Ole Bjarne Christiansen

Summary

Affiliation: H:S Rigshospitalet
Country: Denmark

Publications

  1. ncbi [Pregnancy--an immunological challenge]
    Ole Bjarne Christiansen
    Fertilitetsklinikken 4071, H:S Rigshospitalet,
    Ugeskr Laeger 165:4379-81. 2003
  2. ncbi Impact of the sex of first child on the prognosis in secondary recurrent miscarriage
    O B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Hum Reprod 19:2946-51. 2004
  3. ncbi Evidence-based investigations and treatments of recurrent pregnancy loss
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen, Denmark
    Curr Opin Obstet Gynecol 18:304-12. 2006
  4. ncbi Research methodology and epidemiology of relevance in recurrent pregnancy loss
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen, Denmark
    Semin Reprod Med 24:5-16. 2006
  5. ncbi Evidence-based investigations and treatments of recurrent pregnancy loss
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Fertil Steril 83:821-39. 2005
  6. ncbi Active or passive immunization in unexplained recurrent miscarriage
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Reprod Immunol 62:41-52. 2004
  7. ncbi Mannose-binding lectin-2 genotypes and recurrent late pregnancy losses
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Hum Reprod 24:291-9. 2009
  8. ncbi Inflammation and miscarriage
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Semin Fetal Neonatal Med 11:302-8. 2006
  9. ncbi The impact of anti-HY responses on outcome in current and subsequent pregnancies of patients with recurrent pregnancy losses
    Ole Bjarne Christiansen
    The Fertility Clinic 4071, University Hospital Copenhagen, Rigshospitalet, DK 2100 Copenhagen, Denmark
    J Reprod Immunol 85:9-14. 2010
  10. ncbi The presence of HLA-antibodies in recurrent miscarriage patients is associated with a reduced chance of a live birth
    Henriette Svarre Nielsen
    The Fertility Clinic, University Hospital Copenhagen, Rigshospitalet, Fertility Clinic 4071, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Reprod Immunol 87:67-73. 2010

