Liang Wei Chen

Summary

Affiliation: Shaanxi Province
Country: China

Publications

  1. ncbi Noradrenergic neurons expressing substance P receptor (NK1) in the locus coeruleus complex: a double immunofluorescence study in the rat
    L W Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an, PR China
    Brain Res 873:155-9. 2000
  2. ncbi Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease
    Liang Wei Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR China
    CNS Neurol Disord Drug Targets 6:273-81. 2007
  3. ncbi Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/Bl mice
    Liang Wei Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, People s Republic of China
    J Comp Neurol 497:898-909. 2006
  4. ncbi Reactive astrocytes as potential manipulation targets in novel cell replacement therapy of Parkinson's disease
    Liang Wei Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR China
    Curr Drug Targets 6:821-33. 2005
  5. ncbi Identification of brain-derived neurotrophic factor in nestin-expressing astroglial cells in the neostriatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice
    L W Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR People s Republic of China
    Neuroscience 126:941-53. 2004
  6. ncbi Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease
    L W Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, P R China
    Curr Drug Targets 5:197-206. 2004
  7. ncbi The striatal GABA-ergic neurons expressing substance P receptors in the basal ganglia of mice
    L W Chen
    Institute of Neurosciences, Fourth Military Medical University, 710032, Xi an, China
    Neuroscience 119:919-25. 2003
  8. ncbi Nestin-containing cells express glial fibrillary acidic protein in the proliferative regions of central nervous system of postnatal developing and adult mice
    L C Wei
    Department of Radiotherapy, Xijing Hospital, The Fourth Military Medical University, Xi an 710032, PR China
    Brain Res Dev Brain Res 139:9-17. 2002
  9. ncbi Cholinergic neurons expressing neuromedin K receptor (NK3) in the basal forebrain of the rat: a double immunofluorescence study
    L W Chen
    Institute of Neuroscience, The Fourth Military Medical University, 710032, Xi an, PR China
    Neuroscience 103:413-22. 2001
  10. ncbi Cholinergic neurons expressing substance P receptor (NK(1)) in the basal forebrain of the rat: a double immunocytochemical study
    L W Chen
    Institute of Neuroscience, The Fourth Military Medical University, 710032, Xi an, PR China
    Brain Res 904:161-6. 2001

