Birgitte V Offersen

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. ncbi Matrix metalloproteinase-9 measured in urine from bladder cancer patients is an independent prognostic marker of poor survival
    Birgitte V Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark
    Acta Oncol 49:1283-7. 2010
  2. ncbi Accelerated partial breast irradiation as part of breast conserving therapy of early breast carcinoma: a systematic review
    Birgitte V Offersen
    Department of Oncology, Aarhus University Hospital, Aarhus C, Denmark
    Radiother Oncol 90:1-13. 2009
  3. ncbi Lack of association between level of Plasminogen Activator Inhibitor-1 and estimates of tumor angiogenesis in early breast cancer
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus C, Denmark
    Acta Oncol 46:782-91. 2007
  4. ncbi Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer: relation to prognosis and angiogenesis
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Nørrebrogade 44, Bld 5, DK 8000 Aarhus C, Denmark
    Lung Cancer 56:43-50. 2007
  5. ncbi Chalkley estimates of angiogenesis in early breast cancer--relevance to prognosis
    Birgitte V Offersen
    Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark
    Acta Oncol 41:695-703. 2002
  6. ncbi The prognostic relevance of estimates of proliferative activity in early breast cancer
    B V Offersen
    Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus, Denmark
    Histopathology 43:573-82. 2003
  7. ncbi The myofibroblast is the predominant plasminogen activator inhibitor-1-expressing cell type in human breast carcinomas
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Nørrebrogade 44, Building 5, DK 8000 Aarhus C, Denmark
    Am J Pathol 163:1887-99. 2003
  8. ncbi Quantification of angiogenesis as a prognostic marker in human carcinomas: a critical evaluation of histopathological methods for estimation of vascular density
    B V Offersen
    Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus University Hospital, Nørrebrogade 44, Bld 5, DK 8000 Aarhus C, Denmark
    Eur J Cancer 39:881-90. 2003
  9. ncbi Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis
    B V Offersen
    Department of Experimental Clinical Oncology, Danish Cancer Society, Aarhus University Hospital, Noerrebrogade 44, Bldg 5, DK 8000 Aarhus C, Denmark
    Br J Cancer 87:1422-30. 2002
  10. ncbi Comparison of methods of microvascular staining and quantification in prostate carcinoma: relevance to prognosis
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, University Hospital of Aarhus, Denmark
    APMIS 110:177-85. 2002

