Research Topics
Species | Bing LiuSummaryAffiliation: Institute of Automation Country: China Publications
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Detail Information
Publications
A combinational feature selection and ensemble neural network method for classification of gene expression dataBing Liu
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100080, P R China
BMC Bioinformatics 5:136. 2004..In this paper, we attempt to introduce a combinational feature selection method in conjunction with ensemble neural networks to generally improve the accuracy and robustness of sample classification...- Haplotypes of catechol-O-methyltransferase modulate intelligence-related brain white matter integrityBing Liu
LIAMA Center for Computational Medicine, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, PR China
Neuroimage 50:243-9. 2010..Our findings suggest that COMT haplotypes can nonlinearly modulate the intelligence-related white matter integrity of the prefrontal lobes by more significantly influencing prefrontal dopamine variations than does val158met... - Prefrontal-related functional connectivities within the default network are modulated by COMT val158met in healthy young adultsBing Liu
LIAMA Center for Computational Medicine, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, People s Republic of China
J Neurosci 30:64-9. 2010..Our findings suggest that default network connectivity that involves the prefrontal cortex is modulated by COMT val(158)met through differential effects on prefrontal dopamine levels... - Effects of BDNF Val66Met polymorphism on brain metabolism in Alzheimer's diseaseCunlu Xu
LIAMA Center for Computational Medicine, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China
Neuroreport 21:802-7. 2010..For those with Alzheimer's disease, we also found additional differences in the bilateral insula between the carriers and noncarriers... - A systems biology-based gene expression classifier of glioblastoma predicts survival with solid tumorsJing Zhang
LIAMA Center for Computational Medicine, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, The People s Republic of China
PLoS ONE 4:e6274. 2009..Our results demonstrate that the systems biology-based approach enables to identify common survival-associated genes... - Characterizing the dynamic connectivity between genes by variable parameter regression and Kalman filtering based on temporal gene expression dataQinghua Cui
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100080, People's Republic of China
Bioinformatics 21:1538-41. 2005..The changes of connectivity in simulated data are closely identical with the truth and the results of two pairs of gene expression data show that our method has successfully demonstrated the dynamic connectivity between genes. CONTACT: ... - Cortical thickness is associated with different apolipoprotein E genotypes in healthy elderly adultsMing Fan
LIAMA Center for Computational Medicine, National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, PR China
Neurosci Lett 479:332-6. 2010..05) than did the varepsilon4 carriers. These findings suggest that the different alleles of the APOE gene have distinct neuroanatomic effects in elderly healthy subjects and may play specific roles in the development of AD... - Hippocampal volume and asymmetry in mild cognitive impairment and Alzheimer's disease: Meta-analyses of MRI studiesFeng Shi
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China
Hippocampus 19:1055-64. 2009..By comparing the left and right hippocampal volume, a consistent left-less-than-right asymmetry pattern is found, but with different extents in control (ES, 0.39), MCI (ES, 0.56), and AD (ES, 0.30) group... - Meta-analysis of the association between the monoamine oxidase-A gene and mood disordersMing Fan
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, PR China
Psychiatr Genet 20:1-7. 2010.... - Recombination rates of human microRNAHuizhi Zhao
LIAMA Center for Computational Medicine and National Lab of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China
Biochem Biophys Res Commun 379:702-5. 2009..These findings reveal patterns in recombination rates of microRNAs that could help in understanding the function, evolution, and disease-related roles of microRNAs... - Modularity in the genetic disease-phenotype networkXingpeng Jiang
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, PR China
FEBS Lett 582:2549-54. 2008..We also found correlations between the modularity and functional genomics as well as its connection to drug-target associations... - Exploring candidate genes for human brain diseases from a brain-specific gene networkBing Liu
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100080, PR China
Biochem Biophys Res Commun 349:1308-14. 2006..And the higher score a gene has, the more likely this gene is a disease-related one. The results suggest that the proposed method is effective, convenient, and applicable in the future genetic studies... - Esub8: a novel tool to predict protein subcellular localizations in eukaryotic organismsQinghua Cui
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100080, P R China
BMC Bioinformatics 5:66. 2004..As the number of new genomes has dramatically increased over recent years, a reliable and efficient system to predict protein subcellular location is urgently needed... - Alignment of two-dimensional electrophoresis gelsGuihua Shi
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100080, PR China
Biochem Biophys Res Commun 357:427-32. 2007..The high accuracy and robustness of the algorithm indicate that it is promising for gel image alignment... - COMT val158met modulates association between brain white matter architecture and IQJun Li