Collaborators

Detail Information

Publications38

  1. ncbi Noradrenergic neurons expressing substance P receptor (NK1) in the locus coeruleus complex: a double immunofluorescence study in the rat
    L W Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an, PR China
    Brain Res 873:155-9. 2000
    ..The present study has provided morphological evidence for direct physiological modulation of noradrenergic neurons by tachykinins through SPR in locus coeruleus complex (A5-A7)...
  2. ncbi Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease
    Liang Wei Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR China
    CNS Neurol Disord Drug Targets 6:273-81. 2007
    ..New pharmaceutical strategies against PD will hopefully be discovered by understanding the various active entities and valuable combinations that contribute to the biological effects of Chinese herbs and herbal extracts...
  3. ncbi Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/Bl mice
    Liang Wei Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, People s Republic of China
    J Comp Neurol 497:898-909. 2006
    ..These nestin-expressing reactive astrocytes may therefore play neurotrophic roles in neural remodeling of the basal ganglia in Parkinson's disease...
  4. ncbi Reactive astrocytes as potential manipulation targets in novel cell replacement therapy of Parkinson's disease
    Liang Wei Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR China
    Curr Drug Targets 6:821-33. 2005
    ..Novel pharmaceutical and cell replacement strategies will hopefully be developed by potential manipulation of reactive astrocytes in the basal ganglia in prevention and treatment of Parkinson's disease...
  5. ncbi Identification of brain-derived neurotrophic factor in nestin-expressing astroglial cells in the neostriatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice
    L W Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR People s Republic of China
    Neuroscience 126:941-53. 2004
    ....
  6. ncbi Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease
    L W Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, P R China
    Curr Drug Targets 5:197-206. 2004
    ....
  7. ncbi The striatal GABA-ergic neurons expressing substance P receptors in the basal ganglia of mice
    L W Chen
    Institute of Neurosciences, Fourth Military Medical University, 710032, Xi an, China
    Neuroscience 119:919-25. 2003
    ....
  8. ncbi Nestin-containing cells express glial fibrillary acidic protein in the proliferative regions of central nervous system of postnatal developing and adult mice
    L C Wei
    Department of Radiotherapy, Xijing Hospital, The Fourth Military Medical University, Xi an 710032, PR China
    Brain Res Dev Brain Res 139:9-17. 2002
    ....
  9. ncbi Cholinergic neurons expressing neuromedin K receptor (NK3) in the basal forebrain of the rat: a double immunofluorescence study
    L W Chen
    Institute of Neuroscience, The Fourth Military Medical University, 710032, Xi an, PR China
    Neuroscience 103:413-22. 2001
    ..The present study has provided morphological evidence for direct physiological modulation or regulation of cholinergic neurons by tachykinins through the neuromedin K receptor in the basal forebrain of rats...
  10. ncbi Cholinergic neurons expressing substance P receptor (NK(1)) in the basal forebrain of the rat: a double immunocytochemical study
    L W Chen
    Institute of Neuroscience, The Fourth Military Medical University, 710032, Xi an, PR China
    Brain Res 904:161-6. 2001
    ..The present study has provided morphological evidence for direct physiological modulation of cholinergic neurons by tachykinins through substance P receptor in the basal forebrain of the rat...
  11. ncbi Retinal dopaminergic neurons (A17) expressing neuromedin K receptor (NK(3)): a double immunocytochemical study in the rat
    L W Chen
    Institute of Neuroscience, The Fourth Military Medical University, 710032, Xi an, People s Republic of China
    Brain Res 885:122-7. 2000
    ..The present study has provided morphological evidence for direct physiological modulation of dopaminergic neurons by tachykinins through NKR in the rat retina (A17)...
  12. ncbi Differential expression of AMPA receptor subunits in dopamine neurons of the rat brain: a double immunocytochemical study
    L W Chen
    Institute of Neuroscience, The Fourth Military Medical University, Xi an 710032, PR China
    Neuroscience 106:149-60. 2001
    ..This distribution may provide the basis for a selective dopamine neuron loss in neurodegenerative disorders, such as Parkinson's disease...
