Riet Dams

Summary

Publications

  1. ncbi Quantitation of a de-fluorinated analogue of casopitant mesylate by normal-phase liquid chromatography/mass spectrometry
    Riet Dams
    Analytical Sciences, Chemical Development, GlaxoSmithKline, Via A Fleming 4, 37135 Verona, Italy
    Rapid Commun Mass Spectrom 24:2650-4. 2010
  2. ncbi Detection, identification and quantification of a new de-fluorinated impurity in casopitant mesylate drug substance during late phase development: an analytical challenge involving a multidisciplinary approach
    Lucilla Turco
    Analytical Chemistry, GlaxoSmithKline Medicines Research Centre, Via Fleming 4, 37135 Verona, Italy
    J Pharm Biomed Anal 54:67-73. 2011

Detail Information

Publications2

  1. ncbi Quantitation of a de-fluorinated analogue of casopitant mesylate by normal-phase liquid chromatography/mass spectrometry
    Riet Dams
    Analytical Sciences, Chemical Development, GlaxoSmithKline, Via A Fleming 4, 37135 Verona, Italy
    Rapid Commun Mass Spectrom 24:2650-4. 2010
    ..This work is an example of the need for selective and accurate methodology during the development of a new chemical entity in order to develop an appropriate control strategy for impurities to ultimately ensure patient safety...
  2. ncbi Detection, identification and quantification of a new de-fluorinated impurity in casopitant mesylate drug substance during late phase development: an analytical challenge involving a multidisciplinary approach
    Lucilla Turco
    Analytical Chemistry, GlaxoSmithKline Medicines Research Centre, Via Fleming 4, 37135 Verona, Italy
    J Pharm Biomed Anal 54:67-73. 2011
    ..The results obtained on the development batches of the drug substance were used by the project team to set up a suitable control strategy and ultimately to ensure patient safety and the progression of the project...