Research Topics
Genomes and GenesSpecies | Mads Vilhelm HollegaardSummaryAffiliation: Statens Serum Institut Country: Denmark Publications
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Detail Information
Publications
Cytokine gene polymorphism in human disease: on-line databases, Supplement 3M V Hollegaard
NANEA at Department of Epidemiology, Institute of Public Health, University of Aarhus, Denmark
Genes Immun 7:269-76. 2006..nanea.dk/cytokinesnps/. The web pages also contain other features and downloads that could be useful when planning cytokine SNP association studies...
Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysisBo G Winkel
Dept of Cardiology, Rigshospitalet and Danish National Research Foundation Centre for Cardiac Arrhythmia DARC, Copenhagen, Denmark
BMC Med Genet 12:22. 2011..We wanted to compare melting curves and sequencing results from wgaDNA derived from DBS samples with gDNA derived from whole blood...
Polymorphisms in the tumor necrosis factor alpha and interleukin 1-beta promoters with possible gene regulatory functions increase the risk of preterm birthMads Vilhelm Hollegaard
Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Copenhagen, Denmark
Acta Obstet Gynecol Scand 87:1285-90. 2008..To investigate the relation between 19 selected single nucleotide polymorphisms in three cytokine genes, tumor necrosis factor alpha (TNFA), interleukin 1-beta (IL1B) and interleukin 6 (IL6) and preterm birth (<37 weeks' gestation)...
High-throughput genotyping on archived dried blood spot samplesMads V Hollegaard
Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Copenhagen, Denmark
Genet Test Mol Biomarkers 13:173-9. 2009..For evaluation of the biobank samples, we included variable factors: time of storage, gDNA, and whole-genome amplified DNA (wgaDNA) concentrations and the Illumina quality metric (GenCall score)...
Genome-wide scans using archived neonatal dried blood spot samplesMads V Hollegaard
Section of Neonatal Screening and Hormones, Statens Serum Institut, Copenhagen, Denmark
BMC Genomics 10:297. 2009..Whole-genome amplified DNA from 24 neonatal dried blood spot samples stored between 15 to 25 years was tested, and high-quality genomic DNA from 8 of the same individuals was used as reference...
Genotyping whole-genome-amplified DNA from 3- to 25-year-old neonatal dried blood spot samples with reference to fresh genomic DNAMads Vilhelm Hollegaard
Section of Neonatal Screening and Hormones, Statens Serum Institute, Copenhagen, Denmark
Electrophoresis 30:2532-5. 2009..Based on these results we conclude that DBS samples should be considered a reliable and potential resource for future genotyping studies...
Robustness of genome-wide scanning using archived dried blood spot samples as a DNA sourceMads V Hollegaard
Department of Clinical Biochemistry and Immunology, Statens Serum Institut, Ørestads Boulevard, Copenhagen, DK 2300, Denmark
BMC Genet 12:58. 2011..We examined the robustness of using DBS samples for whole-genome amplification following genome-wide scanning, using arrays from Illumina and Affymetrix...
Polymorphisms in the promoter region of relaxin-2 and preterm birth: involvement of relaxin in the etiology of preterm birthIda Vogel
Institute for Public Health, University of Aarhus, 8000 Aarhus C, Denmark
In Vivo 23:1005-9. 2009..Our aim was to investigate if mothers carrying promoter single nucleotide polymorphisms (SNPs) in one of the three relaxin genes (RLN1, RLN2, RLN3) are predisposed for PTB...
