Jorge Fernandez-de-Cossio

Summary

Affiliation: Center for Genetic Engineering and Biotechnology
Country: Cuba

Publications

  1. ncbi Isotopica: a tool for the calculation and viewing of complex isotopic envelopes
    Jorge Fernandez-de-Cossio
    Center for Genetic Engineering and Biotechnology, P O Box 6162, Havana, Cuba
    Nucleic Acids Res 32:W674-8. 2004
  2. ncbi Automated interpretation of mass spectra of complex mixtures by matching of isotope peak distributions
    Jorge Fernandez-de-Cossio
    Center for Genetic Engineering and Biotechnology, PO Box 6162, Havana, Cuba
    Rapid Commun Mass Spectrom 18:2465-72. 2004
  3. ncbi Mass spectrum patterns of 18O-tagged peptides labeled by enzyme-catalyzed oxygen exchange
    Jorge Fernandez-de-Cossio
    Bioinformatics Department, Center for Genetic Engineering and Biotechnology, P O Box 6162, CP 10600, C Habana, Cuba
    Anal Chem 83:2890-6. 2011
  4. ncbi Efficient packing Fourier-transform approach for ultrahigh resolution isotopic distribution calculations
    Jorge Fernandez-de-Cossio
    Bioinformatics Department, Center for Genetic Engineering and Biotechnology, P O Box 6162, CP 10600, C Habana, Cuba
    Anal Chem 82:1759-65. 2010
  5. ncbi Computation of the isotopic distribution in two dimensions
    Jorge Fernandez-de-Cossio
    Bioinformatics Department, Center for Genetic Engineering and Biotechnology, P O Box 6162, CP 10600, C Habana, Cuba
    Anal Chem 82:6726-9. 2010
  6. ncbi Proteomic profile regulated by the anticancer peptide CIGB-300 in non-small cell lung cancer (NSCLC) cells
    Arielis Rodríguez-Ulloa
    Department of Bioinformatics, Center for Genetic Engineering and Biotechnology, Havana, Cuba
    J Proteome Res 9:5473-83. 2010
  7. ncbi SCAPE: a new tool for the Selective CApture of PEptides in protein identification
    Lazaro Betancourt
    Department for Proteome Analysis, Center for Genetic Engineering and Biotechnology, P O Box 6162, Havana, Cuba
    J Proteome Res 4:491-6. 2005
  8. ncbi Introducing an Asp-Pro linker in the synthesis of random one-bead-one-compound hexapeptide libraries compatible with ESI-MS analysis
    Yordanka Masforrol
    Department of Chemical Synthesis, Division of Physical Chemistry, Center for Genetic Engineering and Biotechnology, Havana, Cuba
    ACS Comb Sci 14:145-9. 2012
  9. ncbi BisoGenet: a new tool for gene network building, visualization and analysis
    Alexander Martin
    Center for Genetic Engineering and Biotechnology, Havana, Cuba
    BMC Bioinformatics 11:91. 2010
  10. ncbi Proteomics based on peptide fractionation by SDS-free PAGE
    Yassel Ramos
    Center for Genetic Engineering and Biotechnology, La Habana, Cuba
    J Proteome Res 7:2427-34. 2008

