O S Tang

..Although the initial MRI picture may be misleading, the diagnosis of thrombosis should always be kept in mind, as it is the commonest cause of intracranial lesions after OHSS...

..A combination of mifepristone and misoprostol provides an effective method of medical abortion for early pregnancy. A new route of administration of misoprostol, the sublingual route, was investigated in this study...

..Prolonged vaginal bleeding is a common complaint after medical abortion. The effect of a 1 week course of daily oral misoprostol after medical abortion with mifepristone and misoprostol on the amount of post-abortal blood loss was studied...

..A randomized controlled trial comparing sublingual with vaginal administration of misoprostol for medical management of silent miscarriages...

..Other applications including treatment for fibroids, endometriosis and various cancers have been explored. However, its association with abortion limits the applications of mifepristone in many of these areas...

..This is the first randomized trial comparing the use of sublingual misoprostol with vaginal misoprostol in combination with mifepristone for termination of early pregnancies up to 63 days...

..This study aimed to compare a new route of sublingual administration to the vaginal route of administration for pre-operative cervical priming in first trimester surgical abortion...

..This paper reviews the current management of early pregnancy failure with particular emphasis on the use of misoprostol...

..Further studies are required to determine the optimal dose and route of administration of misoprostol that can give the highest complete abortion rate, lowest ongoing pregnancy rate and least side effects...

..A prospective double-blinded placebo-controlled trial was done to compare the efficacy and side-effects of sublingual to oral misoprostol when used with mifepristone for medical abortion from 12 to 20 weeks gestation...

..These studies can help to discover the optimal dose and route of administration of misoprostol for individual clinical applications. Misoprostol is a safe drug but serious complications and teratogenicity can occur with unsupervised use...

..A sublingual misoprostol-alone regimen was used in 50 women requesting medical abortion at up to 12 weeks gestation. The efficacy and acceptability of this regimen were studied...

..This randomized controlled trial compared the use of sublingual misoprostol with or without an additional 1 week course of sublingual misoprostol for the medical management of silent miscarriage...

..The pharmacokinetic parameters of four different routes of administration of a single dose of 400 microg of misoprostol were studied...

..Prospective randomized studies are required to compare its efficacy and side effects with vaginal misoprostol and to work out the dosage and dosing interval...

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..Recent reports suggested that ultrasound guidance during embryo transfer might improve the pregnancy rate...

..6) and 14.0 (2.5th-97.5th centiles: 0-99.1). These pain levels during egg collection were not significantly different between the two groups. The use of 200 mg lignocaine in PCB is not justified, even in the absence of toxic effects...

..We compared sodium nitroprusside gel to misoprostol, the standard agent for cervical priming in this randomized double-blinded controlled trial...

..The objective of this randomized comparison study is to compare two intervals of administration of misoprostol after pretreatment with mifepristone for second trimester medical abortion...

..To compare the pain levels during egg collection and the subsequent postoperative side effects in patients receiving a paracervical block (PCB) with and without conscious sedation...

..This is the first randomized study to compare vaginal misoprostol versus expectant treatment in women presenting with spontaneous miscarriage...

..Common side effects of misoprostol-induced termination of pregnancy include gastrointestinal side effects, abdominal cramps, bleeding, fever and chills. Complications may include infection or rarely rupture of uterus...

..To compare endometrial and subendometrial blood flows among patients with and without hydrosalpinx (HSP) during in vitro fertilization treatment as measured by a three-dimensional power Doppler ultrasound...

..To compare sublingual misoprostol with intravenous syntometrine use during third stage of labor by measuring the blood loss...

..We compared the ultrasonographic parameters for endometrial receptivity between 2 consecutive in vitro fertilization (IVF) cycles in the same patients...

..The aim of this prospective study was to compare antral follicle count (AFC), ovarian volume and ovarian stromal blood flow measured by three-dimensional (3D) power Doppler ultrasound before and after pituitary downregulation...

..No differences in efficacy were observed when amenorrhoea length was < 57 days...

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..Vaginal misoprostol should be the regimen of choice but sublingual misoprostol is also an effective alternative...