Detail Information

Publications24

  1. ncbi [Pregnancy--an immunological challenge]
    Ole Bjarne Christiansen
    Fertilitetsklinikken 4071, H:S Rigshospitalet,
    Ugeskr Laeger 165:4379-81. 2003
  2. ncbi Impact of the sex of first child on the prognosis in secondary recurrent miscarriage
    O B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Hum Reprod 19:2946-51. 2004
    ..The carriage of a male fetus often initiates maternal immunological reactions against male-specific minor histocompatibility (HY) antigens, which, in theory, could result in subsequent recurrent miscarriage (RM)...
  3. ncbi Evidence-based investigations and treatments of recurrent pregnancy loss
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen, Denmark
    Curr Opin Obstet Gynecol 18:304-12. 2006
    ..In this review a critical analysis is given of the current management of recurrent pregnancy loss often recommended in meta-analyses and guidelines...
  4. ncbi Research methodology and epidemiology of relevance in recurrent pregnancy loss
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen, Denmark
    Semin Reprod Med 24:5-16. 2006
    ..Advice is given about to how to avoid the pitfalls in order that the validity of the studies can improve for the benefit of the patients...
  5. ncbi Evidence-based investigations and treatments of recurrent pregnancy loss
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Fertil Steril 83:821-39. 2005
    ..To give an overview of currently used investigations and treatments offered to women with recurrent pregnancy loss (RPL) and, from an evidence-based point of view, to evaluate the usefulness of these interventions...
  6. ncbi Active or passive immunization in unexplained recurrent miscarriage
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Reprod Immunol 62:41-52. 2004
    ..Furthermore, treated patients should be extensively monitored for changes in a series of immune parameters that may predict pregnancy success and be of importance for our understanding of the mechanisms of action of immunotherapy in RM...
  7. ncbi Mannose-binding lectin-2 genotypes and recurrent late pregnancy losses
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Hum Reprod 24:291-9. 2009
    ..Recurrent late pregnancy losses (RLPL) in the second trimester is a rare but devastating syndrome where maternal rather than fetal causes are likely to play a stronger role than in early recurrent miscarriage...
  8. ncbi Inflammation and miscarriage
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Semin Fetal Neonatal Med 11:302-8. 2006
    ....
  9. ncbi The impact of anti-HY responses on outcome in current and subsequent pregnancies of patients with recurrent pregnancy losses
    Ole Bjarne Christiansen
    The Fertility Clinic 4071, University Hospital Copenhagen, Rigshospitalet, DK 2100 Copenhagen, Denmark
    J Reprod Immunol 85:9-14. 2010
    ..We propose pathogenetic pathways for these conditions that in our view best explain the findings...
  10. ncbi The presence of HLA-antibodies in recurrent miscarriage patients is associated with a reduced chance of a live birth
    Henriette Svarre Nielsen
    The Fertility Clinic, University Hospital Copenhagen, Rigshospitalet, Fertility Clinic 4071, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Reprod Immunol 87:67-73. 2010
    ..The presence of these antibodies in early pregnancy is associated with a reduced chance of a live birth. Further exploring this association may increase our understanding of maternal acceptance of the fetal allograft...
  11. ncbi Sex of prior children and risk of stillbirth in subsequent pregnancies
    Henriette Svarre Nielsen
    The National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark
    Epidemiology 21:114-7. 2010
    ..Delivery of a boy has been reported to increase a woman's risk of recurrent miscarriage in subsequent pregnancies. We explored whether delivery of boys similarly increases the risk of a subsequent stillbirth...
  12. ncbi Association of HY-restricting HLA class II alleles with pregnancy outcome in patients with recurrent miscarriage subsequent to a firstborn boy
    Henriette Svarre Nielsen
    The Fertility Clinic, University Hospital Copenhagen, Rigshospitalet, Denmark
    Hum Mol Genet 18:1684-91. 2009
    ..The results may shed light on the as-yet unknown immunological causes of SRM and may help understand the successful maternal acceptance of the fetal semi-allograft...
  13. ncbi A firstborn boy is suggestive of a strong prognostic factor in secondary recurrent miscarriage: a confirmatory study
    Henriette Svarre Nielsen
    The Fertility Clinic, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Fertil Steril 89:907-11. 2008
    ..To test our previously generated hypothesis that women with secondary recurrent miscarriages with a firstborn boy have a poorer pregnancy prognosis than those with a firstborn girl...
  14. ncbi Anti-HY responses in pregnancy disorders
    Ole Bjarne Christiansen
    The Fertility Clinic 4071, University Hospital Copenhagen, Rigshospitalet, Copenhagen, Denmark
    Am J Reprod Immunol 66:93-100. 2011
    ..However, the importance of these responses for pregnancy outcome is unclear...
  15. ncbi Brothers and reduction of the birth weight of later-born siblings
    Henriette Svarre Nielsen
    The National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark
    Am J Epidemiol 167:480-4. 2008
    ..An explanation for these results could be maternal immune reactions directed against the H-Y antigens initiated during pregnancies with boys. The findings might add to the understanding of both normal and pathologic pregnancies...
  16. ncbi Prognosis for live birth in women with recurrent miscarriage: what is the best measure of success?
    Marie Lund
    The Fertility Clinic, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Obstet Gynecol 119:37-43. 2012
    ..To establish a method of estimating the proportion of women with a subsequent live birth after a well-defined time period in an open cohort of women referred to a tertiary recurrent miscarriage clinic...
  17. ncbi Future directions of failed implantation and recurrent miscarriage research
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Reprod Biomed Online 13:71-83. 2006
    ....
  18. ncbi Linkage disequilibrium between human leukocyte antigen (HLA) class II and HLA-G--possible implications for human reproduction and autoimmune disease
    Thomas Vauvert F Hviid
    Department of Clinical Biochemistry, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Hum Immunol 66:688-99. 2005
    ..Implications of HLA polymorphism--and other polymorphic genes in the MHC for pregnancy outcome--and for autoimmune diseases during pregnancy are discussed...
  19. ncbi Prognostic impact of anticardiolipin antibodies in women with recurrent miscarriage negative for the lupus anticoagulant
    Henriette Svarre Nielsen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen University Hospital, Naestved, Copenhagen, Denmark
    Hum Reprod 20:1720-8. 2005
    ..This reduction is inferior to what has been reported from studies where no adjustments for prognostic variables were undertaken and LAC positive patients were included...
  20. ncbi Indications of anti-HY immunity in recurrent placental abruption
    Henriette Svarre Nielsen
    The Fertility Clinic 4071, University Hospital Copenhagen, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    J Reprod Immunol 75:63-9. 2007
    ..However, some recent reports point toward a maternal immune response against the fetus as a possible mechanism. No data exist concerning special characteristics of patients suffering recurrent placental abruptions...
  21. ncbi Intravenous immunoglobulin in the prevention of recurrent miscarriage: does it work?
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen, Denmark
    Chem Immunol Allergy 88:117-27. 2005
    ..A new large placebo-controlled trial should be conducted in RM patients with secondary RM or repeated second trimester fetal deaths and sufficient IvIg doses should be given with optimal timing...
  22. ncbi HLA-G and IL-10 in serum in relation to HLA-G genotype and polymorphisms
    Thomas Vauvert F Hviid
    Department of Clinical Biochemistry, Copenhagen University Hospital, Rigshospitalet, Denmark
    Immunogenetics 56:135-41. 2004
    ..In conclusion, this study indicates that polymorphisms in the 3'UTR and the 5'URR of the HLA-G gene may influence the expression of sHLA-G of possible importance in pathological pregnancies and also in organ transplantation...
  23. ncbi Study of the structure and impact of human leukocyte antigen (HLA)-G-A, HLA-G-B, and HLA-G-DRB1 haplotypes in families with recurrent miscarriage
    Astrid M Kolte
    Fertility Clinic 4071, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Hum Immunol 71:482-8. 2010
    ....
  24. ncbi Multifactorial etiology of recurrent miscarriage and its scientific and clinical implications
    Ole B Christiansen
    Fertility Clinic 4071, Rigshospitalet, Copenhagen, Denmark
    Gynecol Obstet Invest 66:257-67. 2008
    ..Acknowledgement of the multifactorial background for RM has important implications for the management of patients in clinical practice...