Research Topics
| Jian min SiSummaryAffiliation: Sun Yat-sen University Country: China Publications
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Detail Information
Publications
[An epidemiological and quality of life study of irritable bowel syndrome in Zhejiang province]Jian min Si
Department of Gastroenterology Institution, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China
Zhonghua Nei Ke Za Zhi 42:34-7. 2003..To evaluate the prevalence and quality of life (QOL)on irritable bowel syndrome (IBS) patients in Zhejiang province, and to evaluate the applying of Chinese version of the SF-36 questionnaire on IBS...
[The effect of muscovite on the quality of gastric ulcer healing]Jian min Si
Institute of Clinic Medicine Research of Sir Run Run Shaw, Zhejiang University, Hangzhou 310016, China
Zhongguo Zhong Yao Za Zhi 30:1536-41. 2005..To explore the effect of muscovite on the quality of gastric ulcer healing...
Quality of life and cost-effectiveness of combined therapy for reflux esophagitisJian min Si
Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China
J Zhejiang Univ Sci 4:602-6. 2003..To evaluate clinical, Quality of Life (QoL) and medical cost outcomes in patients with symptomatic reflux esophagitis (RE) receiving different "triple combination therapy"...
Irritable bowel syndrome consulters in Zhejiang province: the symptoms pattern, predominant bowel habit subgroups and quality of lifeJian min Si
Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 Qingchun Donglu, Hangzhou 310016, Zhejiang Province, China
World J Gastroenterol 10:1059-64. 2004..To investigate the pattern of symptoms, predominant bowel habits and quality of life (QOL) by the Chinese version of the SF-36 in irritable bowel syndrome (IBS) consulters in Zhejiang province...
Intestinal microecology and quality of life in irritable bowel syndrome patientsJian min Si
Department of Gastroenterology, Sir Run Run Shaw Affiliated Hospital of Zhejiang University, Hangzhou 310016, Zhejiang Province, China
World J Gastroenterol 10:1802-5. 2004..Because of the chronic course and frequent occurrence of the disease, IBS patients suffered much from it. So the quality of life (Qol) of IBS patients was also evaluated in this study...
Quality of gastric ulcer healing evaluated by endoscopic ultrasonographyJian min Si
Gastroenterology Laboratory, Institute of Clinical Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang Province, China
World J Gastroenterol 11:3461-4. 2005..To evaluate the quality of gastric ulcer healing after different antiulcer treatment by endoscopic ultrasonography (EUS)...
Trial of a novel endoscopic tattooing biopsy forceps on animal modelJian min Si
Department of Gastroenterology, Sir Run Run Shaw Hospital, Hangzhou 310016, Zhejiang Province, China
World J Gastroenterol 11:1859-61. 2005..To tattoo gastric mucosa with a novel medical device which could be used to monitor and follow-up gastric mucosal lesions...
[Mechanism of isinglass in prevention and treatment of chronic atrophic gastritis in rats]Jian min Si
Gastroenterologic Laboratory of Clinical Institute, Sir Run Run Shaw Hospital Affiliated to Medical School of Zhejiang University, Hangzhou 310016, China
Zhongguo Zhong Yao Za Zhi 29:666-70. 2004..To investigate the mechanism of isinglass in the prevention and treatment of chronic atrophic gastritis (CAG) in rats...
[Effect of mucosal protective on the quality of gastric ulcer healing]Yun Qian
Gastroenterology Laboratory, Sir Run Run Shaw Clinic Medical Research Institution, College of Medicine, Zhejiang University, Hangzhou 310016, China
Zhejiang Da Xue Xue Bao Yi Xue Ban 36:71-7. 2007..To explore the mucosal protective effect on the quality of gastric ulcer healing...
Morphological and pathologic changes of experimental chronic atrophic gastritis (CAG) and the regulating mechanism of protein expression in ratsLiang jing Wang
Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
J Zhejiang Univ Sci B 7:634-40. 2006..To study the pathologic change and molecular regulation in cell proliferation and apoptosis of gastric mucosa in rats with chronic atrophic gastritis (CAG), and evaluate the possible mechanisms...