  13. ncbi Significant up-regulation of nestin protein in the neostriatum of MPTP-treated mice. Are the striatal astrocytes regionally activated after systemic MPTP administration?
    L W Chen
    Institute of Neuroscience, Fourth Military Medical University, Xi an 710032, PR China
    Brain Res 925:9-17. 2002
    ....
  14. ncbi Neurokinin-3 peptide instead of neurokinin-1 synergistically exacerbates kainic acid-inducing degeneration of neurons in the substantia nigra of mice
    Liang Wei Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an, China
    J Neurochem 105:203-16. 2008
    ....
  15. ncbi Fluoro-Jade C can specifically stain the degenerative neurons in the substantia nigra of the 1-methyl-4-phenyl-1,2,3,6-tetrahydro pyridine-treated C57BL/6 mice
    Gan Lan Bian
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR China
    Brain Res 1150:55-61. 2007
    ..Taken together with previous observations, this study has presented that Fluoro-Jade C can be sensitively and specifically utilized to identify the neuronal degeneration in the substantia nigra of rodent animals receiving MPTP insult...
  16. ncbi Identification and kainic acid-induced up-regulation of low-affinity p75 neurotrophin receptor (p75NTR) in the nigral dopamine neurons of adult rats
    Yan Qin Wang
    Institute of Neurosciences, The Fourth Military Medical University, 17 Changle West Road, Xi an 710032, PR China
    Neurochem Int 53:56-62. 2008
    ....
  17. ncbi Nestin small interfering RNA (siRNA) reduces cell growth in cultured astrocytoma cells
    Li Chun Wei
    Department of Radiotherapy, Xijing Hospital, The Fourth Military Medical University, Xi an 710032, PR China
    Brain Res 1196:103-12. 2008
    ....
  18. ncbi Enhancement of nestin protein-immunoreactivity induced by ionizing radiation in the forebrain ependymal regions of rats
    Mei Shi
    Department of Radiotherapy, Xijing Hospital, The Fourth Military Medical University, Xi an 710032, PR China
    Neurosci Res 44:475-81. 2002
    ....
  19. ncbi Electro-acupuncture of Foot YangMing regulates gastric activity possibly through mediation of the dorsal vagal complex
    Jing Jie Wang
    Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, China
    Am J Chin Med 35:455-64. 2007
    ..Our study suggests that the effect of EA at Tsusanli and Shangchuhsu on the gastric activity may partially depend upon integrated nerve pathway and related central neurons in dorsal vagal complex...
  20. ncbi Differential co-expression of AMPA receptor subunits in substance P receptor-containing neurons of basal forebrain regions of C57/BL mice
    Jin Ping Zhang
    Institute of Neurosciences, The Fourth Military Medical University, Shaanxi, Xi an 710032, PR China
    Neurochem Int 49:319-26. 2006
    ....
  21. ncbi Differential co-localization of neurokinin-3 receptor and NMDA/AMPA receptor subunits in neurons of the substantia nigra of C57/BL mice
    Yan Qin Wang
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, P R China
    Brain Res 1053:207-12. 2005
    ....
  22. ncbi Immunocytochemical localization of substance P receptor in hypothalamic oxytocin-containing neurons of C57 mice
    Hui Ling Liu
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR China
    Brain Res 948:175-9. 2002
    ..The present study provides morphological evidence for tachykinin-induced modulation of oxytocin-containing neurons as mediated by substance P receptor in the hypothalamus of mammals...
  23. ncbi The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice
    Yin Xiu Ding
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, People s Republic of China
    Neurochem Res 36:1759-66. 2011
    ....
  24. ncbi Nigrostriatal neurons in rat express the glial cell line-derived neurotrophic factor receptor subunit c-RET
    Yan Qin Wang
    Institute of Neurosciences, The Fourth Military Medical University, Xi an, People s Republic of China
    Anat Rec (Hoboken) 291:49-54. 2008
    ..Specially, it suggests that c-RET-mediating signaling cascades may play important roles in neuron-glial interaction that support and sustain nigrostriatal neuronal circuits in the basal ganglia...
  25. ncbi Blocking the glial function suppresses subcutaneous formalin-induced nociceptive behavior in the rat
    Li Lan
    Institute of Neurosciences, The Fourth Military Medical University, Changle West Road, Xi an 710032, PR China
    Neurosci Res 57:112-9. 2007
    ..The number of HGJs increased significantly following formalin s.c. injection. It suggests that the Sp5C astrocytes may play an active regulating role in orofacial nociception via Cx32/Cx43 HGJs between astrocytes and neurons of Sp5C...
