Research Topics
| Søren H SindrupSummaryAffiliation: Odense University Hospital Country: Denmark Publications
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Detail Information
Publications
Antidepressants in the treatment of neuropathic painSøren H Sindrup
Department of Neurology, Odense University Hospital, DK 5000 Odense, Denmark
Basic Clin Pharmacol Toxicol 96:399-409. 2005..However, without head-to-head comparisons between antidepressants and other analgesics, it is not possible to provide real evidence-based treatment algorithms for neuropathic pain...- The NK1-receptor antagonist TKA731 in painful diabetic neuropathy: a randomised, controlled trialSøren H Sindrup
Department of Neurology, Odense University Hospital, Denmark
Eur J Pain 10:567-71. 2006..4 mm vs. -11.6 mm, p = 0.664) nor for change in ratings of different pain symptoms (touch- or pressure-evoked pain, pain paroxysms, steady burning or deep aching pain) (p = 0.169-0.834)... - Health-related quality of life and its predictive role for analgesic effect in patients with painful polyneuropathyMarit Otto
Department of Neurology, Odense University Hospital, DK 5000 Odense C, Denmark
Eur J Pain 11:572-8. 2007..Results show an impaired HRQL in painful polyneuropathy and suggest that HRQL may predict response to analgesic treatment... - Valproic acid has no effect on pain in polyneuropathy: a randomized, controlled trialMarit Otto
Department of Neurology, Odense University Hospital, Denmark
Neurology 62:285-8. 2004..There was no significant difference between valproic acid and placebo in the rating of total pain (median, 5 in the valproic acid period vs 6 in the placebo period; p = 0.24) or in individual pain ratings... - The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: a randomized, placebo-controlled, cross-over trialJakob V Holbech
Department of Neurology, Odense University Hospital, Denmark
Eur J Pain 15:608-14. 2011..This could have an impact on signaling in the nociceptive system, and a pilot study indicated relief of neuropathic pain with levetiracetam... - Escitalopram in painful polyneuropathy: a randomized, placebo-controlled, cross-over trialMarit Otto
Department of Neurology, Odense University Hospital, University of Southern Denmark, Sdr Boulevard 29, Odense C, Denmark
Pain 139:275-83. 2008..Currently, the drug cannot be recommended as a standard treatment in neuropathic pain... - Chronic neuropathic pain: mechanisms, drug targets and measurementNanna B Finnerup
Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, DK 8000 Aarhus, Denmark
Fundam Clin Pharmacol 21:129-36. 2007..The present review summarizes mechanisms of neuropathic pain, targets of currently used drugs, and measures used in neuropathic pain trials... - An evidence-based algorithm for the treatment of neuropathic painNanna B Finnerup
Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
MedGenMed 9:36. 2007..The purpose of this article is to discuss an evidence-based algorithm that can be implemented by the primary care physician in his/her daily clinical practice for the treatment of patients with neuropathic pain conditions... - A candidate gene study of serotonergic pathway genes and pain relief during treatment with escitalopram in patients with neuropathic pain shows significant association to serotonin receptor2C (HTR2C)Charlotte Brasch-Andersen
Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark
Eur J Clin Pharmacol 67:1131-7. 2011..The aim of this study was to investigate the association between polymorphisms in genes involved in the serotonergic pathway and the effect of escitalopram on peripheral neuropathic pain... - Pharmacotherapy of trigeminal neuralgiaSøren H Sindrup
Department of Neurology, Odense and Aarhus University Hospitals, Denmark
Clin J Pain 18:22-7. 2002..Controlled trials testing the effect of some of these drugs, new drugs, and drug combinations are needed...