Research Topics
| Jaroslava FolbergrováSummaryAffiliation: Academy of Sciences of the Czech Republic Country: Czech Republic Publications
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Detail Information
Publications
Brain superoxide anion formation in immature rats during seizures: protection by selected compoundsJaroslava Folbergrová
Institute of Physiology, Academy of Sciences of the Czech Republic, v v i, Videnska 1083, 142 20 Prague 4, Czech Republic
Exp Neurol 233:421-9. 2012....
Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acidJaroslava Folbergrová
Institute of Physiology, Academy of Sciences of the Czech Republic, vvi, Videnska 1083, 142 20 Prague 4, Czech Republic
Neurochem Int 56:394-403. 2010....
Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature ratsJaroslava Folbergrová
Institute of Physiology, v v i, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
Brain Res 1273:144-54. 2009..Neurol.192, 420-436, 2005)...
Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acidJaroslava Folbergrová
Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, Prague 4, Czech Republic
Neuropharmacology 54:665-75. 2008..The present findings suggest that receptor subtype 8 of group III mGluRs may be considered a promising target for drug therapy in childhood epilepsies in the future...
Mitochondrial complex I inhibition in cerebral cortex of immature rats following homocysteic acid-induced seizuresJaroslava Folbergrová
Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
Exp Neurol 204:597-609. 2007..We can assume that inhibition of complex I may elicit enhanced formation of reactive oxygen species and contribute thus to neuronal injury demonstrated in this model...
Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acidJaroslava Folbergrová
Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 14220 Prague 4, Czech Republic
Exp Neurol 201:105-19. 2006..Free radical scavenger PBN had a clear-cut protective effect, evident as the improved recovery of brain energy status and as a partial, but significant, attenuation of neuronal degeneration associated with this model of seizures...
Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylateJaroslava Folbergrová
Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
Exp Neurol 192:420-36. 2005..The present findings support the possibility that group II mGluRs are a promising target for a novel approach to treating epilepsy...
Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycineJaroslava Folbergrová
Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
Exp Neurol 180:46-54. 2003..The present findings suggest that group III mGlu receptor agonists may be of therapeutic significance for treating childhood epilepsies...
Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonistsJ Folbergrova
Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
Brain Res 908:120-9. 2001..Higher doses of (S)-4-C3HPG (1--100 nmol) were, however, less anticonvulsant than low doses. The present results have confirmed that mGluRs may be considered a potential target for treatment of epilepsy...
Neuronal cell death in hippocampus induced by homocysteic acid in immature ratsMilos Langmeier
Institute of Physiology, First Medical School, Charles University, Prague, Czech Republic
Epilepsia 44:299-304. 2003..To examine the morphologic alterations in the cerebral cortex and hippocampus of immature rats 6 days after the generalized clonic-tonic seizures induced by homocysteic acid (HCA)...
