Research Topics
| Yiming ShaoSummaryCountry: China Publications
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Publications
AIDS epidemic at age 25 and control efforts in ChinaYiming Shao
National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, 27 Nanwei Road, Xuanwu District, Beijing, China
Retrovirology 3:87. 2006..Only with a scientific approach and evidence-based strategy, can China seize the opportunity to stop AIDS at an early stage...
Co-receptor usage and prediction of V3 genotyping algorithms in HIV-1 subtype B' from paid blood donors experienced anti-retroviral therapy in Chinese central provinceShuiling Qu
State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Virol J 7:280. 2010..This study explored co-receptor usage and prediction of V3 genotyping algorithms in HIV-1 subtype B' from paid blood donors experienced anti-retroviral therapy in Chinese central province in order to design effectively therapeutic regimen...
Replication and drug resistant mutation of HIV-1 subtype B' (Thailand B) variants isolated from HAART treatment individuals in ChinaJianping Sun
State Key Laboratory for Infection Disease Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention China CDC, Beijing 100050, PR China
Virol J 6:201. 2009..Understanding the replication and drug resistant mutation of HIV-1 variants isolated from HAART treatment individuals of China could help to design appropriate therapeutic strategies for these individuals...
Broader HIV-1 neutralizing antibody responses induced by envelope glycoprotein mutants based on the EIAV attenuated vaccineLianxing Liu
State Key Laboratory for Infectious Diseases Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Changping District, Beijing 102206, China
Retrovirology 7:71. 2010..The purpose of the modification was to enhance the immunogenicity of the HIV Env...
Phenotypic and genotypic characterization of human immunodeficiency virus type 1 CRF07_BC strains circulating in the Xinjiang Province of ChinaLiying Ma
State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, PR China
Retrovirology 6:45. 2009..The aim of this study is to characterize the genotypic and phenotypic properties of HIV-1 CRF07_BC isolates in comparison with those of the subtype B' (Thailand B) which is prevalent in the former plasma donors (FPDs) in China...
Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC)Jianping Chen
State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Retrovirology 4:62. 2007....
A sex-role-preference model for HIV transmission among men who have sex with men in ChinaJie Lou
Department of Mathematics, Shanghai University, 99 Shangda Road Shanghai, 200444, PR China
BMC Public Health 9:S10. 2009..China has a sizable population of MSM, including gay, bisexual men, money boys and some rural workers. So reducing HIV infection in this population is an important component of the national HIV/AIDS prevention and control program...
Inhibitory activity of 9-phenylcyclohepta[d]pyrimidinedione derivatives against different strains of HIV-1 as non-nucleoside reverse transcriptase inhibitorsYang Huang
State Key Laboratory for Infection Disease Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, Chinese Center for Disease Control and Prevention CDC, China
Virol J 8:230. 2011..Therefore, a series of novel compounds, 9-phenylcyclohepta[d]pyrimidinedione derivatives (PCPs), were designed based on the chemical structure of TNK-651, to detect anti-HIV-1 activity...
HCV coinfection associated with slower disease progression in HIV-infected former plasma donors naïve to ARTXiaoyan Zhang
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, China CDC, Beijing, China
PLoS ONE 3:e3992. 2008..This study aims to define the influence of HCV infection on the replication of HIV-1 and the disease progression in HIV-infected former plasma donors (FPDs) naïve to ART...
Characterization of HIV-1 subtypes and viral antiretroviral drug resistance in men who have sex with men in Beijing, ChinaXiaoyan Zhang
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, China CDC, Beijing 100050, China
AIDS 21:S59-65. 2007..To characterize the HIV subtypes prevalent among men who have sex with men (MSM) in Beijing and to perform baseline genotypic analysis of anti-HIV drug resistance in this population...
