N B Finnerup

Summary

Affiliation: Aarhus University Hospital
Country: Denmark

Publications

  1. ncbi Intravenous lidocaine relieves spinal cord injury pain: a randomized controlled trial
    Nanna B Finnerup
    Department of Neurology and Danish Pain Research Center, Aarhus Sygehus, Aarhus, Denmark
    Anesthesiology 102:1023-30. 2005
  2. ncbi Algorithm for neuropathic pain treatment: an evidence based proposal
    N B Finnerup
    Department of Neurology, Danish Pain Research Centre, Aarhus University Hospital, Aarhus Sygehus, Noerrebrogade 44, Aarhus 8000, Denmark
    Pain 118:289-305. 2005
  3. ncbi Spinal cord injury pain--mechanisms and treatment
    N B Finnerup
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Eur J Neurol 11:73-82. 2004
  4. ncbi MRI in chronic spinal cord injury patients with and without central pain
    N B Finnerup
    Department of Neurology and Danish Pain Research Centre, Aarhus University Hospital, Denmark
    Neurology 61:1569-75. 2003
  5. ncbi Mechanisms of disease: mechanism-based classification of neuropathic pain-a critical analysis
    Nanna B Finnerup
    Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    Nat Clin Pract Neurol 2:107-15. 2006
  6. ncbi Sensory function in spinal cord injury patients with and without central pain
    N B Finnerup
    Department of Neurology and Danish Pain Research Centre, Aarhus University Hospital, Denmark
    Brain 126:57-70. 2003
  7. ncbi Anticonvulsants in central pain
    Nanna B Finnerup
    Department of Neurology and Danish Pain Research Centre, Aarhus University Hospital, Noerrebrogade 44, 8000 Aarhus C, Denmark
    Expert Opin Pharmacother 3:1411-20. 2002
  8. ncbi Lamotrigine in spinal cord injury pain: a randomized controlled trial
    Nanna B Finnerup
    Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, Arhus, Denmark
    Pain 96:375-83. 2002
  9. ncbi Levetiracetam in spinal cord injury pain: a randomized controlled trial
    N B Finnerup
    Danish Pain Research Center, University of Aarhus, Aarhus, Denmark
    Spinal Cord 47:861-7. 2009
  10. ncbi Pain and dysesthesia in patients with spinal cord injury: A postal survey
    N B Finnerup
    Department of Neurology and Danish Pain Research Centre, University Hospital of Aarhus, Denmark
    Spinal Cord 39:256-62. 2001

