Research Topics
| Tuuli MetsvahtSummaryAffiliation: University of Tartu Country: Estonia Publications
| Collaborators
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Detail Information
Publications
Meropenem vs standard of care for treatment of late onset sepsis in children of less than 90 days of age: study protocol for a randomised controlled trialIrja Lutsar
Institute of Microbiology, University of Tartu, Estonia
Trials 12:215. 2011..The study will start recruitment in September 2011; the total duration is of 24 months. TRIAL REGISTRATION: EudraCT 2011-001515-31...
Ampicillin versus penicillin in the empiric therapy of extremely low-birthweight neonates at risk of early onset sepsisTuuli Metsvaht
Pediatric Intensive Care, Tallinn Children s Hospital, Tallinn, Estonia
Pediatr Int 53:873-80. 2011..There are no comparative data on the impact of different empiric antibiotic regimens on early bowel colonization as well as on clinical efficacy in extremely low-birthweight (ELBW) neonates at risk of early onset sepsis (EOS)...
Comparison of ampicillin plus gentamicin vs. penicillin plus gentamicin in empiric treatment of neonates at risk of early onset sepsisT Metsvaht
Paediatric Intensive Care Unit, Clinic of Anaesthesiology and Intensive Care, Tartu University Clinics, Tartu, Estonia
Acta Paediatr 99:665-72. 2010..We aimed to compare the clinical efficacy of ampicillin (AMP) vs. penicillin (PEN) both combined with gentamicin in the empirical treatment of neonates at risk of early onset neonatal sepsis (EOS)...
Clinical parameters predicting failure of empirical antibacterial therapy in early onset neonatal sepsis, identified by classification and regression tree analysisTuuli Metsvaht
Paediatric Intensive Care Unit, Clinic of Anaesthesiology and Intensive Care, Tartu University Clinics, Lunini 6, 51014 Tartu, Estonia
BMC Pediatr 9:72. 2009..We aimed to identify clinical and laboratory markers associated with empiric antibiotic treatment failure in neonates with suspected EOS...
Aortic arch thrombosis in a neonate with heterozygous carrier status of factor V Leiden mutationTuuli Metsvaht
Clinic of Anesthesiology and Intensive Care, Tartu University Clinics, Tartu, Estonia
Congenit Heart Dis 1:40-5. 2006..In chronic organized thrombi thrombolytic therapy is likely to fail...
Pharmacokinetics of penicillin g in very-low-birth-weight neonatesTuuli Metsvaht
Neonatal Intensive Care Unit, Tartu University Clinics, Lunini 6, 51014 Tartu, Estonia
Antimicrob Agents Chemother 51:1995-2000. 2007..We conclude that in VLBW infants a PEN dose of 25,000 IU (15 mg)/kg q12h is safe and sufficient to achieve serum concentrations above the MIC(90) for group B streptococci for the entire dosing interval...
Blood loss related to participation in pharmacokinetic study in preterm neonatesLenne Triin Heidmets
Department of Pharmacology, University of Tartu, Tartu, Estonia
Neonatology 100:111-5. 2011..The amount of blood that can be safely drawn from a preterm neonate for scientific purposes is poorly established...
Inflicted traumatic brain injury (ITBI) or shaken baby syndrome (SBS) in EstoniaInga Talvik
Children s Clinic, Tartu University Hospital, Estonia
Acta Paediatr 95:799-804. 2006..Inflicted traumatic brain injury (ITBI) or shaken baby syndrome (SBS) is recognized as a major cause of disability and death in the paediatric population...
Low cerebral blood flow velocity and head circumference in infants with severe hypoxic ischemic encephalopathy and poor outcomePilvi Ilves
Radiology Service, Tartu University Hospital, Tartu, Estonia
Acta Paediatr 98:459-65. 2009..To evaluate long-term changes in cerebral blood flow velocity (CBFV) and head circumference in asphyxiated infants...
Acutely and retrospectively diagnosed perinatal stroke: a population-based studyRael Laugesaar
Children s Clinic of Tartu University Hospital, Tartu, Estonia
Stroke 38:2234-40. 2007....
Understanding pharmacokinetics/pharmacodynamics in managing neonatal sepsisIrja Lutsar
Tartu University, Institute of Medical Microbiology, Tartu, Estonia
Curr Opin Infect Dis 23:201-7. 2010..This review describes recent pharmacokinetic and/or pharmacodynamic studies of antimicrobial agents used for treatment of neonatal sepsis...
Drug utilisation pattern and off-label use of medicines in Estonian neonatal unitsJana Lass
Institute of Microbiology, Tartu University, Tartu, Estonia
Eur J Clin Pharmacol 67:1263-71. 2011..To characterise neonatal hospital drug use and to compare the availability of drug information between Estonian Summaries of Product Characteristics (SPCs) and other sources...
Descriptive epidemiology of spinal muscular atrophy type I in EstoniaEve Vaidla
Department of Paediatrics, Tartu University, Tartu, Estonia
Neuroepidemiology 27:164-8. 2006..Only one of the patients was female. Typical SMN1 gene deletion was found in all cases...
