Research Topics
Species | T MenneSummaryCountry: Denmark Publications
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Publications
Enhanced sensitization and elicitation responses caused by mixtures of common fragrance allergensCharlotte Menné Bonefeld
Faculty of Health Sciences, Department of International Health, Immunology and Microbiology, University of Copenhagen, DK 2200 Copenhagen, Denmark
Contact Dermatitis 65:336-42. 2011..It is therefore surprising that fragrance contact allergy is one of the most common forms of contact allergy...
Consumer available permanent hair dye products cause major allergic immune activation in an animal modelC M Bonefeld
Section of Experimental Immunology, Department of International Health, Immunology and Microbiology, Faculty of Health Sciences, University of Copenhagen, DK 2200 Copenhagen, Denmark
Br J Dermatol 162:102-7. 2010..Mixing the colour gel and developer (oxidant) increased the induction of skin inflammation compared with application of the colour gel alone...
Filaggrin loss-of-function mutation R501X and 2282del4 carrier status is associated with fissured skin on the hands: results from a cross-sectional population studyJ P Thyssen
National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
Br J Dermatol 166:46-53. 2012....
Inverse relationship between contact allergy and psoriasis: results from a patient- and a population-based studyN Bangsgaard
National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, DK 2900 Hellerup, Denmark
Br J Dermatol 161:1119-23. 2009..Psoriasis is an autoimmune disease and it has been debated whether contact allergy is less prevalent among patients with psoriasis. Previous studies have shown conflicting results...
Contact allergy to allergens of the TRUE-test (panels 1 and 2) has decreased modestly in the general populationJ P Thyssen
National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark
Br J Dermatol 161:1124-9. 2009..The prevalence of contact allergy in the general population is nearly 20%...
No association between nickel allergy and reporting cosmetic dermatitis from mascara or eye shadow: a cross-sectional general population studyJ P Thyssen
National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
J Eur Acad Dermatol Venereol 24:722-5. 2010..However, an association between nickel eyelid dermatitis and nickel in make-up products remains controversial...
The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the handsS Heydorn
Department of Dermatology, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Contact Dermatitis 48:324-30. 2003....
The prevalence and morbidity of sensitization to fragrance mix I in the general populationJ P Thyssen
National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, Hellerup 2900, Denmark
Br J Dermatol 161:95-101. 2009..The prevalence of sensitization to fragrance mix (FM) I and Myroxylon pereirae (MP, balsam of Peru) has decreased in recent years among Danish women with dermatitis...
A stronger patch test elicitation reaction to the allergen hydroxycitronellal plus the irritant sodium lauryl sulfateS Heydorn
Department of Dermatology, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Contact Dermatitis 49:133-9. 2003..0253). Estimation of the blood flow with laser Doppler supported these findings...
Hand eczema in twins: a questionnaire investigationL E Bryld
Department of Dermatology, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Br J Dermatol 142:298-305. 2000..The relevance of known individual risk factors such as atopic dermatitis or contact allergy in relation to heredity remains to be analysed. The possible importance of age and temporal change also needs further consideration...
The effect of tobacco smoking and alcohol consumption on the prevalence of self-reported hand eczema: a cross-sectional population-based studyJ P Thyssen
National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Hellerup, Gentofte, Denmark
Br J Dermatol 162:619-26. 2010..It has been debated whether life-style factors such as tobacco smoking and alcohol consumption are associated with hand eczema...
Individuals who are homozygous for the 2282del4 and R501X filaggrin null mutations do not always develop dermatitis and complete long-term remission is possibleJ P Thyssen
National Allergy Research Centre, Department of Dermato Allergology, Gentofte Hospital, University of Copenhagen, Denmark
J Eur Acad Dermatol Venereol 26:386-9. 2012..No studies have investigated whether individuals with the homozygous filaggrin null genotype always develop dermatitis...
