Zhe Yu

Summary

Country: China

Publications

  1. ncbi Therapeutic potential of irreversible electroporation in sarcoma
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi, 710038, PR China
    Expert Rev Anticancer Ther 12:177-84. 2012
  2. ncbi Activation of antitumor cytotoxic T lymphocytes by fusion of patient-derived dendritic cells with autologous osteosarcoma
    Z Yu
    Center of Orthopedic Surgery Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, Shaanxi, China
    Exp Oncol 27:273-8. 2005
  3. ncbi Therapeutic potential of dendritic cell vaccines in sarcoma of the extremities
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi, P R China
    Expert Rev Anticancer Ther 9:1065-71. 2009
  4. ncbi Specific antitumor effects of tumor vaccine produced by autologous dendritic cells transfected with allogeneic osteosarcoma total RNA through electroporation in rats
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi China
    Cancer Biol Ther 8:973-80. 2009
  5. ncbi Allogeneic tumor vaccine produced by electrofusion between osteosarcoma cell line and dendritic cells in the induction of antitumor immunity
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLSA, Shaanxi, China
    Cancer Invest 25:535-41. 2007
  6. ncbi Establishment of reproducible osteosarcoma rat model using orthotopic implantation technique
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Shaanxi 710038, PR China
    Oncol Rep 21:1175-80. 2009
  7. ncbi Specific antitumor effects of tumor vaccine produced by electrofusion between osteosarcoma cell and dendritic cell in rats
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, Shanxi, China
    Cell Mol Immunol 1:454-60. 2004
  8. ncbi [Inducing specific antitumor effects on osteosarcoma by fused vaccine of rat dendritic cells]
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, The Fourth Military Medical University, Xi an, Shaanxi, 710038, P R China
    Ai Zheng 24:285-91. 2005
  9. ncbi Establishment and characterization of human osteosarcoma cell lines with different pulmonary metastatic potentials
    Xiang Chen
    Department of Orthopaedic Surgery, Tangdu Hospital, The Fourth Military Medical University, 710038, Xi an, China
    Cytotechnology 61:37-44. 2009
  10. ncbi Functional and radiological evaluations of unstable displaced proximal humeral fractures treated with closed reduction and percutaneous pinning fixation
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, PR China yuzhe780519 yahoo com cn
    Eur Surg Res 45:138-45. 2010