Collaborators

Detail Information

Publications11

  1. ncbi Isotopica: a tool for the calculation and viewing of complex isotopic envelopes
    Jorge Fernandez-de-Cossio
    Center for Genetic Engineering and Biotechnology, P O Box 6162, Havana, Cuba
    Nucleic Acids Res 32:W674-8. 2004
    ..The web server can be accessed at http://bioinformatica.cigb.edu.cu/isotopica and http://coco.protein.osaka-u.ac.jp/isotopica [correction]...
  2. ncbi Automated interpretation of mass spectra of complex mixtures by matching of isotope peak distributions
    Jorge Fernandez-de-Cossio
    Center for Genetic Engineering and Biotechnology, PO Box 6162, Havana, Cuba
    Rapid Commun Mass Spectrom 18:2465-72. 2004
    ..It is particularly useful for resolving the relative abundances of narrow-split paired peaks caused by enrichment with a stable isotope, such as 18O, 13C, 2H, or 15N...
  3. ncbi Mass spectrum patterns of 18O-tagged peptides labeled by enzyme-catalyzed oxygen exchange
    Jorge Fernandez-de-Cossio
    Bioinformatics Department, Center for Genetic Engineering and Biotechnology, P O Box 6162, CP 10600, C Habana, Cuba
    Anal Chem 83:2890-6. 2011
    ..Accuracy and time dependency are examined and compared with actual labeled-digest data...
  4. ncbi Efficient packing Fourier-transform approach for ultrahigh resolution isotopic distribution calculations
    Jorge Fernandez-de-Cossio
    Bioinformatics Department, Center for Genetic Engineering and Biotechnology, P O Box 6162, CP 10600, C Habana, Cuba
    Anal Chem 82:1759-65. 2010
    ..This packing procedure reduced 8 to 32 times the computation resources in comparison to the same calculation performed without packing. The procedure can be readily implemented in existing software...
  5. ncbi Computation of the isotopic distribution in two dimensions
    Jorge Fernandez-de-Cossio
    Bioinformatics Department, Center for Genetic Engineering and Biotechnology, P O Box 6162, CP 10600, C Habana, Cuba
    Anal Chem 82:6726-9. 2010
    ..The superiority over well-established methods in terms of accuracy, speed, and memory resources is clearly demonstrated for high and ultrahigh resolution ranges by a program implementing the algorithm...
  6. ncbi Proteomic profile regulated by the anticancer peptide CIGB-300 in non-small cell lung cancer (NSCLC) cells
    Arielis Rodríguez-Ulloa
    Department of Bioinformatics, Center for Genetic Engineering and Biotechnology, Havana, Cuba
    J Proteome Res 9:5473-83. 2010
    ..The protein translation process was the most affected (23% of the identified proteins). From the proteome analysis of the NCI-H125 cell line, novel potentialities for CIGB-300 as anticancer agent were evidenced...
  7. ncbi SCAPE: a new tool for the Selective CApture of PEptides in protein identification
    Lazaro Betancourt
    Department for Proteome Analysis, Center for Genetic Engineering and Biotechnology, P O Box 6162, Havana, Cuba
    J Proteome Res 4:491-6. 2005
    ..The simplicity of the method and the results obtained in silico and with standard proteins, anticipate the utility of the SCAPE approach for proteome analyses...
  8. ncbi Introducing an Asp-Pro linker in the synthesis of random one-bead-one-compound hexapeptide libraries compatible with ESI-MS analysis
    Yordanka Masforrol
    Department of Chemical Synthesis, Division of Physical Chemistry, Center for Genetic Engineering and Biotechnology, Havana, Cuba
    ACS Comb Sci 14:145-9. 2012
    ..The proposed strategy is also compatible with stepwise Edman degradation using either intact beads or the released free peptides...
  9. ncbi BisoGenet: a new tool for gene network building, visualization and analysis
    Alexander Martin
    Center for Genetic Engineering and Biotechnology, Havana, Cuba
    BMC Bioinformatics 11:91. 2010
    ..The development of software tools capable of integrating data from different sources and to provide flexible methods to reconstruct, represent and analyze topological networks is an active field of research in bioinformatics...
  10. ncbi Proteomics based on peptide fractionation by SDS-free PAGE
    Yassel Ramos
    Center for Genetic Engineering and Biotechnology, La Habana, Cuba
    J Proteome Res 7:2427-34. 2008
    ..The analysis of a membrane protein extract from Neisseria meningitidis by this approach allowed the identification of 97 proteins, including low-abundance components...
  11. ncbi A methodology based on molecular interactions and pathways to find candidate genes associated to diseases: its application to schizophrenia and Alzheimer's disease
    Maria Elena Ochagavia
    Bioinformatics Department, Center for Genetic Engineering and Biotechnology, Ave 31 e 158 y 190 Havana, P O Box 6162, Cuba
    J Bioinform Comput Biol 9:541-57. 2011
    ..In both cases, we were able to predict a statistically significant amount of genes belonging to the updated lists...