Hydroxyisohexyl 3-cyclohexene carboxaldehyde- known as Lyral: quantitative aspects and risk assessment of an important fragrance allergenJ D Johansen
National Allergy Research Centre, Department of Dermatology, Gentofte Hospital, University of Copenhagen, Gentofte, Denmark
Contact Dermatitis 48:310-6. 2003..The same levels were shown to elicit allergic contact dermatitis in almost all sensitized individuals. A significant reduction in usage concentrations is recommended to prevent contact allergic reactions...
Fragrance allergy and hand eczema - a reviewS Heydorn
Department of Dermatology, Gentofte Hospital, University of Copenhagen, Denmark
Contact Dermatitis 48:59-66. 2003..As exposures to fragrances on the hands are often simultaneous exposures to irritants, this combined exposure approach needs to be considered...
Contact dermatitis to hair dyes in a Danish adult population: an interview-based studyH Søsted
The National Allergy Research Centre, Department of Dermatology, University of Copenhagen, Gentofte Hospital, Copenhagen, Denmark
Br J Dermatol 153:132-5. 2005..Surveys show that consumers with even severe adverse skin reactions to hair dyes only rarely contact the healthcare services. The frequency of hair dye-induced skin reactions in the consumer population is unknown...
The prevalence of chromium allergy in Denmark is currently increasing as a result of leather exposureJ P Thyssen
Department of Dermato Allergology, National Allergy Research Centre, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Br J Dermatol 161:1288-93. 2009..An effect from this intervention has previously been demonstrated among Danish construction workers...
Citral a fragrance allergen and irritantS Heydorn
Department of Dermatology, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Contact Dermatitis 49:32-6. 2003..The difference regarding fragrance history found between those with IR and positive reactions to citral was not significant. Citral could be an allergen and/or irritant, worthy of further more extensive studies...
Hydroxyisohexyl 3-cyclohexene carboxaldehyde allergy: relationship between patch test and repeated open application test thresholdsL A Fischer
Department of Dermato Allergology, The National Allergy Research Centre, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark
Br J Dermatol 161:560-7. 2009..Fragrance ingredients are special as significant amounts of allergen may evaporate from the skin...
The association between null mutations in the filaggrin gene and contact sensitization to nickel and other chemicals in the general populationJ P Thyssen
National Allergy Research Centre, Department of Dermato Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark
Br J Dermatol 162:1278-85. 2010....
Allergic contact dermatitis from methyldibromo glutaronitrile--clinical cases from 2003C Zachariae
Department of Dermatology, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark
Contact Dermatitis 52:6-8. 2005..p.m. to 473 p.p.m. MDBGN in products used by the patients. Based on the present clinical study and accumulated evidence in the literature, it is concluded that MDBGN is not suitable for use in any type of cosmetic product...
Methyldibromoglutaronitrile allergy: relationship between patch test and repeated open application test thresholdsL A Fischer
The National Allergy Research Centre, Department of Dermatology, University of Copenhagen, Gentofte Hospital, Ledreborg Alle 40, 2820 Gentofte, Denmark
Br J Dermatol 159:1138-43. 2008..Experimental studies with other allergens have shown a significant relationship between the patch test and the repeated open application test (ROAT) reactivity...
Nickel allergy: relationship between patch test and repeated open application test thresholdsL A Fischer
The National Allergy Research Centre, Department of Dermatology, University of Copenhagen, Gentofte Hospital, Ledreborg Alle 40, 2820 Gentofte, Denmark
Br J Dermatol 157:723-9. 2007..Exposure regulation has proven effective in decreasing the frequency. Experimental studies with other allergens have shown a significant relation between patch test reactivity and repeated open application test (ROAT) reactivity...
Nickel-induced activation of T cells in individuals with negative patch test to nickel sulphateS Lisby
Department of Dermatology, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark
Arch Dermatol Res 291:247-52. 1999..Thus, at this level, no qualitative differences could be demonstrated between T cells obtained from nickel-allergic and nonallergic individuals...
