens associated with respiratory tract infections...
  2. ncbi Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the metal binding group
    Helen K Smith
    British Biotech Pharmaceuticals Limited, Watlington Road, Oxford OX4 6LY, UK
    Bioorg Med Chem Lett 12:3595-9. 2002
    ..Enzyme inhibition and antibacterial activity data for these compounds revealed that the bidentate hydroxamic acid and N-formyl hydroxylamine structural motifs represent the optimum chelating groups on the pseudopeptidic BB-3497 backbone...