Collaborators

Detail Information

Publications26

  1. ncbi Therapeutic potential of irreversible electroporation in sarcoma
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi, 710038, PR China
    Expert Rev Anticancer Ther 12:177-84. 2012
    ..In this article, a series of recently conducted irreversible electroporation treatment for sarcomas based on local nonthermal ablation are summarized, and the therapeutic potential of this newly developed technique is assessed...
  2. ncbi Activation of antitumor cytotoxic T lymphocytes by fusion of patient-derived dendritic cells with autologous osteosarcoma
    Z Yu
    Center of Orthopedic Surgery Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, Shaanxi, China
    Exp Oncol 27:273-8. 2005
    ..This study was designed to investigate the antitumor effects of tumor vaccine produced by electrofusion between human osteosarcoma cells and DCs...
  3. ncbi Therapeutic potential of dendritic cell vaccines in sarcoma of the extremities
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi, P R China
    Expert Rev Anticancer Ther 9:1065-71. 2009
    ..In this review, a series of recently conducted immunotherapy for extremital sarcomas based on DCs are summarized and the potential for therapeutic DC vaccination targeted against these tumors is assessed...
  4. ncbi Specific antitumor effects of tumor vaccine produced by autologous dendritic cells transfected with allogeneic osteosarcoma total RNA through electroporation in rats
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi China
    Cancer Biol Ther 8:973-80. 2009
    ..This study was designed to investigate the antitumor effects of tumor vaccine produced by autologous dendritic cells transfected with allogeneic osteosarcoma total RNA through electroporation in tumor-bearing rats model...
  5. ncbi Allogeneic tumor vaccine produced by electrofusion between osteosarcoma cell line and dendritic cells in the induction of antitumor immunity
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLSA, Shaanxi, China
    Cancer Invest 25:535-41. 2007
    ..This study was designed to investigate the antitumor effects of tumor vaccine produced by electrofusion between rat osteosarcoma cells and allogeneic DCs...
  6. ncbi Establishment of reproducible osteosarcoma rat model using orthotopic implantation technique
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Shaanxi 710038, PR China
    Oncol Rep 21:1175-80. 2009
    ..Ultrasound was found to be a highly accurate tool for tumor diagnosis, localization and measurement and may be recommended for monitoring tumor growth in this model...
  7. ncbi Specific antitumor effects of tumor vaccine produced by electrofusion between osteosarcoma cell and dendritic cell in rats
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, Shanxi, China
    Cell Mol Immunol 1:454-60. 2004
    ....
  8. ncbi [Inducing specific antitumor effects on osteosarcoma by fused vaccine of rat dendritic cells]
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, The Fourth Military Medical University, Xi an, Shaanxi, 710038, P R China
    Ai Zheng 24:285-91. 2005
    ..But immune therapy based on DCs for osteosarcoma has seldom been reported. This study was designed to investigate the immunologic potency and antitumor effects of fused vaccine of rat DCs on osteosarcoma...
  9. ncbi Establishment and characterization of human osteosarcoma cell lines with different pulmonary metastatic potentials
    Xiang Chen
    Department of Orthopaedic Surgery, Tangdu Hospital, The Fourth Military Medical University, 710038, Xi an, China
    Cytotechnology 61:37-44. 2009
    ..Hence, these well-characterized human OSA sublines can be used as valuable models for comparative studies of genetic determinants of OSA in the future...
  10. ncbi Functional and radiological evaluations of unstable displaced proximal humeral fractures treated with closed reduction and percutaneous pinning fixation
    Zhe Yu
    Center of Orthopedic Surgery, Orthopedics Oncology Institute of Chinese PLA, Tangdu Hospital, Fourth Military Medical University, Xi an, PR China yuzhe780519 yahoo com cn
    Eur Surg Res 45:138-45. 2010
    ..The purpose of this study is to evaluate the functional and radiological outcomes of patients with unstable displaced proximal humeral fractures treated with closed reduction and percutaneous pinning (CRPP) fixation...
  11. ncbi Prognostic significance of p16 protein levels in oropharyngeal squamous cell cancer
    Paul M Weinberger
    Department of Medical Oncology, Yale University School of Medicine, New Haven, Connecticut, USA
    Clin Cancer Res 10:5684-91. 2004
    ..CONCLUSIONS: In patients with oropharyngeal squamous cell carcinoma, overexpression of p16 as determined by immunohistochemistry is associated with significantly improved prognosis and lower local recurrence rates...
  12. ncbi Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study
    P Dong
    Department of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University, Affiliated Shanghai First People s Hospital, China
    J Laryngol Otol 121:1177-83. 2007
    ..To determine the correlation between expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2, in patients with laryngeal carcinoma...
  13. ncbi Dihydropyrimidine dehydrogenase activity correlates with fluorouracil sensitivity in breast cancer
    Z Yu
    Department of Breast Surgery, the Second Affiliated Hospital of Shandong University, Ji Nan, Shandong Province, People s Republic of China
