W W Lu

..An in vitro biomechanical study on lumbar intervertebral joints...

..Fifty-five human thoracolumbar vertebrae were randomly fatigue loaded and analyzed...

..An in vitro biomechanical and radiographic study to evaluate the properties of a newly developed bioactive bone cement for stabilization of the fractured spine, suitable for minimally invasive application...

..Unbalanced electromyographic patterns found in patients with LBP given symmetrical tasks were not affected by rehabilitation treatment...

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..We conclude that calcium cross-linked alginate microbeads can act as a scaffold for BMC proliferation and osteogenic differentiation and has potential for use as 3D degradable scaffold...

..Compared with coatings, the plasma-implanted structure does not delaminate as easily and nitrogen PIII is a viable way to improve the properties of NiTi orthopedic implants...

..Combination of low stiffness and high mechanical strength gives the novel bone cement the potential for use in vertebroplasty cement applications...

..5% may not change chemical composition and lattice structure of bone, while it will broaden the bone crystal size distribution and strengthen the bone...

..In addition, our in vitro tests show that the plasma-treated surfaces are well tolerated by osteoblasts. Among the three types of samples, the best biological effects are observed on the nitrogen PIII samples...

..This method not only improves the overall mechanical performance but also increases osteoblastic activity...

..This young bone then becomes mature bone, which bonds tightly to the Sr-HA cement with collagen fibers inserted perpendicularly after 6 months...

..The strength of fixation seems to have a negative correlation with aging...

..Differences in morphology and chemical component between these two interfaces provided convincing evidences for the proposed dissolution-precipitation coupling mechanism in the formation of biological apatite...

..We conclude that alginate microcapsules can act as three-dimensional matrix for ATSC proliferation and has potential for use as injectable, biodegradable scaffold in bone tissue engineering...

..25% (p <.05) and 46.91% (p <.05) in comparison with the fractured spines. Results from this study revealed that the MMA-treated SrHAC has a better mechanical effect for orthopedic applications...

..These findings indicate that Sr alginate represent a significant improvement over Ca- and Ba alginate microbeads for the maintenance of chondrogenic phenotype of primary chondrocytes and IVD cells...

..To verify the applicability and validity of time-frequency analysis (TFA) of evoked potential (EP) signals in detecting the integrity of spinal cord function and preventing spinal cord injury...

..The remarkable simplicity of this process makes it widely accessible as an enabling technique for applications from engineering materials treatment including energy-absorption materials and pollution-treatment materials to biotechnology...

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..Radiopacity of SrHAC allowed easy radiographic imaging. The use of SrHAC cement is, thus, promising in spinal surgery...

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..Results suggested good bioactivity and bone-bonding ability of the Sr-HA cement under weight-bearing conditions...

..Sr-HA bone cement loaded with gentamicin was proven to be an efficient drug delivery system with uncompromised mechanical properties and bioactivity...

..The mechanical properties indicated that these two interfaces were diffused interfaces, and cancellous bone or cortical bone was grown into Sr-HA cement 6 months after the implantation...

..Results show that the Sr-HA cement is biocompatible and osteoconductive, which is suitable for use in treating osteoporotic vertebral fractures...

..Strontium-substituted HAp might be usable as a template for the growth of new bone, since nucleation appears to be facilitated...

..Strontium, in the form of strontium-containing hydroxyapatite (Sr-HA), was confirmed to enhance bioactivity in the PEEK composites...

..Stimulus rates in the range of 21 to 61 Hz are equivalent for quick and reliable detection of SCEP. Considering the short latency of SCEP, a pulse duration of 0.2 ms is recommended for SCEP using epidural stimulation...

..3%+/-6.2%) than ADS (41.8%+/-19.6%). Application of the CSD algorithm showed both good resolution and accurate spectrograms, and is therefore recommended as the most appropriate TFA technique for the analysis of SSEP signals...

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..These results help to elucidate the different nickel release behavior and bioactivity of porous NiTi alloys processed by different methods...

..Use of bioactive bone cement may be a possible solution overcoming problems associated with the use of PMMA bone cement in revision hip replacement...

..The creep properties of the samples are also characterized by a novel procedure using nanoindentation. The measured mechanical properties correlate well with the calcium content of the bone samples...

..Deconvolution of the stress and strain during loading is a simple and practical method for the recovery of higher frequency data from stress-relaxation experiments...

..Experimental animal study...

..CONCLUSIONS: The results demonstrate that multilevel fenestrations and discectomies affect lumbar spinal stability in flexion, but have no effect on the stability of the lumbar spine in lateral bending or axial rotation...

