Research Topics
| Shi Lin ChenSummaryAffiliation: Institute of Medicinal Plant Development Country: China Publications
| Collaborators
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Detail Information
Publications
[Suitability evaluation of Panax quinquefolium's producing area based on TCMGIS- I]Shi Lin Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 33:741-5. 2008..To supply the scientific data for the choice of medicinal plants' producing area through analyzing the suitable area for Panax quinquefolium' growth...- Validation of the ITS2 region as a novel DNA barcode for identifying medicinal plant speciesShilin Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People s Republic of China
PLoS ONE 5:e8613. 2010..The group admits that the two-locus barcode is far from perfect due to the low identification rate, and the search is not over... - De novo sequencing and analysis of the American ginseng root transcriptome using a GS FLX Titanium platform to discover putative genes involved in ginsenoside biosynthesisChao Sun
Institute of Medicinal Plant Development IMPLAD, Chinese Academy of Medical Sciences, Haidian District, Beijing, China
BMC Genomics 11:262. 2010..Its major bioactive constituents are the triterpene saponins known as ginsenosides. However, little is known about ginsenoside biosynthesis in American ginseng, especially the late steps of the pathway... - Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markersHongmei Luo
The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, PR China
BMC Genomics 12:S5. 2011..Triterpene saponins are the bioactive constituents in P. notoginseng. However, available genomic information regarding this plant is limited. Moreover, details of triterpene saponin biosynthesis in the Panax species are largely unknown... - Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmental regulationHongmei Luo
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Haidian District, Beijing, China
BMC Plant Biol 10:209. 2010..We focused on gene discovery in the areas of bioactive compound biosynthesis and transcriptional regulation as well as genetic marker detection in these species... - Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponinsChun Sui
Institute of Medicinal Plant Development IMPLAD, Chinese Academy of Medical Sciences and Peking Union Medical College, NO, 151, Malianwa North Road, Haidian District, Beijing 100193, China
BMC Genomics 12:539. 2011..Consequently, this technology may help to identify the candidate genes involved in the saikosaponin biosynthetic pathway... - Comparative transcriptome sequencing of germline and somatic tissues of the Ascaris suum gonadXuan Ma
Noncoding RNA laboratory, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
BMC Genomics 12:481. 2011..Widespread study of A. suum would be facilitated by more comprehensive genome resources and, to this end, we have produced a gonad transcriptome of A. suum... - Evaluating the feasibility of using candidate DNA barcodes in discriminating species of the large Asteraceae familyTing Gao
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, PR China
BMC Evol Biol 10:324. 2010..Studies evaluating these regions for species identification in the large plant taxon, which includes a large number of closely related species, have rarely been reported... - Polysaccharides from the root of Angelica sinensis promotes hematopoiesis and thrombopoiesis through the PI3K/AKT pathwayChang Liu
Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, PR China
BMC Complement Altern Med 10:79. 2010.... - Antitumor activity and mechanisms of action of total glycosides from aerial part of Cimicifuga dahurica targeted against hepatomaZe Tian
Children s Hospital Informatics Program at Harvard MIT Division of Health Sciences and Technology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
BMC Cancer 7:237. 2007..It is of great interest to examine the antiproliferative activity and mechanisms of total triterpenoid glycosides of C. dahurica and therefore might eventually be useful in the prevention or treatment of Hepatoma... - 454 EST analysis detects genes putatively involved in ginsenoside biosynthesis in Panax ginsengS Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Haidian, Beijing 100193, China
Plant Cell Rep 30:1593-601. 2011..These 454 ESTs will provide the foundation for further functional genomic research into the traditional herb P. ginseng or its closely related species... - Generation and analysis of expressed sequence tags from a cDNA library of the fruiting body of Ganoderma lucidumHongmei Luo
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, 151 Malianwa North Road, Haidian District, Beijing 100193, PR China
Chin Med 5:9. 2010..CONCLUSION: The present study demonstrates a successful application of EST analysis in the discovery of transcripts involved in the secondary metabolite biosynthesis and the developmental regulation of G. lucidum... - Mapping the potential distribution of high artemisinin-yielding Artemisia annua L. (Qinghao) in China with a geographic information systemLinfang Huang
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Chin Med 5:18. 2010..Artemisia annua L. is an important source for artemisinin, a potent drug for treating malaria. This study aims to map and predict the potential geographic distribution of A. annua L. in China... - [Strategies of the study on herb genome program]Shi Lin Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Yao Xue Xue Bao 45:807-12. 2010..HerbGP shall also have significant impacts on the R&D of natural medicines and the development of medicinal farming by analysis of secondary metabolic pathways and selection of cultivars with good agricultural traits... - TCMGIS-II based prediction of medicinal plant distribution for conservation planning: a case study of Rheum tanguticumHua Yu
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China
Chin Med 5:31. 2010..To provide reliable references for conservation planning and regional management, this study focuses on large-scale distribution prediction of Rheum tanguticum Maxim. ex Balf (Dahuang)... - An introduction to the medicinal plant genome projectShilin Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China