    Exp Oncol 29:192-6. 2007
    ..The identification of biological factors associated with tumors either responsiveness or resistance to FU chemotherapy, including FU, is increasingly being recognized as an important field of clinical cancer research...
  14. ncbi Regulatory network motifs and hotspots of cancer genes in a mammalian cellular signalling network
    A Awan
    Biotechnology Research Institute, National Research Council Canada, Montreal, Quebec, Canada H4P 2R2
    IET Syst Biol 1:292-7. 2007
    ..These results have implications for the foundations of the regulatory mechanisms of cancer development and metastasis...
  15. ncbi Calcium depletion enhances nectin-1 expression and herpes oncolytic therapy of squamous cell carcinoma
    Z Yu
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Gene Ther 14:738-47. 2007
    ..This strategy might have future application toward improving therapy with a variety of herpes vectors...
  16. ncbi Inverted duplication pattern in anaphase bridges confirms the breakage-fusion-bridge (BFB) cycle model for 11q13 amplification
    S C Reshmi
    Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Cytogenet Genome Res 116:46-52. 2007
    ....
  17. ncbi The neurotoxic prion peptide fragment PrP(106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1
    Y Le
    Laboratory of Molecular Immunoregulation, Division of Basic Sciences, National Cancer Institute-Frederick, Science Applications International Corporation-Frederick, Frederick, MD 21702, USA
    J Immunol 166:1448-51. 2001
    ..Thus, FPRL1 may act as a "pattern recognition" receptor that interacts with multiple pathologic agents and may be involved in the proinflammatory process of prion diseases...
  18. ncbi CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity
    Z Yu
    Department of Immunology, Mayo Clinic, Rochester, MN 55905, USA
    Ann Neurol 49:146-54. 2001
    ..Half of those remaining had miscellaneous neoplasms; all but two were smokers. Serum IgG in all cases bound to recombinant CRMP-5 (predominantly N-terminal epitopes), but not to human CRMP-2 or CRMP-3...
  19. ncbi Paraneoplastic optic neuropathy and cerebellar ataxia with small cell carcinoma of the lung
    M R Thambisetty
    Departments of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA
    J Neuroophthalmol 21:164-7. 2001
    ..Unexplained optic neuropathy in the setting of subacute cerebellar ataxia should cause suspicion of a paraneoplastic disorder and prompt testing for this autoantibody, especially in patients at risk for lung carcinoma...
  20. ncbi [Clinico-pathologic study on extended radical resection for rectal cancer]
    X Dong
    Department of Abdominal Surgery, Harbin Medical University Third Hospital, Harbin 150040, China
    Zhonghua Zhong Liu Za Zhi 23:323-5. 2001
    ....
  21. ncbi A phase 1 study of tazarotene in adults with advanced cancer
    P H Jones
    MRC Cancer Cell Unit and Cancer Research UK Department of Oncology, University of Cambridge, Hutchison MRC Research Centre, Cambridge CB2 2XZ, UK
    Br J Cancer 89:808-15. 2003
    ..2 or 33.4 mg day(-1)). We conclude that oral tazarotene is well tolerated when administered daily for 12 weeks, has a favourable toxicity profile compared with other retinoids and merits further investigation as an anticancer therapy...
  22. ncbi Thymidylate synthase predicts for clinical outcome in invasive breast cancer
    Z Yu
    Department of Surgery, the Second Affiliated Hospital of Shandong University, Ji Nan, Shandong Province, People s Republic of China
    Histol Histopathol 20:871-8. 2005
    ..TS expression in the primary tumor might be useful as a predictive parameter for the efficacy of 5-FU-based chemotherapy for breast cancer...
  23. ncbi Enhanced immunogenicity and antitumour effects with heterologous prime-boost regime using vaccines based on MG7-Ag mimotope of gastric cancer
    T Lin
    State Key Laboratory of Cancer Biology, Institute of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, 15 Changle West Road, Xi'an 710032, China
    Clin Exp Immunol 144:319-25. 2006
    ....
  24. ncbi Automated quantitative analysis of DCC tumor suppressor protein in ovarian cancer tissue microarray shows association with beta-catenin levels and outcome in patients with epithelial ovarian cancer
    A Bamias
    Department of Clinical Therapeutics, University of Athens, School of Medicine, Athens, Greece
    Ann Oncol 17:1797-802. 2006
    ..Here, we sought to determine the association of DCC with beta-catenin protein levels, clinicopathological parameters and patient outcome in ovarian cancer using a method of in situ compartmentalized protein analysis...
  25. ncbi Analysis of p53 protein expression levels on ovarian cancer tissue microarray using automated quantitative analysis elucidates prognostic patient subsets
    A Psyrri
    Department of Medical Oncology, Yale Cancer Center, New Haven, CT 06520, USA diamando psyrri yale edu
    Ann Oncol 18:709-15. 2007
    ..Here, we sought to determine the prognostic value of p53 in ovarian cancer using a novel method of compartmentalized in situ protein analysis...
  26. ncbi HCPTPA, a protein tyrosine phosphatase that regulates vascular endothelial growth factor receptor-mediated signal transduction and biological activity
    L Huang
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Biol Chem 274:38183-8. 1999
    ..Potential interactions with other signaling pathways and possible therapeutic implications are discussed...