Detail Information

Publications30

  1. ncbi Intravenous lidocaine relieves spinal cord injury pain: a randomized controlled trial
    Nanna B Finnerup
    Department of Neurology and Danish Pain Research Center, Aarhus Sygehus, Aarhus, Denmark
    Anesthesiology 102:1023-30. 2005
    ..The current study examines the analgesic effect of the sodium channel blocker lidocaine on neuropathic pain in patients with spinal cord injury and the predictive role of concomitant evoked pain on pain relief with lidocaine...
  2. ncbi Algorithm for neuropathic pain treatment: an evidence based proposal
    N B Finnerup
    Department of Neurology, Danish Pain Research Centre, Aarhus University Hospital, Aarhus Sygehus, Noerrebrogade 44, Aarhus 8000, Denmark
    Pain 118:289-305. 2005
    ....
  3. ncbi Spinal cord injury pain--mechanisms and treatment
    N B Finnerup
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Eur J Neurol 11:73-82. 2004
    ..SCI neuropathic pain is difficult to treat. Experimental and human randomized, double-blind, placebo-controlled, clinical trials on pharmacologic treatment of SCI pain are summarized...
  4. ncbi MRI in chronic spinal cord injury patients with and without central pain
    N B Finnerup
    Department of Neurology and Danish Pain Research Centre, Aarhus University Hospital, Denmark
    Neurology 61:1569-75. 2003
    ..Central pain following spinal cord injury (SCI) is common and thought to be related to lesion of the spinothalamic pathways...
  5. ncbi Mechanisms of disease: mechanism-based classification of neuropathic pain-a critical analysis
    Nanna B Finnerup
    Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    Nat Clin Pract Neurol 2:107-15. 2006
    ....
  6. ncbi Sensory function in spinal cord injury patients with and without central pain
    N B Finnerup
    Department of Neurology and Danish Pain Research Centre, Aarhus University Hospital, Denmark
    Brain 126:57-70. 2003
    ..These data suggest that lesion of the spinothalamic pathway alone cannot account for central pain in SCI patients, and that neuronal hyperexcitability at injury or higher level may be an important mechanism for pain below injury level...
  7. ncbi Anticonvulsants in central pain
    Nanna B Finnerup
    Department of Neurology and Danish Pain Research Centre, Aarhus University Hospital, Noerrebrogade 44, 8000 Aarhus C, Denmark
    Expert Opin Pharmacother 3:1411-20. 2002
    ..Present suggestions for anticonvulsant treatment of CP are lamotrigine as the first choice, followed by gabapentin or carbamazepine/oxcarbazepine. These compounds are considered as effective as the antidepressant amitriptyline...
  8. ncbi Lamotrigine in spinal cord injury pain: a randomized controlled trial
    Nanna B Finnerup
    Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, Arhus, Denmark
    Pain 96:375-83. 2002
    ....
  9. ncbi Levetiracetam in spinal cord injury pain: a randomized controlled trial
    N B Finnerup
    Danish Pain Research Center, University of Aarhus, Aarhus, Denmark
    Spinal Cord 47:861-7. 2009
    ..A 1-week baseline period was followed by two treatment periods of 5 weeks duration with levetiracetam increased from 500 mg b.i.d. to a maximum of 1500 mg b.i.d. separated by a 1-week washout period...
  10. ncbi Pain and dysesthesia in patients with spinal cord injury: A postal survey
    N B Finnerup
    Department of Neurology and Danish Pain Research Centre, University Hospital of Aarhus, Denmark
    Spinal Cord 39:256-62. 2001
    ..Unexpectedly, only 7% of the patients were treated with drugs considered to be most effective in neuropathic pain. This emphasizes the need for a continued research and education on P/D in SCI...
  11. ncbi Sensory perception in complete spinal cord injury
    N B Finnerup
    Departments of Neurology and Danish Pain Research Centre Neuroradiology Clinical Neurophysiology, Aarhus University Hospital, Aarhus, Denmark
    Acta Neurol Scand 109:194-9. 2004
    ..SEP and MRI did not differentiate between these two groups. CONCLUSION: The present study suggests retained sensory communication across the injury in complete SCI, i.e. 'sensory discomplete' SCI...
  12. ncbi Sensory function above lesion level in spinal cord injury patients with and without pain
    N B Finnerup
    Department of Neurology and Danish Pain Research Centre, Aarhus University Hospital, Denmark
    Somatosens Mot Res 20:71-6. 2003
    ..The results are discussed in relation to current concepts of pain inhibitory and facilitating systems...
  13. ncbi The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study
    Lise Gormsen
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Norrebrogade 44, Building 1A, DK 8000 Aarhus C, Denmark
    Anesth Analg 108:1311-9. 2009
    ....
  14. ncbi Abdominal pain in long-term spinal cord injury
    N B Finnerup
    Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    Spinal Cord 46:198-203. 2008
    ..To describe the prevalence and character of chronic abdominal pain in a group of patients with long-term spinal cord injury (SCI) and to assess predictors of abdominal pain...
  15. ncbi Chronic neuropathic pain: mechanisms, drug targets and measurement
    Nanna B Finnerup
    Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, DK 8000 Aarhus, Denmark
    Fundam Clin Pharmacol 21:129-36. 2007
    ..The present review summarizes mechanisms of neuropathic pain, targets of currently used drugs, and measures used in neuropathic pain trials...
  16. ncbi A review of central neuropathic pain states
    Nanna B Finnerup
    Danish Pain Research Center, Aarhus University Hospital, and the Spinal Cord Unit, Viborg Hospital, Denmark
    Curr Opin Anaesthesiol 21:586-9. 2008
