Research Topics
Genomes and GenesSpecies | Jacob v B HjelmborgSummaryAffiliation: University of Southern Denmark Country: Denmark Publications
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Detail Information
Publications
Determining the waist circumference in african americans which best predicts insulin resistanceAnne E Sumner
Clinical Endocrinology Branch, NIDDK, Bethesda, Maryland, USA
Obesity (Silver Spring) 16:841-6. 2008..In African Americans, insulin resistance (in men) was best predicted by a WC > or =102 cm, and in women by a WC > or =98 cm, or by a BMI value that fell in the obese category (men: > or =30 kg/m(2), women: > or =32 kg/m(2))...
Genetic influence on human lifespan and longevityJacob vB Hjelmborg
Institute of Public Health, University of Southern Denmark, J B Winslovsvej 9 B, 5000, Odense C, Denmark
Hum Genet 119:312-21. 2006..These findings provide a support for the search for genes affecting longevity in humans, especially at advanced ages...
Genetic influences on growth traits of BMI: a longitudinal study of adult twinsJacob v B Hjelmborg
Statistics and Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Obesity (Silver Spring) 16:847-52. 2008..To investigate the interplay between genetic factors influencing baseline level and changes in BMI in adulthood...
Longevity studies in GenomEUtwinAxel Skytthe
The Danish Twin Registry, Epidemiology Unit, Institute of Public Health, University of Southern Denmark, Odense, Denmark
Twin Res 6:448-54. 2003..Finally, it will provide a resource for identifying unusual sibships (i.e., dizygotic twin pairs) where both survived to extreme ages, as a basis for discovering genetic variants of importance for extreme survival...
Leukocyte telomere length is inversely correlated with plasma Von Willebrand factorJacob v B Hjelmborg
The Danish Aging Research Center and Research unit of Biostatistics, Institute of Public Health, University of Southern Denmark
Thromb Res 125:e339-42. 2010..Such a process would heighten the rate of age-dependent LTL attrition, ultimately resulting in shortened LTL...
Perceived age as clinically useful biomarker of ageing: cohort studyKaare Christensen
Danish Twin Registry and Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, DK 5000 Odense C, Denmark
BMJ 339:b5262. 2009..To determine whether perceived age correlates with survival and important age related phenotypes...
Genetic and environmental influences of surfactant protein D serum levelsGrith L Sørensen
Medical Biotechnology Center, Institute for Medical Biology, University of Southern Denmark, Winsloewparken 25 3, DK 5000 Odense, Denmark
Am J Physiol Lung Cell Mol Physiol 290:L1010-7. 2006..19), additive genetic effects (h(2) = 0.42), and the effect of the Met11Thr variations (q(2) = 0.39)...
Cancer and Longevity--Is There a Trade-off? A Study of Cooccurrence in Danish Twin Pairs Born 1900-1918Kaare Christensen
DThe Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, J B Winsløws Vej 9B, DK 5000 Odense C, Denmark
J Gerontol A Biol Sci Med Sci 67:489-94. 2012..This hypothesis predicts that longevity in one twin is associated with increased cancer risk in the cotwin...
Leukocyte telomere length and physical ability among Danish twins age 70+Laila Bendix
Danish Aging Research Center, University of Southern Denmark, JB Winslowsvej 9B, DK 5000 Odense C, Denmark
Mech Ageing Dev 132:568-72. 2011..The LTL-physical ability association in the elderly provides further support to the premise that LTL is an index of somatic fitness in the narrow context of human physical health...
Importance of genetic factors in the etiology of atopic dermatitis: a twin studySimon F Thomsen
Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark
Allergy Asthma Proc 28:535-9. 2007..98). The estimates were adjusted for age. The susceptibility to develop atopic dermatitis is attributable to mainly genetic differences between people. However, differences in environmental exposures also are of importance...
The 5-HT2A receptor binding pattern in the human brain is strongly genetically determinedLars H Pinborg
Neurobiology Research Unit and Center for Integrated Molecular Brain Imaging, Copenhagen University Hospital, Rigshospitalet, N9201, 9 Blegdamsvej, DK 2100 Copenhagen, Denmark
Neuroimage 40:1175-80. 2008....
Telomere length and mortality: a study of leukocytes in elderly Danish twinsMasayuki Kimura
Center of Human Development and Aging, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
Am J Epidemiol 167:799-806. 2008..Leukocyte telomere dynamics might help explain the boundaries of the human life span...
The tumor necrosis factor alpha -308G>A polymorphism is associated with dementia in the oldest oldHelle Bruunsgaard
Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
J Am Geriatr Soc 52:1361-6. 2004..To test the hypothesis that the tumor necrosis factor (TNF) -308 G>A promoter gene polymorphism is a risk factor in age-related dementia and longevity...
Heritability of adult body height: a comparative study of twin cohorts in eight countriesKarri Silventoinen
Department of Public Health, University of Helsinki, Finland
Twin Res 6:399-408. 2003..Our results indicate that, in general, there are only minor differences in the genetic architecture of height between affluent Caucasian populations, especially among men...
