Tarek H el-Metwally

Summary

Publications

  1. ncbi Natural retinoids inhibit proliferation and induce apoptosis in pancreatic cancer cells previously reported to be retinoid resistant
    Tarek H el-Metwally
    Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, Nebraska, USA
    Cancer Biol Ther 4:474-83. 2005
  2. ncbi High concentrations of retinoids induce differentiation and late apoptosis in pancreatic cancer cells in vitro
    Tarek H el-Metwally
    Department of Biomedical Sciences, Creighton University School of Medicine, Eppley Cancer Institute, University of Nebraska Medical Center, Omaha, NE, USA
    Cancer Biol Ther 4:602-11. 2005
  3. ncbi Retinoic acid can induce markers of endocrine transdifferentiation in pancreatic ductal adenocarcinoma: preliminary observations from an in vitro cell line model
    T H El-Metwally
    Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt
    J Clin Pathol 59:603-10. 2006
  4. ncbi The retinoid induced pancreatic cancer redifferentiation-apoptosis sequence and the mitochondria: a suggested obligatory sequence of events
    Tarek H el-Metwally
    Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt
    JOP 8:268-78. 2007
  5. ncbi The effectiveness of retinoic acid treatment in bladder cancer: impact on recurrence, survival and TGFalpha and VEGF as end-point biomarkers
    Diaa A Hameed
    Department of Urology, Faculty of Medicine, Assiut University, Assiut, Egypt
    Cancer Biol Ther 7:92-100. 2008

Detail Information

Publications5

  1. ncbi Natural retinoids inhibit proliferation and induce apoptosis in pancreatic cancer cells previously reported to be retinoid resistant
    Tarek H el-Metwally
    Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, Nebraska, USA
    Cancer Biol Ther 4:474-83. 2005
    ..This investigation tested the hypothesis that all-trans retinoic acid can inhibit proliferation and induce apoptosis in pancreatic cancer cell lines...
  2. ncbi High concentrations of retinoids induce differentiation and late apoptosis in pancreatic cancer cells in vitro
    Tarek H el-Metwally
    Department of Biomedical Sciences, Creighton University School of Medicine, Eppley Cancer Institute, University of Nebraska Medical Center, Omaha, NE, USA
    Cancer Biol Ther 4:602-11. 2005
    ..In this investigation, we hypothesize that high concentrations of retinoids can induce phenotypic changes (differentiation) and late apoptosis in pancreatic cancer cells in vitro...
  3. ncbi Retinoic acid can induce markers of endocrine transdifferentiation in pancreatic ductal adenocarcinoma: preliminary observations from an in vitro cell line model
    T H El-Metwally
    Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt
    J Clin Pathol 59:603-10. 2006
    ..The pancreatic ductal adenocarcinoma (HPAF) cells have a multipotent stem cell potential. It was hypothesised that all-trans-retinoic acid (atRA) can induce transdifferentiation of these cells into cells with an endocrine phenotype...
  4. ncbi The retinoid induced pancreatic cancer redifferentiation-apoptosis sequence and the mitochondria: a suggested obligatory sequence of events
    Tarek H el-Metwally
    Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt
    JOP 8:268-78. 2007
    ..Similarly, it is suggested that a degree of normalizing redifferentiation of transformed cells might be expected prior to apoptosis. The former seemed obligatory at least in the retinoid-pancreatic model...
  5. ncbi The effectiveness of retinoic acid treatment in bladder cancer: impact on recurrence, survival and TGFalpha and VEGF as end-point biomarkers
    Diaa A Hameed
    Department of Urology, Faculty of Medicine, Assiut University, Assiut, Egypt
    Cancer Biol Ther 7:92-100. 2008
    ..VEGF and TGFalpha levels are end-point pathogenetic biomarkers involved in early SBC...