Correlates of incident infections for HIV, syphilis, and hepatitis B virus in a cohort of men who have sex with men in BeijingDongliang Li
Chaoyang Center for Disease Control and Prevention, Xuanwu District, Beijing, P R China
AIDS Patient Care STDS 24:595-602. 2010..The findings of this study underscore the urgent needs for a comprehensive intervention strategy to curtail the rapid spread of HIV, syphilis, and HBV...
Willingness of Chinese injection drug users to participate in HIV vaccine trialsLu Yin
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, Chinese Center for Disease Control and Prevention China CDC, 27 Nanwei Road, Xuanwu District, Beijing 100050, China
Vaccine 26:762-8. 2008..Chinese injection drug users (IDUs) may be a proper candidate population for HIV vaccine trials...
Identification of subtype B, multiple circulating recombinant forms and unique recombinants of HIV type 1 in an MSM cohort in ChinaWanhai Wang
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China
AIDS Res Hum Retroviruses 24:1245-54. 2008....
Dynamic analysis of genetic diversity of gag and env regions of HIV-1 CRF07_BC recombinant in intravenous drug users in Xinjiang Uvghur Autonomous Region, ChinaShengya Liu
State Key Laboratory for Infectious Diseases Prevention and Control, National Center for AIDS STD Control and Prevention, Beijing, China
Arch Virol 153:1233-40. 2008..In addition, env and gag gene diversity increased over time. The observed patterns and associations may enhance our understanding of HIV-1 evolution...
Genotypic and phenotypic cross-drug resistance of harboring drug-resistant HIV type 1 subtype B' strains from former blood donors in central Chinese provincesLiying Ma
State Key Laboratory for Infection Disease Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, Chinese Center for Disease Control and Prevention, Beijing, China
AIDS Res Hum Retroviruses 26:1007-13. 2010....
Incidence of HIV, hepatitis C and hepatitis B viruses among injection drug users in southwestern China: a 3-year follow-up studyYuhua Ruan
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
AIDS 21:S39-46. 2007..To investigate the incidence rates of HIV, hepatitis C virus (HCV), and hepatitis B virus (HBV) among injection drug users (IDU) in a drug trafficking city in southwest China...
Willingness to be circumcised for preventing HIV among Chinese men who have sex with menYuhua Ruan
State Key Laboratory for Infectious Disease Prevention and Control and National Center for AIDS STD Control and Prevention NCAIDS, Chinese Center for Disease Control and Prevention China CDC, Beijing, China
AIDS Patient Care STDS 23:315-21. 2009..The study suggests that circumcision is uncommon among Chinese MSM. Considerable community education will be needed in circumcision advocacy among MSM in China. A clinical trial for efficacy among MSM should be considered...
High HIV risk among Uigur minority ethnic drug users in northwestern ChinaLi Zhang
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Trop Med Int Health 13:814-7. 2008..To assess differences of HIV risk between ethnicities in northwestern China...
Increased NKG2A found in cytotoxic natural killer subset in HIV-1 patients with advanced clinical statusRuijun Zhang
State Key Laboratory for Infectious Diseases Prevention and Control, National Center for AIDS STD Control and Prevention, China CDC, Beijing, China
AIDS 21:S9-17. 2007..To investigate the expression of NKG2A on cytotoxic natural killer (NK) cells in HIV-1-infected patients...
Comparison of immunogenicity between codon optimized HIV-1 Thailand subtype B gp140 and gp145 vaccinesYanmin Wan
State Key Laboratory for Infectious Diseases Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, China CDC, 27 Nanwei Road, Xuanwu District, Beijing 100050, China
Vaccine 25:4949-59. 2007..However, it remains to be determined that how these observations are relevant to the neutralization of antibody activities...
Predictors of unprotected sex among men who have sex with men in Beijing, ChinaXinxu Li
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Southeast Asian J Trop Med Public Health 39:99-108. 2008..Further education, condom promotion, and prevention of sexually transmitted infections should be intensified urgently to combat the rising HIV epidemic among MSM in Beijing...