Front Med 5:178-84. 2011..This study places the study on traditional Chinese medicine into the frontier field of life science... - Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transportYongzhen Sun
The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, PR China
BMC Genomics 12:533. 2011..Despite its importance, little is known about the transcriptome of C. acuminata and the mechanism of CPT biosynthesis, as only few nucleotide sequences are included in the GenBank database... - [Suitability evaluation of Cistanche desertiola based on TCMGIS-I]Jun Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Chinese Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 32:1396-401. 2007..To analyze the appropriate producing area of Cistanche desertiola... - [Analysis of expressed sequence tags (EST) from Panax quinquefolium root]Shi Lin Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100094, China
Yao Xue Xue Bao 43:657-63. 2008..quinquefolium and it can be applied to the molecular modification of the ginsenosides biosynthetic pathway ultimately for improving the quality of American ginseng germplasm... - [Study on the plant community of Fritillaria cirrhosa]Shi Lin Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100094
Zhongguo Zhong Yao Za Zhi 28:398-402. 2003..To provide scientific basis for natural cultivation of Fritillaria cirrhosa... - Identification of Cistanche species (Orobanchaceae) based on sequences of the plastid psbA-trnH intergenic regionJian Ping Han
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Yao Xue Xue Bao 45:126-30. 2010..066% to 1.224%. Our results suggest that the psbA-trnH intergenic spacer region represent a barcode that can be used to identify Cistanche species and other morphologically undistinguishable species... - EST analysis reveals putative genes involved in glycyrrhizin biosynthesisYing Li
Institute of Medicinal Plant Development IMPLAD, Chinese Academy of Medical Sciences and Peking Union Medical College, NO, 151, Malianwa North Road, Haidian District, Beijing 100193, China
BMC Genomics 11:268. 2010..uralensis, is currently unclear. Identification of candidate genes involved in the glycyrrhizin biosynthetic pathway will significantly contribute to the understanding of the biosynthetic and medicinal chemistry of this compound... - [Rapid and undamaged determination of C. deserticola by Fourier-transform infrared spectroscopy and clustering analysis]Rong Xu
Endangered TCM Propagation and Breeding National Engineering Laboratory, The Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Guang Pu Xue Yu Guang Pu Fen Xi 29:1860-3. 2009..On the whole, combined with clustering analysis, FTIR provides a effective way to evaluate the origin of the Chinese medicines rapidly and undamagedly... - [The sustainable development framework of national Chinese medicine resources]Shi Lin Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Chinese Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 30:1141-6. 2005..It provided external scientific standard for the research of the sustainable development on Chinese medicine resources... - [Chinese meteria medica resources and ecological modernization]Yong Peng
Institute of Modicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 32:1125-7. 2007..Some appropriate measures should be implemented in order to guarantee both the Chinese materia medica resources supply and environment protection... - [Suitability evaluation of Cistanche tubulosa based on TCMGIS-I]Jun Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Chinese Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 33:496-501. 2008..To analyze the appropriate producing area of Cistanche tubulosa by mean of TCMGIS-I... - [Preliminary pharmaphylogenetic study on Ranunculaceae]Yong Peng
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing
Zhongguo Zhong Yao Za Zhi 31:1124-8. 2006..To deal with the correlation between phylogeny, chemical constituents and pharmaceutical aspects of Ranunculaceae, namely a pharmaphylogenic study of this taxon... - [Transcriptome characterization for Salvia miltiorrhiza using 454 GS FLX]Ying Li
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Yao Xue Xue Bao 45:524-9. 2010..Data presented in this study will constitute an important resource for the scientific community that is interested in the molecular genetics and functional genomics of S. miltiorrhiza... - [Review of bioactivities of natural cycloartane triterpenoids]Ze Tian
Institute of Medicinal Plant, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
Zhongguo Zhong Yao Za Zhi 31:625-9. 2006..This will be benefit for the further research and development of the compounds... - Species identification of medicinal pteridophytes by a DNA barcode marker, the chloroplast psbA-trnH intergenic regionXin Ye Ma
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100193, PR China
Biol Pharm Bull 33:1919-24. 2010..Thus, the psbA-trnH intergenic region is a suitable DNA marker for species identification in medicinal pteridophytes... - [Study on application of low altitude remote sensing to Chinese herb medicinal sustainable utilization]Ying qun Zhou
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 33:977-9. 2008..This paper described the technical system, equipment and image processing of low altitude remote sensing, and analyzed its future application in Chinese herb medicinal sustainable utilization... - [Conspectus of ecophysiological study on medicinal plant in wild nursery]Xi wen Li
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 32:1388-92. 2007.... - [Some key problems of quantitative estimation in multilevel remote sensing monitoring system of plant medicinal materials]Cai Xiang Xie
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 33:326-9. 2008.... - [FTIR and 2D-IR spectroscopic studies on different sources of Herbra cistanche]Rong Xu
The Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, National Engineering Laboratory for Breedng of Endangered Medicinal Materials, Beijing 100193, China