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, P R China
Am J Med Genet B Neuropsychiatr Genet 150:375-80. 2009..Our findings suggest that COMT val158met may contribute to intelligence by affecting the association between IQ and the white matter architecture in the prefrontal lobe and the hippocampal formation... - An efficient semi-unsupervised gene selection method via spectral biclusteringBing Liu
School of Electrical and Electronic Engineering, Nanyang Technology University, Singapore 639798
IEEE Trans Nanobioscience 5:110-4. 2006..e., the lymphoma and the liver cancer data sets, where our method is able to identify a single gene or a two-gene combinations which can lead to predictions with very high accuracy... - Impact of EGFR point mutations on the sensitivity to gefitinib: insights from comparative structural analyses and molecular dynamics simulationsBing Liu
Department of Oncology, McGill University, Montreal, Quebec H3T 1E2
Proteins 65:331-46. 2006..The Plarm algorithm could be readily extended to investigate other drug targets... - Extinction and permanence of a two-prey one-predator system with impulsive effectYujuan Zhang
Applied Mathematics, Dalian University of Technology, Dalian, Liaoning 116024, Peoples Republic of China
Math Med Biol 20:309-25. 2003..Therefore, we can use the stability of the positive periodic solution and its period to control insect pests at acceptably low levels... - Identification of differentially expressed genes in individual bovine preimplantation embryos produced by nuclear transfer: improper reprogramming of genes required for developmentMartha Pfister-Genskow
Infigen, Inc, DeForest, Wisconsin 53532, USA
Biol Reprod 72:546-55. 2005.... - Pathophysiological concentrations of amyloid beta proteins directly inhibit rat brain and recombinant human type II phosphatidylinositol 4-kinase activityBo Wu
Department of Pharmacology, Kansai Medical University, Osaka, Japan
J Neurochem 91:1164-70. 2004..Therefore, pathophysiological concentrations of Abetas directly and reversibly inhibited plasma membrane PI4KII activity, suggesting that plasma membrane PI4KII is a target of Abetas in the pathogenesis of Alzheimer's disease... - Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibiaRui Xin Zhang
Center for Integrative Medicine, School of Medicine, University of Maryland, 3rd Floor, James Kernan Hospital Mansion, 2200 Kernan Drive, Baltimore, MD 21207, USA
Pain 118:125-36. 2005..Further, bone cancer activates spinal glial cells, which may release IL-1beta and other cytokines and contribute to hyperalgesia... - Isolation and expression pattern of RGS21 gene, a novel RGS memberXin Li
State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, People s Republic of China
Acta Biochim Pol 52:943-6. 2005..PCR analysis showed that RGS21 mRNA was expressed ubiquitously in the 16 tissues examined, implying general physiological roles... - Prediction of death for extremely low birth weight neonatesNamasivayam Ambalavanan
Department of Pediatrics, University of Alabama, Birmingham, AL 35249, USA
Pediatrics 116:1367-73. 2005.... - Functional expression of transient receptor potential vanilloid 4 in the mouse cochleaJing Shen
Hearing Research Laboratory, Department of Otolaryngology, Kansai Medical University, Moriguchi, Japan
Neuroreport 17:135-9. 2006..In conclusion, transient receptor potential vanilloid 4 may function as an osmosensory and a mechanosensory receptor in the cochlea... - Nucleoplasmin facilitates reprogramming and in vivo development of bovine nuclear transfer embryosJeffery M Betthauser
Infigen, Inc, Madison, Wisconsin 53718, USA
Mol Reprod Dev 73:977-86. 2006..These data suggest that addition of chromatin remodeling factors to the oocyte may improve development of NT embryos by facilitating reprogramming of the somatic nucleus... - Expressions of PDGF-B and collagen type III in the remodeling of experimental saccular aneurysm in ratsBing Liu
Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China
Neurol Res 30:632-8. 2008..So, PDGF-B may induce the expression of MMP for the degradation of collagen type III on the wall of the saccular aneurysms. This may be one of the important mechanisms on the pathogenesis of the saccular aneurysm... - Gene network inference via structural equation modeling in genetical genomics experimentsBing Liu
Department of Statistics, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 0477, USA
Genetics 178:1763-76. 2008..The SEM algorithm was evaluated using data simulated with nonlinear ordinary differential equations and known cyclic network topologies and was applied to a real yeast data set... - Electroacupuncture attenuates bone cancer pain and inhibits spinal interleukin-1 beta expression in a rat modelRui Xin Zhang
Center for Integrative Medicine, School of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
Anesth Analg 105:1482-8, table of contents. 2007.... - Case-only study of interactions between metabolic enzymes and smoking in colorectal cancerChunhong Fan
Department of Epidemiology and Health Statistics, School of Public Health, Zhejiang University, Hangzhou, Zhejiang, China
BMC Cancer 7:115. 2007..Our objective was to measure the interactions between common polymorphisms of P450 (CYP1A2, CYP1B1, CYP2E1), GSTM1 and T1, SULT1A1 and cigarette smoking in colorectal cancer (CRC)... - [Clinical analysis to 36 cases of acute laryngeal damage]Bing Liu
Department of Otolaryngology, Sichuan Province Hospital, Chengdu 610072
Lin Chuang Er Bi Yan Hou Ke Za Zhi 16:278-9. 2002....