Genetic characterization analysis of the tat exon-1 region of HIV type 1 CRF07_BC strains in ChinaZhiming Fang
Division of Virology and Immunology, State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS STD Prevention and Control, Chinese Center for Disease Control and Prevention, Xuanwu District, Beijing 100050, P R China
AIDS Res Hum Retroviruses 26:359-63. 2010..6%) and R46F (90.3%), as compared with subtype B' strains in Thailand. The analysis of the sequences provides some valuable information for an exploration of the predominance of the HIV-1 CRF07_BC epidemic...
Susceptibility of HIV-1 subtypes B', CRF07_BC and CRF01_AE that are predominantly circulating in China to HIV-1 entry inhibitorsXiaoling Yu
State Key Laboratory for Infection Disease Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, Chinese Center for Disease Control and Prevention China CDC, Beijing, China
PLoS ONE 6:e17605. 2011..The B', CRF07_BC and CRF01_AE are the predominant HIV-1 subtypes in China. It is essential to determine their baseline susceptibility to HIV entry inhibitors before these drugs are used in China...
HIV incidence and factors contributed to retention in a 12-month follow-up study of injection drug users in Sichuan Province, ChinaYuhua Ruan
National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing
J Acquir Immune Defic Syndr 39:459-63. 2005..This study also suggested that HIV is spreading rapidly to more geographic areas along drug-trafficking routes in China, and a short-term follow-up rate may predict a long-term retention rate in this IDU cohort...
Risk factors for death in subjects with transfusion-related HIV infection in rural ChinaYuhua Ruan
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
AIDS Patient Care STDS 22:95-7. 2008
CD8+ cell noncytotoxic antiviral response in long-term HIV-1 infected former blood donors in ChinaLin Yuan
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Curr HIV Res 7:437-40. 2009..Our findings in long term infected FBDs confirm the clinical relevancy of CNAR and suggest that CNAR could be an additional marker to help determine the optimal time for starting therapy in HIV infected person...
Syphilis among female sex workers in southwestern China: potential for HIV transmissionYuhua Ruan
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Sex Transm Dis 33:719-23. 2006....
Analysis of putative N-linked glycosylation sites and variable region of envelope HIV-1 CRF07_BC recombinant in intravenous drug users in Xinjiang Autonomous Region, ChinaShengya Liu
State Key Laboratory for Infectious Diseases Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Xuan Wu District, Beijing 100050, China
AIDS Res Hum Retroviruses 24:521-7. 2008..We argue that limited PNGSs and the length of variable loops may be involved in selective transmission and escape...
Construction and characterization of an infectious molecular clone of HIV type 1 CRF07_BCZhefeng Meng
State Key Laboratory for Infection Diseases Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, Chinese Center for Disease Control and Prevention China CDC, Beijing, P R China 100050
AIDS Res Hum Retroviruses 24:259-64. 2008..This study has produced the first isolation of the HIV-1 CRF07_BC DNA clone and has provided a versatile molecular model for research focusing on the biological properties of this subtype...
Virologic outcomes of first-line HAART and associated factors among Chinese patients with HIV in three sentinel antiretroviral treatment sitesYuhua Ruan
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, 27 Nanwei Road, Beijing, China
Trop Med Int Health 15:1357-63. 2010..To evaluate HIV drug resistance (HIVDR) among Chinese patients with HIV receiving first-line highly active antiretroviral therapy (HAART)...
Genotypic analysis of the protease and reverse transcriptase of HIV type 1 isolates from recently infected injecting drug users in western ChinaLingjie Liao
Division of Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
AIDS Res Hum Retroviruses 23:1062-5. 2007..Further studies are needed to determine the impact of genetic features of CRF07-BC on antitretroviral susceptibility and evolution of drug resistance mutations...
Co-infection with HIV and hepatitis C virus in former plasma/blood donors: challenge for patient care in rural ChinaHan-zhu Qian
National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
AIDS 20:1429-35. 2006..4; 95% CI, 1.2-14.0; P = 0.04) were associated with HIV and/or HCV infections. CONCLUSIONS: HIV and HCV infections are now prevalent in these Chinese communities. HIV projects should consider screening and care for HCV co-infection...