Guang Pu Xue Yu Guang Pu Fen Xi 30:897-900. 2010..The three kinds of herbs were quite different from each other in the number and intensity of autopeaks. Therefore, FTIR macro-fingerprint method can identify different sources of Hebra cistance fast, nondestructively and effectively... - [Cloning and bioinformatic analysis of PqERF1 gene in Panax quinquefolius]Yong zhen Sun
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Yao Xue Xue Bao 46:1008-14. 2011..quinquefolius... - [Infrared spectroscopic study on the component and vigor analysis of Cistanche deserticola seeds]Rong Xu
The Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Guang Pu Xue Yu Guang Pu Fen Xi 29:97-101. 2009..The results suggest that FTIR not only can be used in fast comprehensive analysis of seed components, but also can be used in the seed vigor analysis, seed longevity determination and seed quality evaluation... - [Classification of licorice based on inorganic elements characteristics]Ying qun Zhou
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China
Guang Pu Xue Yu Guang Pu Fen Xi 30:1101-4. 2010..In conclusion, the method we founded here turned out to be intuitive, informative, and highly accurate, and can be used to reveal the characteristic of inoganic elements in medicinal plant... - Identification of Dendrobium species by a candidate DNA barcode sequence: the chloroplast psbA-trnH intergenic regionHui Yao
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100193, PR China
Planta Med 75:667-9. 2009..5 %. Our results support the notion that the psbA-trnH intergenic spacer region could be used as a barcode to distinguish various Dendrobium species and to differentiate Dendrobium species from other adulterating species... - [Chemical constituents from stems of Schisandra propinqua]Li Jia Xu
Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 33:521-3. 2008..To study the chemical constituents in the stems of Schisandra propinqua and evaluate their effects on proliferation of vascular smooth muscle cells (VSMCs) in vitro by MTT assay... - Ethnopharmacological investigations on Thalictrum plants in ChinaSi Bao Chen
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100094, China
J Asian Nat Prod Res 5:263-71. 2003..In addition, the correlation between folk therapeutic effects and chemical constituents, and the modem pharmacological activities, are discussed as well as the prospect of isolation and development of new drugs from this genus of plants... - [Ecological evaluation of suitable area for production of Phellodendron amurense based on TCMGIS- I]Feng Mei Suo
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Chinese Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 33:1536-9. 2008..3 m2, the results also indicate some condign regions in Innermongolia municipality. The system is much valuable to the division of adaptive area, introduction and acclimatization of medicinal materials... - [Review of current situations and prospects of research and development on traditional Chinese medicine cosmetics]Meng Zhang
Institute of Medical Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 32:2457-60. 2007..Finally, the developmental prospects of TCMC in China were discussed in two aspects of the strategy of the R&D and the problems facing when it was marketed... - [Identification of daturae flos and its adulterants based on DNA barcoding technique]Jian Ping Han
The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education of PRC, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Yao Xue Xue Bao 46:1408-12. 2011..Samples of Brugmansia arborea were clustered into one clade, and the other species of Datura L. formed another clade. The results showed that either ITS2 or psbA-trnH was useful to identify Daturae Flos from its adulterants... - [Research progress on resources in Bulbus Fritillariae Cirrhosae]Hui Liu
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China
Zhongguo Zhong Yao Za Zhi 33:1645-8. 2008..The present problems and the future research direction on bulbus fritillariae cirrhosae were also discussed... - [UPLC fingerprint for quality assessment of ginsenosides of ginseng radix et rhizoma]Cui ying Zhang
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Yao Xue Xue Bao 45:1296-300. 2010..The quality was assessed by similarity evaluation system for chromatographic fingerprint of TCM (2004B Version). The convenient and high specific method can be used to identify and evaluate the quality of the Ginseng Radix et Rhizoma... - [Simultaneous determination of peimisine and sipeimine in Fritillaria walujewii regel and Fritillaria pallidiflora Schrenk by UPLC-ELSD]Bao zhong Duan
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Yao Xue Xue Bao 45:1541-4. 2010..The average recovery was 94.5% and 98.1% with RSD < or = 2.36%. The UPLC-ELSD method is simple, sensitive and accurate with good repeatability, which is available for quality control of F. walujewii Regel and F. pallidiflora Schrenk... - [Studies on seed quality evaluation technique and grading rules of Cistanche deserticola]Rong Xu
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences Peking Union Medical College, Beijing 100193, China
Zhong Yao Cai 32:475-8. 2009..To establish a seed quality evaluation technique system and quality grading rules for Cistanche deserticola... - [Comparison of the contents of trace elements in the roots of four original danshen (Salvia miltiorrhiza bunge)]Chun E He
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China
Guang Pu Xue Yu Guang Pu Fen Xi 30:801-3. 2010..The difference in the contents of trace elements has an important effect on the research into the contents of officinal ingredients and their curative effect of the roots of four kinds of original danshen germplasm... - Suppression of diet-induced hypercholesterolemia by scutellarin in ratsQing Li
Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, P R China
Planta Med 75:1203-8. 2009..However, whether scutellarin's atheroscleroprotective potential targets endothelial function directly or indirectly on its antioxidative activity remains to be determined...