Filaggrin null alleles are not associated with hand eczema or contact allergyA Lerbaek
National Allergy Research Centre, Gentofte Hospital, University of Copenhagen, Ledreborg Alle 40, 1, 2820 Gentofte, Denmark
Br J Dermatol 157:1199-204. 2007..The variant alleles have repeatedly been shown to be associated with atopic dermatitis. Any possible association with hand eczema or contact allergy are unexplored...
Incidence of hand eczema in a population-based twin cohort: genetic and environmental risk factorsA Lerbaek
National Allergy Research Centre, Gentofte Hospital, University of Copenhagen, Ledreborg Alle 40, 1, 2820 Gentofte, Denmark
Br J Dermatol 157:552-7. 2007..Population-based studies on the incidence of hand eczema are sparse...
Incidence of allergic contact sensitization in Danish adults between 1990 and 1998; the Copenhagen Allergy Study, DenmarkN H Nielsen
Department of Dermatology K, Gentofte Hospital, University of Copenhagen, 65, Niels Andersens Vej, DK 2900 Hellerup, Denmark
Br J Dermatol 147:487-92. 2002..Studies of incidence of contact allergy in a general population have not been reported. Data from incidence studies may support and direct strategies for prevention of contact allergy and allergic contact dermatitis...
Experimental elicitation of contact allergy from a diazolidinyl urea-preserved cream in relation to anatomical region, exposure time and concentrationClaus Zachariae
Department of Dermatology, University Clinic Gentofte, University of Copenhagen, Copenhagen, Denmark
Contact Dermatitis 53:268-77. 2005..A clear dose-response relationship was seen regarding preservative concentration in the product...
Inverse relationship between allergic contact dermatitis and type 1 diabetes mellitus: a retrospective clinic-based studyK Engkilde
National Allergy Research Centre, Department of Dermatology, Gentofte Hospital, University of Copenhagen, DK 2820, Copenhagen, Denmark
Diabetologia 49:644-7. 2006..To investigate whether environmental exposure to chemicals leading to CA could influence the risk of type 1 diabetes, we conducted a retrospective clinic-based study of patients subjected to diagnostic patch testing of CA...
Contact dermatitis from methylisothiazolinone in a paint factoryJ P Thyssen
Department of Dermato venerology, Gentofte Hospital, University of Copenhagen, Niels Andersensvej 65, 2900 Hellerup, Denmark
Contact Dermatitis 54:322-4. 2006..Our data show that MI holds a potential for eliciting and propably inducing contact allergy in humans. Whether this preservative is safe to use in cosmetics where billions of consumers are exposed needs a care full monitoring...
Treatment of hand eczemaN K Veien
Department of Dermatology, University of Copenhagen, Gentofte Hospital, Copenhagen, Denmark
Skin Therapy Lett 8:4-7. 2003..Botulinum toxin has been used with success in the treatment of dyshidrotic hand eczema. PUVA is effective as a systemic treatment. Bath-PUVA treatment, UVB and Grenz rays can also suppress hand eczema...
Decrease in nickel sensitization in a Danish schoolgirl population with ears pierced after implementation of a nickel-exposure regulationChristian Stab Jensen
Department of Dermatology, Gentofte Hospital, University of Copenhagen, Niels Andersensvej 65, DK 2900 Hellerup, Denmark
Br J Dermatol 146:636-42. 2002..To reduce the skin nickel exposure of the population, the Danish Ministry of Environment issued a regulation that was implemented in 1992, and the European Union countries have recently adopted an expanded regulation...
Effect of barrier perturbation on cutaneous salicylic acid penetration in human skin: in vivo pharmacokinetics using microdialysis and non-invasive quantification of barrier functionE Benfeldt
Department of Dermatology, University of Copenhagen, Gentofte Hospital, Niels Andersensvej 65, DK 2900 Hellerup, Denmark
Br J Dermatol 140:739-48. 1999..The measured drug penetration was demonstrated to correlate with non-invasive quantification of barrier damage...
