Research Topics
| T L BenfieldSummaryAffiliation: University of Copenhagen Country: Denmark Publications
|
Detail Information
Publications
Pneumocystis carinii major surface glycoprotein induces interleukin-8 and monocyte chemoattractant protein-1 release from a human alveolar epithelial cell lineT L Benfield
University of Copenhagen, Hvidovre Hospital, Hvidovre, Denmark
Eur J Clin Invest 29:717-22. 1999..The major surface glycoprotein (MSG) is an abundant, immunogenic glycoprotein located on the surface of Pneumocystis carinii. Little is known about the proinflammatory effects of MSG...- Prognostic markers of short-term mortality in AIDS-associated Pneumocystis carinii pneumoniaT L Benfield
Department of Infectious Diseases, University of Copenhagen, Hvidovre Hospital, Hvidovre, Denmark
Chest 119:844-51. 2001..We hypothesized that the natural course of AIDS-associated PCP has changed in the era of adjunctive corticosteroid therapy... - Effects of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of AIDS-associated P. carinii pneumoniaJ Helweg-Larsen
Department of Infectious Diseases, University of Copenhagen, Hvidovre Hospital, Denmark
Lancet 354:1347-51. 1999..We assessed whether mutations in the DHPS gene of P. carinii were associated with exposure to sulpha drugs and influenced outcome from PCP... - Chemokine receptor CCR2b 64I polymorphism and its relation to CD4 T-cell counts and disease progression in a Danish cohort of HIV-infected individuals. Copenhagen AIDS cohortJ Eugen-Olsen
Department of Infectious Diseases, Copenhagen University Hospitals, Hvidovre, Denmark
J Acquir Immune Defic Syndr Hum Retrovirol 18:110-6. 1998..Furthermore, we were not able to detect any significant independent effect of the 64I allele on development to AIDS, overall survival, and annual CD4 T-cell decline in this cohort... - The major surface glycoprotein of Pneumocystis carinii induces release and gene expression of interleukin-8 and tumor necrosis factor alpha in monocytesT L Benfield
Department of Infectious Diseases, University of Copenhagen, Hvidovre Hospital, Denmark
Infect Immun 65:4790-4. 1997..These data show that recognition of MSG by monocytes involves a mannose-mediated mechanism and results in the release of the proinflammatory cytokines IL-8 and TNF-alpha... - Clinical correlation of variations in the internal transcribed spacer regions of rRNA genes in Pneumocystis carinii f.sp. hominisJ Helweg-Larsen
Department of Infectious Diseases, Hvidovre Hospital, 2650 Hvidovre, Denmark
AIDS 15:451-9. 2001..To analyse the importance of sequence variations in the internal transcribed spacer (ITS) regions 1 and 2 of the nuclear rRNA operon in AIDS patients with Pneumocystis carinii pneumonia (PCP)... - Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophiliaD Bang
Department of Infections Diseases, University of Copenhagen, Hvidovre Hospital, Hvidovre, Denmark
Respir Med 95:661-5. 2001..In conclusion, short-term mortality remained high after the introduction of adjunctive corticosteroid therapy. BAL neutrophilia may be a useful prognostic marker to identify patients at high risk of requiring mechanical ventilation... - Regional differences in use of antiretroviral agents and primary prophylaxis in 3122 European HIV-infected patients. EuroSIDA Study GroupJ D Lundgren
University of Copenhagen, Hvidovre Hospital, Denmark
J Acquir Immune Defic Syndr Hum Retrovirol 16:153-60. 1997..U.S. recommendations on the use of antimycobacterial prophylaxis have not been implemented in Europe... - Penicillin as empirical therapy for patients hospitalised with community acquired pneumonia at a Danish hospitalO Kirk
Department of Infectious Diseases, Department of Clinical Microbiology, and Clinic of Respiratory Medicine, H S Hvidovre Hospital, University of Copenhagen
Dan Med Bull 48:84-8. 2001..We report on the outcome of a study of patients hospitalised with community acquired pneumonia (HCAP) at a Danish university hospital...