Research Topics
Species | C ErikstrupSummaryAffiliation: University of Copenhagen Country: Denmark Publications
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Detail Information
Publications
Downregulation of MIP-1alpha/CCL3 with praziquantel treatment in Schistosoma haematobium and HIV-1 co-infected individuals in a rural community in ZimbabweRbl Zinyama-Gutsire
Biochemistry Department, University of Zimbabwe, Harare, Zimbabwe
BMC Infect Dis 9:174. 2009..However there is less information on their role in Schistosoma haematobium infection, or on the effect of concurrent HIV-1 infection, as a potential modifying influence...
p24 as a predictor of mortality in a cohort of HIV-1-infected adults in rural AfricaChristian Erikstrup
The Centre of Inflammation and Metabolism, Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
J Acquir Immune Defic Syndr 48:345-9. 2008..p24 measurements have been proposed as an alternative to HIV-RNA because of the low cost of reagents and equipment needed. Here, we evaluate p24 as a prognostic marker in a cohort of HIV-1-infected individuals in Zimbabwe...
Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adultsChristian Erikstrup
Centre for Inflammation and Metabolism, Denmark
AIDS 21:2283-91. 2007..To evaluate the effect on HIV progression of single nucleotide polymorphisms in promoters of the genes for tumour necrosis factor (TNF)-alpha and interleukin (IL)-10 and known to influence cytokine production...
Predictors of mortality in a cohort of HIV-1-infected adults in rural AfricaChristian Erikstrup
Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Denmark
J Acquir Immune Defic Syndr 44:478-83. 2007..We explored the prognostic strengths of classic and alternative progression markers in this study set in rural Zimbabwe...
Short-term simvastatin treatment has no effect on plasma cytokine response in a human in vivo model of low-grade inflammationC Erikstrup
Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
Clin Exp Immunol 144:94-100. 2006..Tolerance to endotoxin was observed in both groups after 14 days. Short-term treatment with simvastatin (20 mg/day) did not influence circulating cytokine levels during endotoxaemia in this human in vivo study...
Associations between insulin resistance and TNF-alpha in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetesP Plomgaard
Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
Diabetologia 50:2562-71. 2007..Clear evidence exists that TNF-alpha inhibits insulin signalling and thereby glucose uptake in myocytes and adipocytes. However, conflicting results exist with regard to the role of TNF-alpha in type 2 diabetes...
RBP-to-retinol ratio, but not total RBP, is elevated in patients with type 2 diabetesC Erikstrup
Centre of Inflammation and Metabolism, Rigshospitalet and Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
Diabetes Obes Metab 11:204-12. 2009..We hypothesized that an imbalance between RBP and retinol might be the underlying cause for this association...
Brain-derived neurotrophic factor (BDNF) and type 2 diabetesK S Krabbe
The Centre of Inflammation and Metabolism, Department of Infectious Diseases, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
Diabetologia 50:431-8. 2007..These disorders are associated with type 2 diabetes, and animal models suggest that BDNF plays a role in insulin resistance. We therefore explored whether BDNF plays a role in human glucose metabolism...
Schistosomiasis and HIV in rural Zimbabwe: efficacy of treatment of schistosomiasis in individuals with HIV coinfectionPer Kallestrup
Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Clin Infect Dis 42:1781-9. 2006..Consequently, human immunodeficiency virus (HIV)-related immunodeficiency may impair the effect of praziquantel treatment...
Schistosomiasis and HIV-1 infection in rural Zimbabwe: effect of treatment of schistosomiasis on CD4 cell count and plasma HIV-1 RNA loadPer Kallestrup
Center for Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
J Infect Dis 192:1956-61. 2005..17). The present study suggests that treatment of schistosomiasis can reduce the rate of viral replication and increase CD4 cell count in the coinfected host...
Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasisChristian Erikstrup
Department of Clinical Immunology, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark
Am J Trop Med Hyg 79:331-7. 2008..Treatment for schistosomiasis caused a decrease in levels of sTNF-rII (P < 0.05) and IL-10 (P < 0.001). Our results indicate that schistosomiasis treatment may attenuate HIV replication by decreasing systemic inflammation...
Schistosomiasis and HIV-1 infection in rural Zimbabwe: implications of coinfection for excretion of eggsPer Kallestrup
Center of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
J Infect Dis 191:1311-20. 2005..This study explores the effect that HIV-1-associated immunodeficiency has on the excretion of schistosome eggs in a large cohort of coinfected individuals...
Retinol-binding protein 4 and insulin resistanceChristian Erikstrup
N Engl J Med 355:1393-4; author reply 1394-5. 2006
