Research Topics
| T H MogensenSummaryAffiliation: University of Copenhagen Country: Denmark Publications
| Collaborators
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Detail Information
Publications
Pathogen recognition and inflammatory signaling in innate immune defensesTrine H Mogensen
Department of Infectious Diseases, Aarhus University Hospital, Skejby, Aarhus, Denmark
Clin Microbiol Rev 22:240-73, Table of Contents. 2009....
Chronic hepatitis caused by persistent parvovirus B19 infectionTrine H Mogensen
Department of Infectious Diseases, Aarhus University Hospital, Skejby, DK 8200 Aarhus N, Denmark
BMC Infect Dis 10:246. 2010..This has prompted important questions regarding the tropism of the virus and its possible involvement in a broad range of infectious and autoimmune medical conditions...
Innate immune recognition and activation during HIV infectionTrine H Mogensen
Department of Infectious Diseases, Aarhus University Hospital, Skejby, DK 8200, Aarhus N, Denmark
Retrovirology 7:54. 2010....
Streptococcus pneumoniae stabilizes tumor necrosis factor alpha mRNA through a pathway dependent on p38 MAPK but independent of Toll-like receptorsTrine H Mogensen
Department of Infectious Diseases, Skejby Hospital Aarhus University Hospital, DK 8200, Aarhus N, Denmark
BMC Immunol 9:52. 2008..Infections with S. pneumoniae evoke a strong inflammatory response, which plays a major role in the pathogenesis of pneumococcal disease...
Mechanisms of dexamethasone-mediated inhibition of Toll-like receptor signaling induced by Neisseria meningitidis and Streptococcus pneumoniaeTrine H Mogensen
Department of Infectious Diseases, Skejby Hospital, Brendstrupgaardsvej, DK 8200 Aarhus N, Denmark
Infect Immun 76:189-97. 2008..meningitidis and S. pneumoniae, which may contribute to our understanding of the clinical effect and the importance of timing with respect to corticosteroid treatment during bacterial meningitis...
Acute demyelinizating encephalomyelitis (ADEM) as initial presentation of primary HIV infectionTrine H Mogensen
Department of Infectious Diseases, Skejby Hospital, University Hospital of Aarhus, Aarhus N, Denmark
Scand J Infect Dis 39:630-4. 2007..The aetiology, pathophysiology, diagnosis, and treatment of ADEM is reviewed, and the sparse existing literature on ADEM and HIV infection is discussed...
Two neisseria meningitidis strains with different ability to stimulate toll-like receptor 4 through the MyD88-independent pathwayT H Mogensen
Department of Infectious Diseases, Skejby Hospital, Aarhus, Denmark
Scand J Immunol 64:646-54. 2006..These data therefore provide molecular insight into activation of the inflammatory response by N. meningitidis, which is one of the key events in the pathogenesis of meningococcal disease...
Aseptic meningitis caused by reactivation of varicella-zoster virus in two immunocompetent patientsTrine H Mogensen
Department of Infectious Diseases, Skejby Hospital, University Hospital of Aarhus, Aarhus, Denmark
Scand J Infect Dis 38:815-8. 2006....
Live Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis activate the inflammatory response through Toll-like receptors 2, 4, and 9 in species-specific patternsTrine H Mogensen
Department of Infectious Diseases, Skejby Hospital, Brendstrupgaardsvej, DK 8200 Aarhus N, Denmark
J Leukoc Biol 80:267-77. 2006..pneumoniae, H. influenzae, and N. meningitidis each activate several TLRs in species-specific patterns and show that infection with live pathogens may lead to activation of PRR not targeted by inactivated bacteria...
Important role for Toll-like receptor 9 in host defense against meningococcal sepsisHong Sjölinder
Department of Medical Biochemistry and Microbiology, Biomedical Center, Uppsala University, P O Box 582, Uppsala, Sweden
Infect Immun 76:5421-8. 2008..In contrast, plasmacytoid dendritic cells relied entirely on TLR9 to induce these activities. Thus, our data demonstrate an important role for TLR9 in host defense against N. meningitidis...
p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infectionLeesun Kim
Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
J Immunol 174:4178-84. 2005..Furthermore, a synthetic p38 catalytic-site inhibitor blocked tachyzoite-induced p38alpha MAPK phosphorylation. These data are the first to demonstrate p38 MAPK autophosphorylation triggered by intracellular infection...
Long-term renal effects of a neutralizing RAGE antibody in obese type 2 diabetic miceAllan Flyvbjerg
Medical Department M and Medical Research Laboratories, Institute of Experimental Clinical Research, Aarhus University Hospital, Aarhus, Denmark
Diabetes 53:166-72. 2004..In conclusion, RAGE is an important pathogenetic factor in the renal changes in an animal model of type 2 diabetes...
Activation of NF-kappa B in virus-infected macrophages is dependent on mitochondrial oxidative stress and intracellular calcium: downstream involvement of the kinases TGF-beta-activated kinase 1, mitogen-activated kinase/extracellular signal-regulated kinTrine H Mogensen
Department of Medical Microbiology and Immunology, University of Aarhus, Aarhus, Denmark
J Immunol 170:6224-33. 2003....
[Toll-like receptors, a new way of treatment?]Claus Vinter Bødker Pedersen
Arhus Universitetshospital, Infektionsmedicinsk Afdeling Q, Skejby, Arhus N
Ugeskr Laeger 169:2193-8. 2007....
Suppression of proinflammatory cytokine expression by herpes simplex virus type 1Trine H Mogensen
Department of Medical Microbiology and Immunology, The Bartholin Building, University of Aarhus, DK-8000 Aarhus C, Denmark
J Virol 78:5883-90. 2004..Thus, HSV is able to suppress expression of proinflammatory cytokines by decreasing the stability of mRNAs, thereby potentially impeding the antiviral host response to infection...
