Vera Bubenikova

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. ncbi Models of schizophrenia in humans and animals based on inhibition of NMDA receptors
    Vera Bubenikova-Valesova
    Prague Psychiatric Center, Prague, Czech Republic
    Neurosci Biobehav Rev 32:1014-23. 2008
  2. ncbi The effect of tryptophan depletion on the action of haloperidol in MK-801-treated rats
    Vera Bubenikova
    Prague Psychiatric Center and Center of Neuropsychiatric Studies, 181 03 Prague 8, Czech Republic
    Eur J Pharmacol 502:109-16. 2004
  3. ncbi Effect of tandospirone, a serotonin-1A receptor partial agonist, on information processing and locomotion in dizocilpine-treated rats
    Vera Bubenikova-Valesova
    Department of Brain Pathophysiology and Biochemistry, Prague Psychiatric Centre, Prague, Czech Republic
    Psychopharmacology (Berl) 212:267-76. 2010
  4. ncbi Relation of sex and estrous phase to deficits in prepulse inhibition of the startle response induced by ecstasy (MDMA)
    V Bubenikova
    Prague Psychiatric Center, Prague, Czech Republic
    Behav Pharmacol 16:127-30. 2005
  5. ncbi The effect of zotepine, risperidone, clozapine and olanzapine on MK-801-disrupted sensorimotor gating
    Vera Bubenikova
    Prague Psychiatric Center affiliated with the Charles University 3rd Faculty of Medicine and the Center of Neuropsychiatric Studies, 181 03 Prague 8, Czech Republic
    Pharmacol Biochem Behav 80:591-6. 2005
  6. ncbi Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring
    Vera Bubenikova-Valesova
    Prague Psychiatric Center, Department of Biochemistry and Brain Pathophysiology, Ustavni 91, 181 03 Prague 8, Bohnice, Czech Republic
    Int J Dev Neurosci 27:525-30. 2009
  7. ncbi The opposite effect of a low and a high dose of serotonin-1A agonist on behavior induced by MK-801
    Vera Bubenikova-Valesova
    Prague Psychiatric Center and the Center of Neuropsychiatric Studies, Prague, Czech Republic
    Neuropharmacology 52:1071-8. 2007
  8. ncbi The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats
    Vera Bubenikova-Valesova
    Department of Brain Pathophysiology and Biochemistry, Prague Psychiatric Centre, Prague, Czech Republic
    Int J Neuropsychopharmacol 12:873-83. 2009
  9. ncbi Sex differences in the effects of N,N-diethyllysergamide (LSD) on behavioural activity and prepulse inhibition
    Tomas Palenicek
    Prague Psychiatric Center, Ustavni 91, 181 03, Prague 8, Czech Republic
    Prog Neuropsychopharmacol Biol Psychiatry 34:588-96. 2010
  10. ncbi Electroencephalographic spectral and coherence analysis of ketamine in rats: correlation with behavioral effects and pharmacokinetics
    Tomas Palenicek
    Prague Psychiatric Center, Prague, Czech Republic
    Neuropsychobiology 63:202-18. 2011