Mucosal priming with PEI/DNA complex and systemic boosting with recombinant TianTan vaccinia stimulate vigorous mucosal and systemic immune responsesXianggang Huang
State Key Laboratory for Infectious Diseases Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, China CDC, Beijing, China
Vaccine 25:2620-9. 2007..These results demonstrate that the combination of intranasal priming with PEI/DNA complexes and systemic boosting with rTTV is a preferable regimen for induction of both T-cell and humoral immune responses...
The prevalence of transmitted antiretroviral drug resistance in treatment-naive HIV-infected individuals in ChinaLingjie Liao
National Center for AIDS STD Control and Prevention, Beijing, China
J Acquir Immune Defic Syndr 53:S10-4. 2010..Transmission of HIV drug resistance (TDR) gives rise to reduced efficacy of initial antiretroviral treatment and has become a public health concern...
Relationship between syphilis and HIV infections among men who have sex with men in Beijing, ChinaYuhua Ruan
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Sex Transm Dis 34:592-7. 2007..Little is known about risk of HIV and other STDs among men who have sex with men (MSM) in China...
Nonfatal overdose among heroin users in southwestern ChinaLu Yin
National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, and State Key Laboratory for Infectious Disease Prevention and Control, Beijing, China
Am J Drug Alcohol Abuse 33:505-16. 2007..To evaluate the prevalence of and risk factors for nonfatal overdose among heroin users in southwestern China...
Sexual mixing patterns among social networks of HIV-positive and HIV-negative Beijing men who have sex with men: a multilevel comparison using roundtable network mappingYuhua Ruan
State Key Laboratory for Infectious Disease Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing, China
AIDS Care 23:1014-25. 2011....
Association between Vgamma2Vdelta2 T cells and disease progression after infection with closely related strains of HIV in ChinaHaishan Li
State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Clin Infect Dis 46:1466-72. 2008..We performed a cross-sectional study involving HIV-infected former blood donors and assessed the association between Vgamma2Vdelta2 T cells and markers of disease progression...
Conservancy of the ?4?7 integrin mimotope in the V2 domain of HIV type 1 CRF07_BC compared to subtype B' strains in ChinaXiang He
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, China CDC, Beijing, China
AIDS Res Hum Retroviruses 27:1127-33. 2011..In this study, we compared the ?(4)?(7) binding sites of two HIV-1 subtypes prevalent in China and found that the tripeptide binding domain of ?(4)?(7) was more diverse in subtype B' strains than in CRF07_BC...
Estimating the number of people living with HIV/AIDS in China: 2003-09Ning Wang
Chinese Center for Disease Control and Prevention, Beijing, China
Int J Epidemiol 39:ii21-8. 2010..Subsequent national estimation exercises were carried out in 2005, 2007 and 2009. We describe these estimation processes and present the results of China's HIV/AIDS estimation exercises from 2003 to 2009...
Factors associated with HIV virologic failure among patients on HAART for one year at three sentinel surveillance sites in ChinaXia Wang
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Curr HIV Res 9:103-11. 2011..Emerging HIV drug resistance (HIVDR) poses a growing threat to the long-term success and durability of highly active antiretroviral therapy (HAART)...
Sequential priming and boosting with heterologous HIV immunogens predominantly stimulated T cell immunity against conserved epitopesJianqing Xu
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, Beijing, China
AIDS 20:2293-303. 2006..The effort to develop an effective preventive vaccine against HIV-1 infection is challenged by the wide genetic diversity of HIV-1 among different isolates...
Characterization of five nearly full-length genomes of early HIV type 1 strains in Ruili city: implications for the genesis of CRF07_BC and CRF08_BC circulating in ChinaZhaozhu Qiu
National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
AIDS Res Hum Retroviruses 21:1051-6. 2005..The sequences undoubtedly lead us to a better understanding of the emergence of CRF07_BC and CRF08_BC...
