Research Topics
Species | Gregory ChengSummaryAffiliation: The Chinese University of Hong Kong Country: China Publications
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Publications
Eltrombopag for the treatment of immune thrombocytopeniaGregory Cheng
Dr Stanley Ho Medical Development Foundation, 9 F ICBC Tower, Macau Landmark, 555 Avenida da Amizade, Macau, China
Expert Rev Hematol 4:261-9. 2011....- Eltrombopag for management of chronic immune thrombocytopenia (RAISE): a 6-month, randomised, phase 3 studyGregory Cheng
Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China
Lancet 377:393-402. 2011..We aimed to compare the response to once daily eltrombopag versus placebo in patients with chronic immune thrombocytopenia during a 6-month period... - Use of convalescent plasma therapy in SARS patients in Hong KongY Cheng
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin, Hong Kong
Eur J Clin Microbiol Infect Dis 24:44-6. 2005..3% vs 15.6%; P<0.001) and among those who were PCR positive and seronegative for coronavirus at the time of plasma infusion (66.7% vs 20%; P=0.001)... - Warfarin dosing algorithm using clinical, demographic and pharmacogenetic data from Chinese patientsJoyce H S You
School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
J Thromb Thrombolysis 31:113-8. 2011..In conclusion, a genotype-guided dosing algorithm for warfarin therapy was developed for Chinese patients to explain 68% of dosage variation. The predicted doses differed from the actual doses by no more than 20% in 50% of patients... - Association of Vitamin K epoxide reductase complex 1 (VKORC1) variants with warfarin dose in a Hong Kong Chinese patient populationDavid L Veenstra
School of Pharmacy, The Chinese University of Hong Kong, Hong Kong
Pharmacogenet Genomics 15:687-91. 2005..To evaluate the association of VKORC1 genetic variants with warfarin dose requirements in a Hong Kong Chinese patient population... - The potential clinical and economic outcomes of pharmacogenetics-oriented management of warfarin therapy - a decision analysisJoyce H S You
Centre for Pharmacoeconomics Research, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong Shatin, N T, Hong Kong, China
Thromb Haemost 92:590-7. 2004..The cost-effectiveness of this treatment scheme depends on the relative cost and effectiveness of a pharmacogenetics-oriented intensified anticoagulation service comparing to the standard AC care... - Factors affecting the maintenance stable warfarin dosage in Hong Kong Chinese patientsVivian W Y Lee
School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
J Thromb Thrombolysis 20:33-8. 2005..Multiple factors can affect the anticoagulation effect of warfarin. The objective of this study was to determine the relationship between different clinical factors and outcomes of warfarin therapy in Hong Kong Chinese patients... - The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndromeDavid S Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Chest 125:1768-75. 2004..A case-controlled study to assess the effects of nasal continuous positive airway pressure (CPAP) on platelet activation in patients with obstructive sleep apnea (OSAS) syndrome... - Cost-effectiveness of two models of management for patients on chronic warfarin therapy--a Markov model analysisJoyce H S You
Centre for Pharmacoeconomics Research, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
Thromb Haemost 90:1106-11. 2003..In conclusion, the coordinated care provided by an anticoagulation clinic appears to be more cost-effective than routine medical care in the management of warfarin therapy from the perspective of public health organization in Hong Kong... - Simultaneous measurement of S-warfarin, R-warfarin, S-7-hydroxywarfarin and R-7-hydroxywarfarin in human plasma by liquid chromatography-tandem mass spectrometryZhong Zuo
School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR
J Pharm Biomed Anal 52:305-10. 2010..The method was successfully applied to analyze the steady state plasma concentrations of the four analytes in 30 patients... - Initial treatment of immune thrombocytopenic purpura with high-dose dexamethasoneYunfeng Cheng
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin NT, Hong Kong
N Engl J Med 349:831-6. 2003..The treatment was well tolerated. CONCLUSIONS: A four-day course of high-dose dexamethasone is effective initial therapy for adults with immune thrombocytopenic purpura... - Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysisRaymond S M Wong
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
BMJ 326:1358-62. 2003..CONCLUSIONS: Abnormal haematological variables were common among patients with SARS. Lymphopenia and the depletion of T lymphocyte subsets may be associated with disease activity... - Cross-reactivity of antibody against SARS-coronavirus nucleocapsid protein with IL-11Man Cheng
Department of Biochemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
Biochem Biophys Res Commun 338:1654-60. 2005..In a neutralization assay, IL-11-induced STAT 3 phosphorylation in rat intestinal epithelial IEC-18 cells was completely suppressed by the anti-N scFv clone L9N01... - A mathematical model for fresh frozen plasma transfusion strategies during major trauma resuscitation with ongoing hemorrhageAnthony M H Ho
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, PRC
Can J Surg 48:470-8. 2005..Meanwhile, coagulopathy remains a common occurrence during major trauma resuscitation and hemorrhage remains a major cause of traumatic deaths, suggesting that current coagulation factor replacement practices may be inadequate... - Successful treatment of pure red cell aplasia associated with systemic lupus erythematosus with oral danazol and steroidAlice Y K Chan
Rheumatology Unit, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
Rheumatol Int 25:388-90. 2005..Oral danazol 200 mg twice per day was started together with low-dose prednisolone therapy. There was no further recurrence of anemia 1 month after this combined therapy... - Relationship between patients' warfarin knowledge and anticoagulation controlElaine Othilia Y L Tang
School of Pharmacy, The Chinese University of Hong Kong, Hong Kong
Ann Pharmacother 37:34-9. 2003..20; p = 0.024). CONCLUSIONS: Patients' warfarin knowledge, a determinant of anticoagulation control, was generally poor. More attention should be given to the education of elderly and illiterate patients... - Use of herbal medicines by patients receiving warfarinRaymond S M Wong
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Drug Saf 26:585-8. 2003..Healthcare professionals play an important role in educating the patients and updating the list of herbal medicines that should be avoided by patients taking warfarin... - Incidence of Deep Vein Thrombosis in Hospitalized Chinese Medical Patients and the Impact of DVT ProphylaxisGregory Cheng
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong
Thrombosis 2011:629383. 2011..8%, 2%, and 1.7% for the year 2005, 2006, and 2007, respectively. The incidence was 1.1% for 2008 (P < .001). Conclusion. Proximal DVT was substantial in Chinese medical patients, and DVT prophylaxis might reduce such risk...