..No information exists in the literature regarding the factors affecting the blood flow towards the endometrial and subendometrial regions during IVF treatment...

..Endometrial and subendometrial blood flow were compared between excessive responders (serum E(2) on the day of HCG >20 000 pmol/l) and moderate responders (E(2) < or =20 000 pmol/l)...

..Low implantation rates in stimulated IVF cycles may be related to suboptimal endometrial perfusion. Endometrial and subendometrial blood flow was compared between stimulated and natural cycles in the same patients undergoing IVF...

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..Pain related to the abortion process occurs earlier after oral misoprostol. Should a need arise, a majority of women would choose medical abortion again and would prefer to have it at a health facility rather than at home...

..To report the results of in vitro fertilization and embryo transfer (IVF/ET) performed during natural cycles...

..Different doses of human chorionic gonadotropin (hCG) have been used in various in vitro fertilization (IVF) treatment protocols to achieve final oocyte maturation. There is as yet no agreement on the optimum dose required...

..There were no differences in all the indices of endometrial, subendometrial, and ovarian stromal blood flow in women who had received 250 microg or 500 microg of recombinant hCG for final oocyte maturation...

..There was a trend for the study group to have higher ovarian stromal blood flow...

..To study the effects of green tea on body weight, and biochemical and hormonal profiles in obese Chinese women with polycystic ovary syndrome (PCOS)...

..The bioavailability of a drug is affected by its route of administration. Herein, the bioavailability of hCG was compared after intramuscular (i.m.) or subcutaneous (s.c.) injection in obese and non-obese women...

..We compared endometrial and subendometrial blood flow between women with and without intramural fibroids during IVF treatment...

..To compare the biochemical markers of bone turnover in hypoestrogenic women who had been on the standard dosage of Premarin 0.625 mg to that of the age-matched women who were menstruating spontaneously...

..In addition, misoprostol can also be used as a cervical priming agent prior to dilatation and evacuation in second-trimester abortion...

..To investigate changes in the uterine artery and ovarian stromal blood flow in relation to the time of the day after pituitary down-regulation during in vitro fertilization treatment...

..This study was conducted to assess the efficacy and incidence of side effects of a regimen of repeated doses of 400 microg sublingual misoprostol for termination of pregnancy of <7 weeks gestation...

..The current study compared the efficacy of 3D-HyCoSy with diagnostic laparoscopy and its feasibility as a screening test for tubal patency...

..The discriminative capacity of CAT in the diagnosis of tubal pathology including both proximal and distal obstruction was not improved by measuring serum CA-125, regardless of the threshold values of serum CA-125 concentration...

..These regimens are still effective with an abortion rate of >90% in 48 hours. However, the induction to abortion interval (15 hours) is much longer. Intra-cervical tents can be used to shorten the induction to abortion intervals...

..To aid the design of effective and safe regimens, we have investigated the pharmacokinetic parameters after the vaginal or sublingual administration of repeated doses of 400 microg of misoprostol...

..To compare ovarian stromal blood flow indices in the follicular phase and after clomiphene citrate (CC) in infertile women...

..We aimed to evaluate the role of endometrial and subendometrial blood flows in the prediction of pregnancy during IVF treatment...

..Blood flow towards the peri-implantation endometrium may have effects on miscarriage and live birth following assisted reproduction treatment, in addition to its role in implantation...

..A good blood supply to the endometrium is usually considered as an essential requirement for implantation...

..Ovarian 3D power Doppler flow indices measured after pituitary down-regulation were not predictive of the ovarian response and pregnancy in the IVF treatment...

..Patients were aged <40 years with basal FSH <10 IU/l on recruitment for IVF treatment...

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..Mifepristone has been used for a number of other indications, but further studies are needed before such treatment can be recommended...

..To compare the implantation and ongoing pregnancy rates of frozen-thawed embryo transfer (FET) using laser thinning with those of laser breaching of the zona pellucida (ZP)...

..Little information exists in the literature regarding the role of AH in frozen-thawed embryo transfer (FET) cycles...