..The novel MSCs-seeded, PGA-HA biphasic graft facilitated both articular cartilage and subchondral bone regeneration in an animal model and might serve as a new approach for clinical applications...

..Optimal sacral screw insertion pathways were also outlined based on bone mineral density values...

..A pulse duration of 0.3 ms is recommended for SEP using posterior tibial nerve stimulation...

..This overall stiffness of the chest cage and the spine may contribute to the mechanical inefficiency and impairment of pulmonary function found in scoliotic patients...

..The reduced MF seen when wearing AFOs suggested an improvement of walking endurance. The DAFO had the advantage of less restriction on ankle movement, which avoids muscular atrophy and improves orthotic compliance...

..Lateral plating with six screws seems to provide the most rigid fixation. If such lateral plating is not practicable, the four-Kirschner wire method would be a satisfactory alternative...

..Based on XRD analysis crystallinity of HA approached 98%. Therefore, high temperature treatment improved long term stability of the coating through improved crystallinity of hydroxyapatite and reduced other impure calcium phosphate phase...

..The gender and body weight had a significant positive correlation to lifting capacity while job physical demand had a moderate correlation. Age and body heights were weakly correlated to lifting capacity...

..The results show that, under 100N axial load, the palmar locking compression T-plate restores stability comparable to that of the intact radius, and is superior to conventional palmar or dorsal T-plates...

..The purpose of this investigation was to employ new technological developments to determine the relation between spinal muscle contraction and spinal stiffness over a large region of the lumbar spine...

..Experimental study evaluated electrophysiological and histologic changes in the paraspinal muscle after spinal fusion...

..To investigate the improvement in the reliability of intraoperative spinal cord monitoring by applying time-frequency analysis to somatosensory evoked potentials (SEP)...

..This study is, to our knowledge, the first to establish the feasibility of AAV-based BMP2 gene therapy for endochondral ossification in immunocompetent animals...

..Dynamic lumbar flexion-extension motions were assessed by an electrogoniometer and a videofluoroscopy unit simultaneously...

..Because of its fast and reliable SEP detection, the ASE method is ideal for spinal cord monitoring in the clinical setting...

..Among the two types of samples, the best biological effects are found on the samples with nitrogen implantation...

..The paraspinal muscles in the thoracic region showed lower activity after spine fusion, probably because of atrophy. Higher muscular activity was found in the lumbar region, which may lead to muscle hypertrophy...

..Evaluation of a novel, leakage-free vertebroplastic instrumentation by fresh cadaveric studies...

..Intersubject muscle activity patterns varied...

..This implant coupling has the potential to be used as a very low profile system and also in nonfusion technologies in which demands on the coupling would not higher without the protection of spinal fusion...

..The insertion torque and pull-out force after cyclic loading of the bicortical sacral pedicle screw through the S1 endplate were tested using human cadaveric specimens...

..For the short- and mid-term, cemented femoral component is recommended. However, a long-term randomised trial combined with a large cohort study or registry is needed...

..Biomechanical study into the association between genetic polymorphism in COL9A2 and mechanical properties of human nucleus pulposus...

..A review of the laboratory and clinical data for a new strontium-containing hydroxyapatite bioactive bone cement...

..023, R(2) = 0.68). This is the first study, to our knowledge, to evaluate the nanostructure of the individual collagen fibrils of the nucleus pulposus and its relationship with macroscale mechanical properties of the NP tissues...

..This study is, to our knowledge, the first report in the field of AAV-based BMP gene transfer and should be promising for clinical orthopaedic applications...

..What is more, bilateral ligation, which is worse than unilateral ligation, can lead to a significant decrease in the number and density of blood vessels of the spinal...

..These results would demonstrate the lower activities and muscle disuse atrophy of paraspinal muscles in the fusion region. While, higher muscular activities were found in the lower adjacent region, which may indicate muscle hypertrophy...

..To test the changes of the stiffness of the intact, released, and instrumented spines in an in vitro porcine model...

..A retrospective radiographic study on the type of surgically treated idiopathic scoliosis, with a prospective study on the reliability of the type-related fusion guide...

..Recently, Sky-bone expander, an alternative bone expander for PKP has been developed. The purpose of this study was to show our preliminary clinical outcomes of PKP with Sky-bone expander...

..They also indicate that the flexion angle of the spine at which the vertical compressive load is applied is an important factor in determining the MAF location; that is, the larger the flexion angle, the more anterior the MAF...