Research Topics
Species | P KrsekSummaryAffiliation: Charles University Country: Czech Republic Publications
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Publications
Life-saving epilepsy surgery for status epilepticus caused by cortical dysplasiaPavel Krsek
Department of Paediatric Neurology, Charles University, 2nd Medical School, Motol University Hospital, Prague, Czech Republic
Epileptic Disord 4:203-8. 2002..The aim of the report is to encourage considering surgery in selected patients suffering from medically intractable SE early in life...
Incomplete resection of focal cortical dysplasia is the main predictor of poor postsurgical outcomeP Krsek
Department of Pediatric Neurology, Charles University, Second Medical School, Motol University Hospital, V Uvalu 84, CZ 15006 Prague 5, Czech Republic
Neurology 72:217-23. 2009..Focal cortical dysplasia (FCD) is recognized as the major cause of focal intractable epilepsy in childhood. Various factors influencing postsurgical seizure outcome in pediatric patients with FCD have been reported...
Different features of histopathological subtypes of pediatric focal cortical dysplasiaPavel Krsek
Department of Pediatric Neurology, Charles University, Second Medical School, Motol University Hospital, Prague, Czech Republic
Ann Neurol 63:758-69. 2008..Several histopathological types of FCD are distinguished. The aim of the study was to define distinctive features of FCD subtypes...
Different presurgical characteristics and seizure outcomes in children with focal cortical dysplasia type I or IIPavel Krsek
Department of Pediatric Neurology, Charles University, Second Medical School, Motol Hospital, Prague, Czech Republic
Epilepsia 50:125-37. 2009..The aim of the study was to characterize differences between FCD type I and II with respect to imaging and EEG findings, clinical and neuropsychological presentations, and surgical outcome...
Successful epilepsy surgery with a resection contralateral to a suspected epileptogenic lesionPavel Krsek
Department of Pediatric Neurology, Charles University, Second Medical School, Motol Hospital, Prague, Czech Republic
Epileptic Disord 9:82-9. 2007..The contralateral lesion was reassessed as nonspecific enlargement of perivascular spaces. The patient has been seizure-free for more than two years.[Published with video sequences]...
Nonconvulsive status epilepticus in rats: impaired responsiveness to exteroceptive stimuliA Mikulecká
Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, CZ 142 20 4, Prague, Czech Republic
Behav Brain Res 117:29-39. 2000..We suggest that the model can be used for the study of both functional and morphological consequences of prolonged nonconvulsive seizures...
The diffusion parameters of the extracellular space are altered in focal cortical dysplasiasL Vargova
Department of Neuroscience and Center for Cell Therapy and Tissue Repair, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
Neurosci Lett 499:19-23. 2011....
Densities of parvalbumin-immunoreactive neurons in non-malformed hippocampal sclerosis-temporal neocortex and in cortical dysplasiasJ Zamecnik
Department of Pathology and Molecular Medicine, Charles University, 2nd Medical Faculty, V Uvalu 84, 150 06 Prague, Czech Republic
Brain Res Bull 68:474-81. 2006....
Clinical characteristics in patients with hippocampal sclerosis with or without cortical dysplasiaPetr Marusic
Neurology Department, Charles University, 2nd Faculty of Medicine, Motol Hospital, Praha, Czech Republic
Epileptic Disord 9:S75-82. 2007..The aim of the study was to review clinical variables of MTLE/HS patients in order to distinguish preoperatively patients with associated microscopic cortical dysplasia in the temporal pole...
Long-term behavioral and morphological consequences of nonconvulsive status epilepticus in ratsPavel Krsek
Institute of Physiology, Academy of Sciences of the Czech Republic, , CZ 142 20 Prague 4, Czech Republic
Epilepsy Behav 5:180-91. 2004..Despite relatively inconspicuous manifestations, NCSE may represent a risk for long-term deficits...
Nonlinear analysis of the sleep EEG in children with pervasive developmental disorderRobert Kulisek
Department of Child Psychiatry, Charles University, 2nd Faculty of Medicine, Prague, Czech Republic
Neuro Endocrinol Lett 29:512-7. 2008..We expected a lower degree of synchronization in autistic subjects...
Successful treatment of Ohtahara syndrome with chloral hydratePavel Krsek
Department of Pediatric Neurology, Charles University, Second Medical School, Prague, Czech Republic
Pediatr Neurol 27:388-91. 2002..We conclude that chloral hydrate could be useful in the treatment of severe epileptic encephalopathies. Possible indications of the drug for intractable epilepsy treatment are discussed...
(1)H MR spectroscopic imaging in patients with MRI-negative extratemporal epilepsy: correlation with ictal onset zone and histopathologyPavel Krsek
Department of Pediatric Neurology, Second Medical School, Motol Hospital, Charles University, Prague, Czech Republic
Eur Radiol 17:2126-35. 2007..1)H MRS could be more sensitive for the detection of discrete malformations of cortical development than conventional MRI. It is valuable in the presurgical evaluation of patients without MRI-apparent lesions...