    ..The present review highlights recent advances in the understanding of the underlying mechanisms and in the diagnosis and treatment of central pain...
  17. ncbi Reaction to topical capsaicin in spinal cord injury patients with and without central pain
    Nanna B Finnerup
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Norrebrogade 44, DK 8000 Aarhus, Denmark
    Exp Neurol 205:190-200. 2007
    ..04) but not an increased response to capsaicin in patients with central pain. These results suggest that SCI patients with below-level pain have increased responses to some but not all sensory input at the level of injury...
  18. ncbi Pharmacology and treatment of neuropathic pains
    Troels S Jensen
    Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    Curr Opin Neurol 22:467-74. 2009
    ..This review briefly discusses the definition and clinical presentation of neuropathic pain and highlights recent advances in the treatment of neuropathic pain...
  19. ncbi Antidepressants in the treatment of neuropathic pain
    Søren H Sindrup
    Department of Neurology, Odense University Hospital, DK 5000 Odense, Denmark
    Basic Clin Pharmacol Toxicol 96:399-409. 2005
    ..However, without head-to-head comparisons between antidepressants and other analgesics, it is not possible to provide real evidence-based treatment algorithms for neuropathic pain...
  20. ncbi Pharmacological management of neuropathic pain following spinal cord injury
    Cathrine Baastrup
    Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    CNS Drugs 22:455-75. 2008
    ..Cannabinoids have been found to relieve other types of central pain, and serotonin noradrenaline reuptake inhibitors as well as opioids relieve peripheral neuropathic pain and may be used to treat patients with SCI pain...
  21. ncbi Pain, referred sensations, and involuntary muscle movements in brachial plexus injury
    Nanna B Finnerup
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Acta Neurol Scand 121:320-7. 2010
    ..Examination of the relationship between pain, sensory hypersensitivity, referred sensations and involuntary muscle jerks in patients with brachial plexus injury...
  22. ncbi A randomized study of the effects of gabapentin on postamputation pain
    Lone Nikolajsen
    Danish Pain Research Center, Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark
    Anesthesiology 105:1008-15. 2006
    ..Pain after amputation is common but difficult to treat. Therefore, the authors examined whether postoperative treatment with gabapentin could reduce postamputation stump and phantom pain...
  23. ncbi Segmental hypersensitivity and spinothalamic function in spinal cord injury pain
    Nanna B Finnerup
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
    Exp Neurol 207:139-49. 2007
    ....
  24. ncbi Cold hyposensitivity after topical application of capsaicin in humans
    Mikkel G Callsen
    Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Norrebrogade 44, Aarhus, Denmark
    Exp Brain Res 191:447-52. 2008
    ..These results suggest a peripheral mediated decrease in cold sensation following TPRV1 receptor activation...
  25. ncbi Central post-stroke pain: clinical characteristics, pathophysiology, and management
    Henriette Klit
    Danish Pain Research Center, Aarhus University Hospital, Denmark
    Lancet Neurol 8:857-68. 2009
    ..Although treatment of CPSP is difficult, the most effective approaches are those that target the increased neuronal hyperexcitability...
  26. ncbi An evidence-based algorithm for the treatment of neuropathic pain
    Nanna B Finnerup
    Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    MedGenMed 9:36. 2007
    ..The purpose of this article is to discuss an evidence-based algorithm that can be implemented by the primary care physician in his/her daily clinical practice for the treatment of patients with neuropathic pain conditions...
  27. ncbi Clinical trial outcome in neuropathic pain: relationship to study characteristics
    Jennifer Katz
    Department of Psychology, State University of New York College at Geneseo, NY, USA
    Neurology 70:263-72. 2008
    ..It is unclear whether these trials were unsuccessful because the medications truly lack efficacy or whether characteristics of the trials compromised the demonstration of treatment benefits...
  28. ncbi Pharmacologic management of neuropathic pain: evidence-based recommendations
    Robert H Dworkin
    University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Pain 132:237-51. 2007
    ..Long-term studies, head-to-head comparisons between medications, studies involving combinations of medications, and RCTs examining treatment of central NP are lacking and should be a priority for future research...
  29. ncbi Pain after spinal cord injury: an evidence-based review for clinical practice and research. Report of the National Institute on Disability and Rehabilitation Research Spinal Cord Injury Measures meeting
    Thomas N Bryce
    Department of Rehabilitation Medicine, The Mount Sinai Medical Center, 5 East 98th Street, 6th Floor, Box 1240B, New York, NY 10021, USA
    J Spinal Cord Med 30:421-40. 2007
    ..To examine the reliability, validity, sensitivity, and practicality of various outcome measures for pain after spinal cord injury (SCI), and to provide recommendations for specific measures for use in clinical trials...
  30. ncbi Expansion of nociceptive withdrawal reflex receptive fields in spinal cord injured humans
    Ole K Andersen
    Center for Sensory Motor Interaction, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7, D3, Aalborg DK 9220, Denmark
    Clin Neurophysiol 115:2798-810. 2004
    ..In the present study, withdrawal reflex receptive field (RRF) was determined in complete SCI subjects (N=9)...