Research Topics
| H KozakovaSummaryAffiliation: Academy of Sciences of the Czech Republic Country: Czech Republic Publications
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Detail Information
Publications
Vitamin A deficiency leads to severe functional disturbance of the intestinal epithelium enzymes associated with diarrhoea and increased bacterial translocation in gnotobiotic ratsHana Kozakova
Department of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Novy Hradek, Czech Republic
Microbes Infect 5:405-11. 2003..e. the colonization state, has a strong influence on triggering the severity of the functional disturbances of the intestinal epithelium, and adds to the clinical manifestations of vitamin A deficiency...- Susceptibility to nasal and oral tolerance induction to the major birch pollen allergen Bet v 1 is not dependent on the presence of the microfloraAndreas Repa
Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, A 1090 Vienna, Austria
Immunol Lett 117:50-6. 2008..Our findings may challenge the view that the commensal microflora is a key factor for breakdown of physiological tolerance and allergy development... - Gut microbiota and lipopolysaccharide content of the diet influence development of regulatory T cells: studies in germ-free miceTomas Hrncir
Department of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague and Novy Hradek, Czech Republic
BMC Immunol 9:65. 2008.... - Humoral and cellular immune responses in gluten-treated suckling or hand-fed ratsH Kozakova
Department of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Novy Hradek
Physiol Res 49:665-72. 2000..Apoptotic DNA fragmentation in MLN cells was higher in gliadin-treated rats than in albumin-treated ones, independently of the milk diet during the suckling period... - Bifidobacterium bifidum monoassociation of gnotobiotic mice: effect on enterocyte brush-border enzymesH Kozakova
Department of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, 549 22 Novy Hradek, Czechia
Folia Microbiol (Praha) 46:573-6. 2001..This effect of B. bifidum supplementation was less pronounced for alkaline phosphatase, sucrase, glucoamylase and dipeptidyl peptidase i.v. in immature gut of weaned mice than of 2-month-old ones... - Effect of bacterial monoassociation on brush-border enzyme activities in ex-germ-free piglets: comparison of commensal and pathogenic Escherichia coli strainsHana Kozakova
Institute of Microbiology, Department of Immunology and Gnotobiology, Academy of Sciences of the Czech Republic, 549 22 Novy Hradek, Czech Republic
Microbes Infect 8:2629-39. 2006..coli strains. In conclusion, germ-free piglets represent a valuable tool to study the consequences of colonization of the immature sterile gut with defined strains of bacteria... - Monocolonization with Bacteroides ovatus protects immunodeficient SCID mice from mortality in chronic intestinal inflammation caused by long-lasting dextran sodium sulfate treatmentT Hudcovic
Department of Immunology, Academy of Sciences of the Czech Republic, Novy Hradek, Czech Republic
Physiol Res 58:101-10. 2009..This enzyme is known to reflect an imbalance between pro-oxidant and anti-oxidant mechanisms, which could be involved in protective effects of colonization of germ-free mice with Bacteroides ovatus against DSS injury... - Differential effect of Bacillus firmus on immune response and enterocyte brush-border enzyme levels in BALB/c and B10.BR miceH Kozakova
Department of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, 549 22 Novy Hradek, Czechia
Folia Microbiol (Praha) 47:759-65. 2002..The stimulation of immunoglobulin production after BF treatment was accompanied by changes in the levels of enterocyte brush-border enzymes; this responsiveness to BF treatment was genetically regulated... - Specific antibody and immunoglobulin responses after intestinal colonization of germ-free piglets with non-pathogenic Escherichia coli O86B Cukrowska
Division of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague
Immunobiology 204:425-33. 2001.... - Effects of monocolonization with Escherichia coli strains O6K13 and Nissle 1917 on the development of experimentally induced acute and chronic intestinal inflammation in germ-free immunocompetent and immunodeficient miceT Hudcovic
Department of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, 549 22 Novy Hradek, Czechia
Folia Microbiol (Praha) 52:618-26. 2007..coli Nissle 1917 exhibited only moderate inflammatory changes which were less pronounced than changes of colon mucosa of SCID mice monoassociated with E. coli O6K13... - Interaction of mucosal microbiota with the innate immune systemH Tlaskalova-Hogenova
Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
Scand J Immunol 62:106-13. 2005..As demonstrated in gnotobiotic animal models of human diseases, impaired regulation of mucosal responses to commensal bacteria plays an important role in the development of several inflammatory and autoimmune diseases... - Neonatal colonization of mice with Lactobacillus plantarum producing the aeroallergen Bet v 1 biases towards Th1 and T-regulatory responses upon systemic sensitizationM Schwarzer
Department of Immunology and Gnotobiology, Institute of Microbiology of the Academy of Sciences of the Czech Republic, v v i, Novy Hradek, Czech Republic
Allergy 66:368-75. 2011..Here, we investigated the effect of neonatal colonization with a recombinant LAB producing the major birch pollen allergen Bet v 1 in a murine model of type I allergy... - Cisplatin induced gamma-glutamyltransferase up-regulation, hypertrophy and differentiation in astrocytic glioma cells in cultureV Mares
Joint Laboratory of Cancer Cell Biology of the Institute of Physiology, Academy of Sciences, Charles University, Prague, Czech Republic
Histol Histopathol 18:687-93. 2003..The study showed that the transformed astrocytic cells can up-regulate GGT activity as part of an adaptation and/or, survival-enhancing reaction triggered by Cisplatin... - Colorectal carcinogenesis in germ-free and conventionally reared rats: different intestinal environments affect the systemic immunityLuca Vannucci
Laboratory of Natural Cell Immunity, Department of Immunology, Institute of Microbiology, Academy of Sciences of the Czech Republic, 14220 Prague 4, Czech Republic
Int J Oncol 32:609-17. 2008..The different levels of tolerance/regulatory mechanisms in GF versus the CV animals may modulate the anticancer response not only at the mucosal but also at the systemic immunity level... - Maternal milk reduces severity of necrotizing enterocolitis and increases intestinal IL-10 in a neonatal rat modelBohuslav Dvorak
Department of Pediatrics and Steele Memorial Children s Research Center, University of Arizona, Tucson, Arizona 85724, USA
Pediatr Res 53:426-33. 2003..Better understanding of the mechanisms underlying these protective effects could be beneficial either in the prevention of NEC or in the development of future therapeutic strategies to cure NEC...