Effect of H pylori infection and its eradication on hyperammo-nemia and hepatic encephalopathy in cirrhotic patientsShu jie Chen
Department of Gastroenterology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
World J Gastroenterol 14:1914-8. 2008..To investigate the relationship between H pylori infection, blood ammonia concentration and hepatic encephalopathy (HE), and the effect of H pylori eradication in cirrhotic patients...
Induction of experimental acute ulcerative colitis in rats by administration of dextran sulfate sodium at low concentration followed by intracolonic administration of 30% ethanolYan Chen
Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
J Zhejiang Univ Sci B 8:632-7. 2007....
[Effect of mica monomer granule on gastrin, somatostatin and G cells as well as D cells of gastric mucosa in CAG rat]Fang shi Zhu
Sir Run Run Shaw Clinical Medical Institute, Zhejiang University, Hangzhou 310016, China
Zhongguo Zhong Yao Za Zhi 29:554-8. 2004..To study regulative action of mica monomer granule preparation on gastrin (GAS), somatostatin (SS) and G cells as well as D cells of gastric mucosa in experimental chronic atrophic gastritis (CAG) rat...
[NOD2/CARD15 gene polymorphisms and susceptibility to Crohn's disease in Chinese Han population]Min Gao
GI Division of Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China
Zhonghua Nei Ke Za Zhi 44:210-2. 2005..Here we have evaluated the NOD2/CARD gene polymorphisms in Chinese patients to determine whether the gene is associated with susceptibility to CD in Chinese Han population...
Protective effects of heat shock protein70 induced by geranylgeranylacetone in atrophic gastritis in ratsWei Li Liu
Department of Gastroenterology and Zhejiang Key laboratory of Traditional Chinese Medicine TCM, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310012, China
Acta Pharmacol Sin 28:1001-6. 2007..To investigate the effect of geranylgeranylacetone (GGA) on the progression of atrophic gastritis in rats and its potential mechanism...
[Small interfering RNA inhibits cell proliferation in gastric cancer cell lines highly expressing RegI?]Xiao Feng Lu
Laboratory of Digestive Disease, Clinical Institution of Sir Run Run Shaw Hospital, Zhejiang University and Key Laboratory of Biotherapy of Zhejiang Province, Hangzhou 310006, China
Zhejiang Da Xue Xue Bao Yi Xue Ban 40:57-63. 2011..To investigate the effect of small interfering RNA on cell proliferation and apoptosis in gastric cancer cell lines with high expression of RegI?...
Ascorbic acid alleviates pancreatic damage induced by dibutyltin dichloride (DBTC) in ratsXin Liang Lu
Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
Yonsei Med J 48:1028-34. 2007..The aim of this study was to investigate the effects of ascorbic acid on oxidative capacity and pancreatic damage in experimental CP...
[Relationship between Helicobacter pylori negative chronic superficial gastritis and functional dyspepsia: are they the same disease?]Zheng ren Luo
Zhejiang University Gastroenterology Institution, Sir RunRun Shaw Hospital, Hangzhou 310016, China
Zhonghua Nei Ke Za Zhi 42:476-8. 2003..To discriminate between Helicobacter pylori (Hp) negative chronic superficial gastritis and functional dyspepsia (FD) from therapeutic point of view...
Curcumin reverses chemoresistance of human gastric cancer cells by downregulating the NF-?B transcription factorLiang Liang Yu
Department of Gastro enterology, Sir Run Run Shaw Affiliated Hospital of Zhejiang University, 3 East Qingchun Road, Hangzhou 310016, Zhejiang, PR China
Oncol Rep 26:1197-203. 2011..Curcumin potentiates the antitumor effects of chemotherapeutics in gastric cancer by suppressing NF-?B and NF-?B-regulated anti-apoptotic genes...
A novel mouse model for colitis-associated colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sulfate sodiumJian guo Wang
Department of Gastroenterology, Sir Run Run Shaw Hospital, Hangzhou 310016, Zhejiang Province, China
World J Gastroenterol 10:2958-62. 2004..To develop an efficient animal colitis-associated carcinogenesis model and to detect the expression of beta-catenin and p53 in this new model...
[Construction of COL1A1 short hairpin RNA vector and its effect on cell proliferation and migration of gastric cancer cells]Ai Qing Li
Gastroenterology Laboratory, Clinic Medical Research Institution, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China
Zhejiang Da Xue Xue Bao Yi Xue Ban 39:257-63. 2010..To construct COL1A1-targeted short hairpin RNA (shRNA) vector with pSilencer 4.1-CMV neo siRNA expression vector and to evaluate its effect on proliferation and migration of gastric cancer BGC-823 cells in vitro...
Genetic susceptibility to ulcerative colitis in the Chinese Han ethnic population: association with TNF polymorphismsQian Cao
Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China
Chin Med J (Engl) 119:1198-203. 2006..We investigate the association between TNF promoter polymorphisms and susceptibility to ulcerative colitis (UC) in the Chinese Han ethnic population...
Chronic gastritis rat model and role of inducing factorsZun Xiang
Department of Gastroenterology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
World J Gastroenterol 10:3212-4. 2004..To establish an experimental animal model of chronic gastritis in a short term and to investigate the effects of several potential inflammation-inducing factors on rat gastric mucosa...
Quality of care for patients with inflammatory bowel disease in East ChinaQin Zhu
Department of Gastoenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
World J Gastroenterol 14:612-6. 2008..To investigate the quality of care for a hospital based-cohort of patients with inflammatory bowel disease (IBD) from East China according to the current practice guidelines...
Protective effect of salvianolic acid B on chronic pancreatitis induced by trinitrobenzene sulfonic acid solution in ratsXin Liang Lu
Departments of Gastroenterology, Second Affiliated Hospital, Zhejiang University, Hangzhou, China
Pancreas 38:71-7. 2009..To investigate the effects of salvianolic acid B (Sal-B) on pancreatic damage in experimental chronic pancreatitis...
A probiotic treatment containing Lactobacillus, Bifidobacterium and Enterococcus improves IBS symptoms in an open label trialYu-Jing Fan
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China
J Zhejiang Univ Sci B 7:987-91. 2006..Thereafter conditions remained stable for 2 weeks. That improvement may be associated with alterations in gastrointestinal flora...
[Prevention and treatment of chronic atrophic gastritis in rats with isinglass]Miao Xu
Gastroenterologic Laboratory of Clinical Institute, Sir Run Run Shaw Hospital Affiliated to Medical School of Zhejiang University, Hangzhou 310016, China
Zhongguo Zhong Yao Za Zhi 29:251-4. 2004..01). They were very close to normal control group (P > 0.05). CONCLUSION: Isinglass can prevent the gastric mucosal atrophy in the CAG model and can improve and cure the gastric mucosal atrophy of the SD rats with GAG...
Akt associates with nuclear factor kappaB and plays an important role in chemoresistance of gastric cancer cellsLiang Liang Yu
Department of Gastroenterology, Sir Run Run Shaw Affiliated Hospital of Zhejiang University, Hangzhou 310016, Zhejiang Province, PR China
Oncol Rep 24:113-9. 2010..NF-kappaB is a downstream target of Akt...
[Construction of RegI? over-expression vector and its effect on proliferation and apoptosis of gastric cancer cells]Qun yan Zhou
Gastroenterology Laboratory, Clinic Medical Research Institution, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China
Zhejiang Da Xue Xue Bao Yi Xue Ban 39:499-505. 2010..To construct RegI? over-expression vector and to evaluate the effect of RegI? on the proliferation and apoptosis of gastric cancer MKN28 cells in vitro...
[Mechanisms of muscovite on gastric mucosal protective effect]Yun Qian
Gastroenterology Laboratory of Sir Run Run Shaw Clinic Medical Center, Zhejiang University, Hangzhou 310016, China
Zhongguo Zhong Yao Za Zhi 29:781-5. 2004..It has gastric mucosal protective effect by improving excretion of mucus and synthesis of PGE2 in gastric mucosa, restraining gastric acid, reversing of intestinal metaplasia and decreasing inflammation cells...