A pilot study on an attenuated Chinese EIAV vaccine inducing broadly neutralizing antibodiesQinglai Meng
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, 102206, Beijing, China
Arch Virol 156:1455-62. 2011..These data indicate that EIAVFDDV induced broadly neutralizing antibodies, which might confer enhanced protection of vaccinees from infection by the challenge virus...
Flow cytometric characterization of T lymphocyte subsets in the peripheral blood of Chinese rhesus macaques: normal range, age- and sex-related differencesChen Li Qiu
State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS STD Control and Prevention, China CDC, 27 Nanwei Road, Xuanwu District, Beijing 100050, PR China
Vet Immunol Immunopathol 124:313-21. 2008..This study provided basic information about blood cell count and T lymphocyte subsets in Chinese rhesus macaques. It may be useful for comparative studies using Indian and Chinese rhesus macaques...
Hepatitis C virus infection in former commercial plasma/blood donors in rural Shanxi Province, China: the China Integrated Programs for Research on AIDSHan-zhu Qian
National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing
J Infect Dis 192:1694-700. 2005..China has taken steps to halt illegal plasma collection and to improve blood-banking methods. However, there will be an ongoing challenge to care for patients with HCV infection, even as its incidence decreases...
Molecularly cloned SHIV-CN97001: a replication-competent, R5 simian/human immunodeficiency virus containing env of a primary Chinese HIV-1 clade C isolateQiang Liu
National Center for AIDS STD Control and Prevention, China CDC, Beijing, China
J Med Primatol 40:427-36. 2011..In China, the prevalent HIV strains comprise a circulating recombinant form, BC (CRF07_BC), in which the envelope belongs to subtype C...
Community-based survey of HIV transmission modes among intravenous drug users in Sichuan, ChinaYuhua Ruan
Division of Virology and Immunology, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Sex Transm Dis 31:623-7. 2004..Further seroepidemiologic prospective cohort studies should be conducted to clarify the impact of syphilis and high-risk sexual behaviors on HIV transmission through unprotected sexual intercourse...
Incidence of HIV-1, syphilis, hepatitis B, and hepatitis C virus infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men in Beijing, ChinaYuhua Ruan
State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS sexually transmitted disease Control and Prevention, Chinese Center for Disease Control and Prevention China CDC, Beijing, P R China
J Acquir Immune Defic Syndr 52:604-10. 2009..To investigate the incidence of HIV-1, syphilis, hepatitis B virus (HBV), and hepatitis C virus (HCV) infections and predictors associated with retention in a 12-month follow-up study among men who have sex with men (MSM) in Beijing, China...
Genetic and temporal dynamics of human immunodeficiency virus type 1 CRF07_BC in Xinjiang, ChinaRuolei Xin
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, China CDC, Beijing 100050, PR China
J Gen Virol 90:1757-61. 2009..3x10(-3) substitutions per site per year in the env gene. After 5-6 years of the epidemic (1997-2002), the transmission rate of CRF07_BC in Xinjiang slowed down, although CRF07_BC infection remained at a high prevalence...
Alteration of serotonin transporter messenger RNA level in the peripheral blood mononuclear cells from simian/human immunodeficiency virus infected Chinese rhesus macaques (Macaca mulatta)Kai Yu
State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS STD Control and Prevention, China CDC, Beijing 100050, PR China
Brain Behav Immun 24:298-305. 2010..Besides, this study provided a basis for quantitative analysis of SERT gene expression under effects of host and environmental factors, such as 5-HTTLPR genotypes, SERT targeting drugs or other infectious agents...
Induction of primary virus-cross-reactive human immunodeficiency virus type 1-neutralizing antibodies in small animals by using an alphavirus-derived in vivo expression systemMing Dong
Departments of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda 20814, USA
J Virol 77:3119-30. 2003..These findings support the expectation that induction of highly cross-reactive HIV-1 primary virus-neutralizing activity by vaccination may be realized...