Collaborators

Detail Information

Publications16

  1. ncbi Models of schizophrenia in humans and animals based on inhibition of NMDA receptors
    Vera Bubenikova-Valesova
    Prague Psychiatric Center, Prague, Czech Republic
    Neurosci Biobehav Rev 32:1014-23. 2008
    ....
  2. ncbi The effect of tryptophan depletion on the action of haloperidol in MK-801-treated rats
    Vera Bubenikova
    Prague Psychiatric Center and Center of Neuropsychiatric Studies, 181 03 Prague 8, Czech Republic
    Eur J Pharmacol 502:109-16. 2004
    ..The effect of the tryptophan-free mixture combined with the classical antipsychotic haloperidol in MK-801-treated rats indicates the possibly important role of the serotonergic system in the action of antipsychotics...
  3. ncbi Effect of tandospirone, a serotonin-1A receptor partial agonist, on information processing and locomotion in dizocilpine-treated rats
    Vera Bubenikova-Valesova
    Department of Brain Pathophysiology and Biochemistry, Prague Psychiatric Centre, Prague, Czech Republic
    Psychopharmacology (Berl) 212:267-76. 2010
    ..Augmentation therapy with serotonin-1A receptor (5-HT1A) partial agonists has been suggested to ameliorate psychotic symptoms in patients with schizophrenia...
  4. ncbi Relation of sex and estrous phase to deficits in prepulse inhibition of the startle response induced by ecstasy (MDMA)
    V Bubenikova
    Prague Psychiatric Center, Prague, Czech Republic
    Behav Pharmacol 16:127-30. 2005
    ..Our result showed that female rats in the proestrous and estrous phases were less sensitive to the disruption of PPI by MDMA...
  5. ncbi The effect of zotepine, risperidone, clozapine and olanzapine on MK-801-disrupted sensorimotor gating
    Vera Bubenikova
    Prague Psychiatric Center affiliated with the Charles University 3rd Faculty of Medicine and the Center of Neuropsychiatric Studies, 181 03 Prague 8, Czech Republic
    Pharmacol Biochem Behav 80:591-6. 2005
    ..5 and 5 mg/kg) without MK-801 treatment. In summary, the four "atypical" antipsychotics had different efficacies to restore the disrupted PPI by MK-801. Only clozapine and olanzapin restored the MK-801-induced deficits in PPI...
  6. ncbi Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring
    Vera Bubenikova-Valesova
    Prague Psychiatric Center, Department of Biochemistry and Brain Pathophysiology, Ustavni 91, 181 03 Prague 8, Bohnice, Czech Republic
    Int J Dev Neurosci 27:525-30. 2009
    ..In conclusion, rats exposed to methamphetamine in utero have shown changes in the mesolimbic dopaminergic system and were more sensitive to the administration of the acute dose of methamphetamine in adulthood...
  7. ncbi The opposite effect of a low and a high dose of serotonin-1A agonist on behavior induced by MK-801
    Vera Bubenikova-Valesova
    Prague Psychiatric Center and the Center of Neuropsychiatric Studies, Prague, Czech Republic
    Neuropharmacology 52:1071-8. 2007
    ..In addition, these findings could indicate that activation of the 5-HT(1A) autoreceptor could be effective as a treatment in schizophrenia, but full potent agonism of the receptor could worsen the psychotic symptoms...
  8. ncbi The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats
    Vera Bubenikova-Valesova
    Department of Brain Pathophysiology and Biochemistry, Prague Psychiatric Centre, Prague, Czech Republic
    Int J Neuropsychopharmacol 12:873-83. 2009
    ..Thus, based on our results, over-activation of D1Rs may exacerbate psychotic symptoms in patients with schizophrenia...
  9. ncbi Sex differences in the effects of N,N-diethyllysergamide (LSD) on behavioural activity and prepulse inhibition
    Tomas Palenicek
    Prague Psychiatric Center, Ustavni 91, 181 03, Prague 8, Czech Republic
    Prog Neuropsychopharmacol Biol Psychiatry 34:588-96. 2010
    ..On the contrary although LSD disrupted PPI in males and MD female rats, EP females were protected from this disruptive effect. Thus, EP females seem to have a lower sensitivity to LSD behavioural actions...
  10. ncbi Electroencephalographic spectral and coherence analysis of ketamine in rats: correlation with behavioral effects and pharmacokinetics
    Tomas Palenicek
    Prague Psychiatric Center, Prague, Czech Republic
    Neuropsychobiology 63:202-18. 2011
    ..Analyses of behavioral measurements--locomotion and sensorimotor gating--and the pharmacokinetics of ketamine and norketamine were also conducted...
  11. ncbi Effect of low-frequency rTMS on electromagnetic tomography (LORETA) and regional brain metabolism (PET) in schizophrenia patients with auditory hallucinations
    Jiri Horacek
    Prague Psychiatric Center, Prague, Czech Republic
    Neuropsychobiology 55:132-42. 2007
    ..A neuroimaging study elucidating the effect of rTMS in auditory hallucinations has yet to be published...
  12. ncbi Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia
    Jiri Horacek
    Prague Psychiatric Centre, Prague, Czech Republic
    CNS Drugs 20:389-409. 2006
    ..This mechanism may normalise glutamatergic dysfunction and structural abnormalities and affect the core pathophysiological substrates for schizophrenia...
  13. ncbi Increased sensitivity to the acute effects of MDMA ("ecstasy") in female rats
    T Palenicek
    Laboratory of Biochemistry and Pathophysiology of the Brain, Prague Psychiatric Centre, Ustavni 91, 181 03 Prague 8, Czech Republic
    Physiol Behav 86:546-53. 2005
    ..Increased sensitivity of females to the behavioral effects of MDMA can be explained by increased reactivity of serotonergic and dopaminergic systems...
  14. ncbi The effect of tryptophan depletion on brain activation measured by functional magnetic resonance imaging during the Stroop test in healthy subjects
    J Horacek
    Prague Psychiatric Centre, Ustavni 91, 18100 Prague 8, Czech Republic
    Physiol Res 54:235-44. 2005
    ..The present findings allow the postulate that serotonergic medial forebrain and cingulum bundle pathways play a role in the activity of cortical structures involved in Stroop test processing...
  15. ncbi Risperidone and ritanserin but not haloperidol block effect of dizocilpine on the active allothetic place avoidance task
    Vera Bubenikova-Valesova
    Department of Brain Pathophysiology and Biochemistry, Prague Psychiatric Center, 181 03 Prague 8, Czech Republic
    Proc Natl Acad Sci U S A 105:1061-6. 2008
    ..This finding is in accordance with the assumption that some antipsychotics are primarily effective against cognitive dysfunction in schizophrenia...
  16. ncbi Age- and sex-dependent laterality of rat hippocampal cholinergic system in relation to animal models of neurodevelopmental and neurodegenerative disorders
    Zdena Kristofikova
    Prague Psychiatric Centre, Prague, Czech Republic
    Neurochem Res 29:671-80. 2004
    ..The data demonstrate viral infection-mediated alterations in normal patterns of brain asymmetry and are discussed in relation to animal models of neurodevelopmental and neurodegenerative diseases...