'Genome order index' should not be used for defining compositional constraints in nucleotide sequencesEran Elhaik
Department of Biology and Biochemistry, University of Houston, Houston, TX 77204 5001, USA
Comput Biol Chem 32:147. 2008
..Moreover, we show that S is strictly equivalent to and derivable from the Shannon H-function and has no advantage over it...
Comparative testing of DNA segmentation algorithms using benchmark simulationsEran Elhaik
Department of Biology and Biochemistry, University of Houston, TX, USA
Mol Biol Evol 27:1015-24. 2010
..However, even these algorithms perform poorly in certain instances because of the arbitrary choice of a segmentation-stopping criterion...
'Genome order index' should not be used for defining compositional constraints in nucleotide sequences--a case study of the Z-curveEran Elhaik
McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Biol Direct 5:10. 2010
..They claimed that an inscribed sphere of radius r = 1/ square root 3 contains almost all points corresponding to various genomes, implying that S <r2. The distribution of the points P obtained by S was studied using the Z-curve...
Identifying compositionally homogeneous and nonhomogeneous domains within the human genome using a novel segmentation algorithmEran Elhaik
McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Nucleic Acids Res 38:e158. 2010
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Can GC content at third-codon positions be used as a proxy for isochore composition?Eran Elhaik
Department of Biology and Biochemistry, University of Houston, TX, USA
Mol Biol Evol 26:1829-33. 2009
..We conclude that the GC content of third-codon position cannot be used as stand-in for isochoric composition...
The genome of the model beetle and pest Tribolium castaneumStephen Richards
Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
Nature 452:949-55. 2008
..Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control...
The genome of the sea urchin Strongylocentrotus purpuratusErica Sodergren
Science 314:941-52. 2006
..This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes...