Research Topics
| Hans Jurgen HoffmannSummaryAffiliation: Aarhus University Hospital Country: Denmark Publications
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Detail Information
Publications
Cultured human mast cells are heterogeneous for expression of the high-affinity IgE receptor Fc?RIHans Jurgen Hoffmann
Department of Respiratory Diseases, Aarhus University and Hospital, Aarhus, Denmark
Int Arch Allergy Immunol 157:246-50. 2012..We determined the density of Fc?RI on mast cells cultured from cord (CBMC) and peripheral blood (PBMC) and studied the kinetics of the response through Fc?RI...
Human skin keratins are the major proteins in exhaled breath condensateH J Hoffmann
Dept of Respiratory Diseases, Aarhus University Hospital, Denmark
Eur Respir J 31:380-4. 2008..Filtration of inspired air did not remove contaminating keratin. In conclusion, skin keratin in exhaled breath condensate derives from ambient air and not from the respiratory tract...
Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapySusan Mikkelsen
Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark
Clin Mol Allergy 8:2. 2010..Expression of CD203c was compared to CD63 as marker for basophil activation, using a Bland Altman plot and ROC curves...
Comparison of short term in vitro cultured human mast cells from different progenitors - Peripheral blood-derived progenitors generate highly mature and functional mast cellsHanne Busk Andersen
Department of Paediatrics, Aarhus University Hospital, DK 8200 Aarhus N, Denmark
J Immunol Methods 336:166-74. 2008..Cord and peripheral blood may give rise to different types of MC. The question addressed should determine the progenitor cell and protocol to be used...
Seven week culture of functional human mast cells from buffy coat preparationsMette Holm
Department of Human Genetics, University of Aarhus, DK 8000 Aarhus C, Denmark
J Immunol Methods 336:213-21. 2008..g. bone marrow or cord blood-derived progenitors. Consequently, our protocol has great potential in studies on mast cell biology and mast cell pathology, and e.g. on evaluation of drug effects...
A single exposure to organic dust of non-naïve non-exposed volunteers induces long-lasting symptoms of endotoxin toleranceHans Jurgen Hoffmann
Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Germany
Int Arch Allergy Immunol 138:121-6. 2005..Endotoxin tolerance has previously been described in vitro and animal studies as a mechanism that modifies the threshold at which response occurs...
Response of respiratory flour allergics in an ingested flour challenge may involve plasmacytoid dendritic cells, CD25+ and CD152+ T cellsHans Jurgen Hoffmann
Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark
Int Arch Allergy Immunol 140:252-60. 2006..A number of occupational respiratory allergens are food related, and little is known about the responses these allergens elicit in sensitized persons that ingest them...
Psoriasin binds calcium and is upregulated by calcium to levels that resemble those observed in normal skinH J Hoffmann
Institute of Medical Biochemistry, Aarhus University, Denmark
J Invest Dermatol 103:370-5. 1994..56) to levels that resemble those observed in unfractionated keratinocyte populations obtained from normal skin...