  26. ncbi Involvement of medullary dorsal horn glial cell activation in mediation of masseter mechanical allodynia induced by experimental tooth movement
    Xiao Dong Liu
    Department of Oral Anatomy and Physiology and TMD, The Fourth Military Medical University, Xi an, Shaanxi, PR China
    Arch Oral Biol 54:1143-50. 2009
    ..To investigate the involvement of microglial and astrocytic activation in the medullary dorsal horn (MDH) during the mediation of masseter area allodynia induced by experimental tooth movement (ETM)...
  27. ncbi Electro-acupuncture of Tsusanli and Shangchuhsu regulates gastric activity possibly through mediation of the vagus-solotary complex
    Jing Jie Wang
    Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi an, China
    Hepatogastroenterology 54:1862-7. 2007
    ..Acupuncture has been reportedly used to treat gastrointestinal diseases, however, its precise mechanism remains unknown...
  28. ncbi Low-Dose Radiation Stimulates Wnt/?-Catenin Signaling, Neural Stem Cell Proliferation and Neurogenesis of the Mouse Hippocampus in vitro and in vivo
    Li Chun Wei
    Institute of Neurosciences, The Fourth Military Medical University, Xi an, 710033, P R China
    Curr Alzheimer Res 9:278-89. 2012
    ....
  29. ncbi Two major distinct subpopulations of neurokinin-3 receptor-expressing neurons in the superficial dorsal horn of the rat spinal cord
    Yu Qiang Ding
    Institute of Neurosciences, Fourth Military Medical University, Xi an 710032, People s Republic of China
    Eur J Neurosci 16:551-6. 2002
    ..e. opioid and nitric oxide...
  30. ncbi Myelin damage of hippocampus and cerebral cortex in rat pentylenetetrazol model
    Yu You
    Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Xi an 710038, PR China
    Brain Res 1381:208-16. 2011
    ..This study firstly provided experimental evidence for myelin sheath damage in PTZ-induced rat's epileptic seizures and further demonstrated that its possible cause was autoimmunoreaction...
  31. ncbi Time-course of neuronal death in the mouse pilocarpine model of chronic epilepsy using Fluoro-Jade C staining
    Lian Wang
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, PR China
    Brain Res 1241:157-67. 2008
    ....
  32. ncbi Differential expression of NMDA and AMPA receptor subunits in DARPP-32-containing neurons of the cerebral cortex, hippocampus and neostriatum of rats
    W-W Wang
    Institute of Neurosciences, The Fourth Military Medical University, Xi'an, 710032, PR China
    Brain Res 998:174-83. 2004
    ....
  33. ncbi Differential expression of AMPA receptor subunits in substance P receptor-containing neurons of the caudate-putamen of rats
    H-J Hu
    Institute of Neurosciences, The Fourth Military Medical University, Xi'an 710032, PR China
    Neurosci Res 49:281-8. 2004
    ....
  34. ncbi [Changes in plasticity of rat hypothalamic neurons and astrocytes in humid and hot environment]
    Ming Qin
    Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, China
    Nan Fang Yi Ke Da Xue Xue Bao 28:419-22. 2008
    ..To study the changes in the plasticity of the neurons and astrocytes in the paraventricular nucleus (PVN) and supraoptic nucleus (SON) of the hypothalamus of rats exposed to a humid and hot environment...
  35. ncbi Molecular manipulation targeting regulation of dopaminergic differentiation and proliferation of neural stem cells or pluripotent stem cells
    Yin Xiu Ding
    Institute of Neurosciences, The Fourth Military Medical University, Xi an, 710032, P R China
    CNS Neurol Disord Drug Targets 10:517-28. 2011
    ....
  36. ncbi Molecular targeting regulation of proliferation and differentiation of the bone marrow-derived mesenchymal stem cells or mesenchymal stromal cells
    Bei Yu Chen
    Institute of Neurosciences, The Fourth Military Medical University, Xi an 710032, China
    Curr Drug Targets 13:561-71. 2012
    ....
  37. ncbi The lumbar spinal cord glial cells actively modulate subcutaneous formalin induced hyperalgesia in the rat
    Ming Qin
    Institute of Neurosciences, The Fourth Military Medical University, Changle West Road, Xi'an 710032, PR China
    Neurosci Res 55:442-50. 2006
    ..t.). It suggests that spinal cord glial cells may play an important role for modulation of hyperalgesia induced by noxious stimuli through HGJs which located between astrocytes and neurons...
  38. ncbi Quantitative study of the coexpression of Fos and N-methyl-D aspartate (NMDA) receptor subunits in otolith-related vestibular nuclear neurons of rats
    Liang-Wei Chen
    Department of Physiology, Faculty of Medicine, The University of Hong Kong, Hong Kong, People's Republic of China
    J Comp Neurol 460:292-301. 2003
    ....