The epidemic origin and molecular properties of B': a founder strain of the HIV-1 transmission in AsiaXiang Deng
HIV Molecular Epidemiology and Virology Research Group, The State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Science, Wuhan, China
AIDS 22:1851-8. 2008..To clarify the epidemic origin and molecular properties of the B' subtype that is an important strain in the HIV-1 epidemic in Asia...
HIV prevalence among injection drug users in rural Guangxi ChinaWei Liu
Guangxi Centers for Disease Control and Prevention, Nanning, China
Addiction 101:1493-8. 2006..62; 95% CI 1.08, 2.43). CONCLUSIONS: HIV infection among IDU in Guangxi, one of China's major HIV epidemic regions, is high and the infection occurs predominantly among older IDU males who share rinse water...
Demographic characteristics and risk behaviors associated with HIV positive injecting drug users in Xinjiang, ChinaYuanzhi Zhang
Xinjiang Center for Disease Control and Prevention, 48 Beijing South Road, Urumqi 830011, China
J Infect 54:285-90. 2007....
Polymorphism of the protease and reverse transcriptase and drug resistance mutation patterns of HIV-1 subtype B prevailing in ChinaShulin Jiang
J Acquir Immune Defic Syndr 42:512-4. 2006
Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelopeLan Wu
Vaccine Research Center, NIAID, National Institutes of Health, Room 4502, Bldg. 40, MSC-3005, 40 Convent Drive, Bethesda, MD 20892-3005, USA
Vaccine 24:4995-5002. 2006....
Molecular cloning and in vitro evaluation of an infectious simian-human immunodeficiency virus containing env of a primary Chinese HIV-1 subtype C isolateYingYun Wu
College of Life Sciences, Nankai University, Tianjin, China
J Med Primatol 34:101-7. 2005..The resulting chimeric SHIV-XJ02170 was infectious in human, rhesus monkey and cynomolgus monkey peripheral blood mononuclear cells (PBMC) and used CCR5 exclusively as coreceptor...
Biochemical and HIV-1 coreceptor properties of K26R, a new CCR5 Variant in China's Sichuan populationLiying Ma
INSERM U543, CHU Pitie Salpetriere, 75013 Paris, France
J Acquir Immune Defic Syndr 39:38-43. 2005..We observed that K26R displayed alteration in MIP1-beta/CCL4 and RANTES/CCL5 ligand binding and exhibited a slightly decrease for HIV coreceptor properties...
Simple subtyping assay for human immunodeficiency virus type 1 subtypes B, C, CRF01-AE, CRF07-BC, and CRF08-BCMin Wei
Division of Virology and Immunology, National Center for AIDS/STD Prevention and Control, China Center for Disease Prevention and Control, Beijing, 100050 People's Republic of China
J Clin Microbiol 42:4261-7. 2004..The average reproducibility was 96.0% for subtype B, 96.7% for subtype C, and 95.0% for CRF01-AE. We have developed a simple, rapid, and low cost assay for screening subtypes B, C, CRF01-AE, CRF07-BC, and CRF08-BC in China...
Medicine. The need for a global HIV vaccine enterpriseRichard D Klausner
Bill and Melinda Gates Foundation, Seattle, WA 98102, USA
Science 300:2036-9. 2003....
Genotype and phenotype patterns of drug-resistant HIV-1 subtype B' (Thai B) isolated from patients failing antiretroviral therapy in ChinaLiying Ma
State Key Laboratory for Infection Diseases Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, Chinese Center for Disease Control and Prevention China CDC, People s Republic of China
J Acquir Immune Defic Syndr 44:14-9. 2007..Because NVP and AZT can induce high resistances in these patients, these two drugs should be replaced with others more effective NNRTIs and NRTIs...
