Research Topics
| Lianet MonzoteSummaryAffiliation: Ciudad de La Habana Country: Cuba Publications
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Detail Information
Publications
Comparative chemical, cytotoxicity and antileishmanial properties of essential oils from Chenopodium ambrosioidesLianet Monzote
Institute of Medicine Tropical Pedro Kourí, Havana City, Cuba
Nat Prod Commun 6:281-6. 2011..ambrosioides but did change their cytotoxicity, which should be taken into account in further studies...- Activity of the essential oil from Chenopodium ambrosioides grown in Cuba against Leishmania amazonensisLianet Monzote
Parasitology Department, Institute of Tropical Medicine Pedro Kouri, Havana, Cuba
Chemotherapy 52:130-6. 2006..Current therapy against leishmaniasis is unsatisfactory. Efficacious and safe new drugs are needed. In this study, we show the leishmanicidal effect of an essential oil from Chenopodium ambrosioides against Leishmania amazonensis... - Mitochondria as a promising antiparasitic targetLianet Monzote
Departamento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Apartado Postal No 601, Marianao 13 Ciudad Habana, Cuba
Curr Clin Pharmacol 5:55-60. 2010..This review presents a compilation about the knowledge and understanding of the action of therapeutic agents on mitochondria from parasites and their future perspectives... - Chemistry, cytotoxicity and antileishmanial activity of the essential oil from Piper auritumLianet Monzote
Departamento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba
Mem Inst Oswaldo Cruz 105:168-73. 2010..The Piper-oil inhibited the growing of intracellular amastigotes of L. donovani with an IC50 value of 22.3 +/- 1.8 microg/mL. This study demonstrates the usefulness of the essential oils as a promising alternative to treat leishmaniasis... - Assessment of the knowledge of graphical symbols labelled on malaria rapid diagnostic tests in four international settingsVeerle Hermans
Department of Clinical Sciences, Institute of Tropical Medicine, Unit of Tropical Laboratory Medicine, Nationalestraat 155, B 2000 Antwerp, Belgium
Malar J 10:331. 2011..abstract:.. - Effect of thiadiazine derivatives on intracellular amastigotes of Leishmania amazonensisLianet Monzote Fidalgo
Departamento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba
Mem Inst Oswaldo Cruz 99:329-30. 2004..This activity suggests that thiadiazine derivatives could be considered as potential antileishmanial compounds... - Mitochondria and trypanosomatids: targets and drugsLianet Monzote Fidalgo
Departamento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Apartado Postal No 601, Marianao 13, Ciudad Habana, Cuba
Pharm Res 28:2758-70. 2011.... - Activity of Cuban propolis extracts on Leishmania amazonensis and Trichomonas vaginalisLianet Monzote Fidalgo
Parasitology Department, Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba
Nat Prod Commun 6:973-6. 2011..Cuban propolis extracts demonstrated activity against both intracellular and extracellular protozoa model, as well as the potentialities of propolis as a natural source to obtain new antiprotozoal agents... - Antileishmanial patents antileishmanial current drugs and relevant patentsLianet Monzote
Parasitology Department, Institute of Medicine Tropical Pedro Kourí, Havana City, Cuba
Recent Pat Antiinfect Drug Discov 6:1-26. 2011..Nevertheless, advances in the understanding of new metabolic pathways and drug targets in the parasite could offer new alternatives to treatment of leishmaniasis... - Effect of oral treatment with the essential oil from Chenopodium ambrosioides against cutaneous leishmaniasis in BALB/c mice, caused by Leishmania amazonensisLianet Monzote
Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba
Forsch Komplementmed 16:334-8. 2009..The aim of this study was to investigate the antileishmanial effect of Chenopodium oil administered by the oral route at different doses and to compare its action to conventional, clinically used drugs... - In vitro activity of an essential oil against Leishmania donovaniL Monzote
Departamento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba
Phytother Res 21:1055-8. 2007..The phagocytic activity of the macrophages was preserved at a concentration toxic to the parasite. The essential oil from C. ambrosioides may be a potential candidate drug to development a new agent to combat this parasitic disease... - A review of anti-parasitic patents (1988-2008)Lianet Monzote
Parasitology Department, Institute of Medicine Tropical Pedro Kourí, Havana City, Cuba
Recent Pat Antiinfect Drug Discov 3:177-91. 2008..The discovery of new antiparasitic drugs to obtain a solution to million of people who suffer and die due to parasitic diseases is an urgent need... - Combined effect of the essential oil from Chenopodium ambrosioides and antileishmanial drugs on promastigotes of Leishmania amazonensisLianet Monzote
Departamento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba
Rev Inst Med Trop Sao Paulo 49:257-60. 2007..However, an indifferent effect has been found for combinations of meglumine antimoniate or amphotericin B and the essential oil... - Activity, toxicity and analysis of resistance of essential oil from Chenopodium ambrosioides after intraperitoneal, oral and intralesional administration in BALB/c mice infected with Leishmania amazonensis: a preliminary studyLianet Monzote
Parasitology Department, Institute of Medicine Tropical Pedro Kourí, Apartado Postal No 601, Marianao 13, Havana City, Cuba
Biomed Pharmacother 61:148-53. 2007..amazonensis isolates obtained from treated mice. These data clearly demonstrated that this natural product could be an alternative for the development of a new drug against cutaneous leishmaniasis based in the ethnomedical information... - In vitro activities of thiadiazine derivatives against Leishmania amazonensisLianet Monzote
Departamento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Ciudad de la Habana Cuba
Arzneimittelforschung 55:232-8. 2005..However, the compounds exhibited high toxicity and provoked inhibition of the phagocytosis in the murine host cell... - Screening of medicinal plants against Leishmania amazonensisMarley García
Department of Parasitology, Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba
Pharm Biol 48:1053-8. 2010..Natural products are attractive due to their structural diversity... - Antileishmanial assessment of leaf extracts from Pluchea carolinensis, Pluchea odorata and Pluchea roseaMarley García
Parasitology Department, Institute of Medicine Tropical Pedro Kourí, Havana City, Cuba
Asian Pac J Trop Med 4:836-40. 2011..To evaluate the antileishmanial activity of different extracts from three Cuban Pluchea species... - Toxic effects of carvacrol, caryophyllene oxide, and ascaridole from essential oil of Chenopodium ambrosioides on mitochondriaLianet Monzote
Parasitology Department, Institute of Tropical Medicine Pedro Kouri, Apartado Postal No 601, Marianao 13, Havana City, Cuba
Toxicol Appl Pharmacol 240:337-47. 2009.... - Effect of Bixa orellana against Leishmania amazonensisMarley García
Departmento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba
Forsch Komplementmed 18:351-3. 2011..In the present study, an activity of Bixa orellana extract against Leishmania amazonensis was demonstrated... - Activity of Cuban Plants Extracts against Leishmania amazonensisMarley García
Department of Parasitology, Institute of Tropical Medicine Pedro Kouri, Apdo Postal No 601, Havana 10400, Cuba
ISRN Pharmacol 2012:104540. 2012..Furthermore, their toxicity was assayed against murine macrophage. The three most potent extracts against the amastigote stage of Leishmania amazonensis were from Hura crepitans, Bambusa vulgaris, and Simarouba glauca... - [PCR-RFLP and RAPD for typing neotropical Leishmania]Ana Margarita Montalvo
Departamento de Parasitologia, Instituto Pedro Kouri, La Habana, Cuba
Biomedica 28:597-606. 2008..The analysis of the PCR-restriction fragment length polymorphism and random amplified polymorphic DNA have been useful tools for Leishmania identification... - Antimalarial activity of new acridinone derivativesAymé Fernández-Calienes
Departamento de Parasitologia, Instituto de Medicina Tropical Pedro Kouri, Autopista Novia del Mediodía Km 6, Marianao 13, Ciudad de La Habana, Cuba
Biomed Pharmacother 65:210-4. 2011..2 ?g/mL with SI greater than 100. In molecular tests, no relevant inhibitory activity was obtained for our compounds. The mechanism of acridinones antimalarial action remains unclear...