Detail Information

Publications15

  1. ncbi Matrix metalloproteinase-9 measured in urine from bladder cancer patients is an independent prognostic marker of poor survival
    Birgitte V Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark
    Acta Oncol 49:1283-7. 2010
    ..The prognostic value of these measurements has never been investigated. Using this assay we have investigated the prognostic influence of total and active MMP-9 in urine from bladder cancer patients...
  2. ncbi Accelerated partial breast irradiation as part of breast conserving therapy of early breast carcinoma: a systematic review
    Birgitte V Offersen
    Department of Oncology, Aarhus University Hospital, Aarhus C, Denmark
    Radiother Oncol 90:1-13. 2009
    ..Patient selection for this therapy is pivotal and based on evidence from previous studies on patient/tumour characteristics and pattern of local recurrences we propose inclusion criteria for patients in APBI protocols...
  3. ncbi Lack of association between level of Plasminogen Activator Inhibitor-1 and estimates of tumor angiogenesis in early breast cancer
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus C, Denmark
    Acta Oncol 46:782-91. 2007
    ..This study confirms high PAI-1 or high Chalkley counts as markers of poor prognosis in breast cancer patients, and suggests that the prognostic impact of PAI-1 is independent of its supposed involvement in tumor angiogenesis...
  4. ncbi Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer: relation to prognosis and angiogenesis
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Nørrebrogade 44, Bld 5, DK 8000 Aarhus C, Denmark
    Lung Cancer 56:43-50. 2007
    ..We investigate whether uPA and PAI-1 are prognostic markers in NSCLC and whether they are related to angiogenesis...
  5. ncbi Chalkley estimates of angiogenesis in early breast cancer--relevance to prognosis
    Birgitte V Offersen
    Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark
    Acta Oncol 41:695-703. 2002
    ..Thus, in a univariate analysis it was found that high Chalkley estimates of angiogenesis indicated a poor prognosis, but high Chalkley estimates were independent prognostic markers only in node-positive patients...
  6. ncbi The prognostic relevance of estimates of proliferative activity in early breast cancer
    B V Offersen
    Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus, Denmark
    Histopathology 43:573-82. 2003
    ..This study investigates whether MIB-1 scores add additional prognostic impact when evaluated together with classical clinicopathological parameters at diagnosis in early breast cancer patients...
  7. ncbi The myofibroblast is the predominant plasminogen activator inhibitor-1-expressing cell type in human breast carcinomas
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Nørrebrogade 44, Building 5, DK 8000 Aarhus C, Denmark
    Am J Pathol 163:1887-99. 2003
    ..In conclusion, we have provided a robust immunohistochemical procedure for detection of PAI-1 and shown that the majority of the PAI-1-expressing cells in invasive ductal breast carcinomas are myofibroblasts...
  8. ncbi Quantification of angiogenesis as a prognostic marker in human carcinomas: a critical evaluation of histopathological methods for estimation of vascular density
    B V Offersen
    Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus University Hospital, Nørrebrogade 44, Bld 5, DK 8000 Aarhus C, Denmark
    Eur J Cancer 39:881-90. 2003
    ....
  9. ncbi Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis
    B V Offersen
    Department of Experimental Clinical Oncology, Danish Cancer Society, Aarhus University Hospital, Noerrebrogade 44, Bldg 5, DK 8000 Aarhus C, Denmark
    Br J Cancer 87:1422-30. 2002
    ..In conclusion, inflammation was significantly correlated to microvessel density, and areas of intense inflammation were an independent marker of good prognosis...
  10. ncbi Comparison of methods of microvascular staining and quantification in prostate carcinoma: relevance to prognosis
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, University Hospital of Aarhus, Denmark
    APMIS 110:177-85. 2002
    ..In conclusion, anti-CD34 antibodies are sensitive endothelial markers in prostate carcinoma, and the investigated counting methods are compatible. Moreover, high vascular scores seem to carry a poor prognosis...
  11. ncbi Patterns of angiogenesis in nonsmall-cell lung carcinoma
    B V Offersen
    Danish Cancer Society, Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark
    Cancer 91:1500-9. 2001
    ....
  12. ncbi Vitronectin in human breast carcinomas
    Mads Aaboe
    Laboratory for Cellular Protein Science, Department for Molecular Biology, Aarhus University, Gustav Wied s Vej 10C, DK 8000 C, Aarhus, Denmark
    Biochim Biophys Acta 1638:72-82. 2003
    ....
  13. ncbi Microvessel density predicts survival in prostate cancer patients subjected to watchful waiting
    M Borre
    The Danish Cancer Society, Department of Experimental Clinical Oncology, University Hospital of Aarhus
    Br J Cancer 78:940-4. 1998
    ..0004), as well as in the clinically localized cancer population (P < 0.0001). These findings suggest that quantitation of angiogenesis reflects the spontaneous clinical outcome of prostate cancer...
  14. ncbi A comparison among HER2, TP53, PAI-1, angiogenesis, and proliferation activity as prognostic variables in tumours from 408 patients diagnosed with early breast cancer
    Birgitte Vrou Offersen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark
    Acta Oncol 47:618-32. 2008
    ..One hundred and sixty seven patients (41%) died from breast cancer...
  15. ncbi A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients
    Jan Alsner
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark
    Acta Oncol 47:600-7. 2008
    ..To clarify their interrelationship and the importance of different TP53 mutation types, these markers were investigated in tumours from 630 patients with breast cancer...