Human leukocyte antigen class I and class II allele frequencies and HIV-1 infection associations in a Chinese cohortShu Li
Vaccine Laboratory, Nankai University, Tianjin, China
J Acquir Immune Defic Syndr 44:121-31. 2007..These data contribute to the database of allele frequencies and associations with HIV infection in the Chinese population...
HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, ChinaYuanzhi Zhang
Xinjiang Center for Disease Control and Prevention, Urumqi, China
Int J Infect Dis 11:318-23. 2007..To determine HIV seroincidence, study participant retention rate, and baseline predictors of HIV incidence and study retention among high-risk injection drug users (IDUs) in Xinjiang, China...
Optimization of the oligonucleotide ligation assay, a rapid and inexpensive test for detection of HIV-1 drug resistance mutations, for non-North American variantsIngrid A Beck
Division of Infectious Diseases and Virology, University of Washington, Seattle, WA, USA
J Acquir Immune Defic Syndr 48:418-27. 2008....
Modeling and prediction of HIV in China: transmission rates structured by infection agesYican Zhou
Department of Applied Mathematics, Xi an Jiaotong University, Xi an, 710049 China
Math Biosci Eng 5:403-18. 2008....
Pathogenicity and immunogenicity of recombinant Tiantan Vaccinia Virus with deleted C12L and A53R genesKaifan Dai
National Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
Vaccine 26:5062-71. 2008..These data suggest that deletion of the cytokine viroceptor gene is feasible to obtain a safer and replication-competent TV vector for vaccination and immunotherapy...
Genetic diversity and drug resistance of human immunodeficiency virus type 1 (HIV-1) strains circulating in ShanghaiPing Zhong
Department of AIDS and STD, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
AIDS Res Hum Retroviruses 23:847-56. 2007..It is believed that this information may help to guide recommendations for diagnostic assays, vaccine design, and antiretroviral regimen strategies in China...
Risk factors of HIV infection and prevalence of co-infections among men who have sex with men in Beijing, ChinaXiaoxi Zhang
Chaoyang District Center for AIDS STD Control and Prevention, Beijing 100021, China
AIDS 21:S53-7. 2007..To investigate risk factors related to HIV infection and the prevalence of selected infections, especially sexually transmitted infections (STI) among men who have sex with men (MSM)...
Impact of methadone on drug use and risky sex in ChinaHan Zhu Qian
Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
J Subst Abuse Treat 34:391-7. 2008..Data suggest positive, short-term impact on these important behaviors, but further studies are needed to examine the long-term impact of methadone treatment on disease rates...
Genetic characterization of three newly isolated CRF07_BC near full-length genomes in ChinaZhefeng Meng
Division of Virology and Immunology, State Key Laboratory for Infectious Disease Control and Prevention, National Center for AIDS STD Control and Prevention, China CDC, Beijing 100050, PR China
AIDS Res Hum Retroviruses 23:1049-54. 2007..The analysis of the sequences provides some valuable information on the investigation of the epidemiology and on vaccine development...
Extensively cross-reactive anti-HIV-1 neutralizing antibodies induced by gp140 immunizationPeng Fei Zhang
Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Proc Natl Acad Sci U S A 104:10193-8. 2007..Neutralization was IgG-mediated and HIV-1-specific. These results demonstrate that induction of truly broad spectrum neutralizing antibodies is an achievable goal in HIV-1 vaccine development...
HIV incidence, retention, and changes of high-risk behaviors among rural injection drug users in Guangxi, ChinaLiu Wei
Guangxi Centers for Disease Control and Prevention, Nanning, China
Subst Abus 27:53-61. 2006..CONCLUSIONS: HIV incidence is high among IDU in Guangxi, China despite a self-reported decrease in some high risk behaviors over the course of the study...
[Clinical study on treatment of HIV infected persons based on viral load detection and CD4+ T lymphocyte counting]Xudong Lin
National Center for AIDS Prevention and Control, Beijing 100050, China
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 16:211-4. 2002..As for the chinese herbs treatment, these two monitors did not reflect changes in clinical status...