[Effects of EGF/EGFR expression on atrophic gastritis in rats]Qian Cao
The Sir Run Run Shaw Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310016, China
Zhejiang Da Xue Xue Bao Yi Xue Ban 32:235-6. 2003..01]. CONCLUSION: The study demonstrates an association of high levels of EGF and positive EGFR expression in CAG rats. Further studies are necessary to clarify whether EGF/EGFR play a significant role in the pathogenesis of CAG...
Regulative effect of traditional Chinese medicine on gene-expression related to precancerous lesion of gastric cancerFang shi Zhu
Zhejiang University, Sir Run Run Shaw Hospital of College Medicine, Hangzhou, China
Chin J Integr Med 11:76-80. 2005....
Therapeutic effects of rectal administration of muscovite on experimental colitis in ratsYan Chen
Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
J Gastroenterol Hepatol 24:912-9. 2009..The aim of this study was to investigate whether rectal administration of muscovite can ameliorate colonic inflammation in a rat model of experimental colitis, and its possible mechanism...
ZIC1 is downregulated through promoter hypermethylation in gastric cancerLiang jing Wang
Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
Biochem Biophys Res Commun 379:959-63. 2009..01). Our results revealed ZIC1 as a novel candidate tumor suppressor gene downregulated through promoter hypermethylation in gastric cancer...
[Intestinal mucosa protection of muscovite n ulcerative colitis in rats]Liang-Jing Wang
Department of Gastroenterology, Second Affiliated Hospital Zhejiang University College of Medicine, Hangzhou, China
Zhongguo Zhong Yao Za Zhi 30:1840-4. 2005..01). CONCLUSION: Muscovite has the effect of mucosal protection by attenuating the inflammation of colonic mucosa and decreasing the activity of MPO...
Expression of growth hormone and its receptor in chronic atrophic gastritis and its clinical significanceJian-min Si
Department of Gastroenterology of Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou 310016, Zhejiang Province, China
World J Gastroenterol 10:2908-10. 2004..There is no significant change of GH in gastric carcinorma patients, GH dose not play a role in the pathogenesis of gastric cancer...
[The effects of Helicobacter pylori infection on hyperammonaemia and hepatic encephalopathy in cirrhotic patients]Liang-Jing Wang
Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
Zhonghua Nei Ke Za Zhi 45:654-7. 2006..05). CONCLUSIONS: Hp infection was an important factor of inducing with high blood ammonia concentration and hepatic encephalopathy in cirrhotic patients. Hp eradication may be helpful for treatment and prevention of HE...
Clinical presentation of inflammatory bowel disease: a hospital based retrospective study of 379 patients in eastern ChinaQian Cao
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
Chin Med J (Engl) 118:747-52. 2005..The ethnic and geographic differences may give important clues to the aetiology of IBD...
[Effect of mica granule on the expression of gene-protein associated with cancer in gastric mucosa tissue of chronic atrophic gastritis rats]Fang shi Zhu
Academy of Traditional Chinese Medicine of Jiangsu Province, Nanjing 210028, China
Zhongguo Zhong Yao Za Zhi 31:312-6. 2006..To research the regulative effect of mica monomer granule preparation on the expression of gene associated with cancer in gastric mucosa tissue of experimental chronic atrophic gastritis (CAG) rats...
Effect of mica monomer powder on chief and parietal cells as well as G and D cells in gastric mucosa of chronic atrophic gastritis in ratsFang shi Zhu
Academy of Traditional Chinese Medicine of Jiangsu Province, Nanjing, China
Chin J Integr Med 14:111-6. 2008..To study the regulative action of mica monomer powder preparation on the chief and parietal cells as well as G and D cells in the gastric mucosa of the experimental atrophic gastritis (CAG) rats...
[Pharmacological effect and clinical application of protective agents of gastric mucosa]Jian-min Si
Zhonghua Yi Xue Za Zhi 87:2955-7. 2007
[Attach importance to protection of gastric mucosa by growth factor]Jian-min Si
Zhonghua Yi Xue Za Zhi 85:2744-5. 2005
