Zhongzhen Zhao

Summary

Affiliation: Hong Kong Baptist University
Country: China

Publications

  1. ncbi The formation of daodi medicinal materials
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    J Ethnopharmacol 140:476-81. 2012
  2. ncbi Determination of patchoulic alcohol in Herba Pogostemonis by GC-MS-MS
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong
    Chem Pharm Bull (Tokyo) 53:856-60. 2005
  3. ncbi Authentication is fundamental for standardization of Chinese medicines
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong Special Administrative Region, PR China
    Planta Med 72:865-74. 2006
  4. ncbi Macroscopic identification of Chinese medicinal materials: traditional experiences and modern understanding
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    J Ethnopharmacol 134:556-64. 2011
  5. ncbi A unique issue in the standardization of Chinese materia medica: processing
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, P R China
    Planta Med 76:1975-86. 2010
  6. ncbi Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry
    Zhitao Liang
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong SAR, China
    Chin Med 5:29. 2010
  7. ncbi Application of microscopy in authentication of Chinese patent medicine--Bo Ying compound
    Zhong Zhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Microsc Res Tech 67:305-11. 2005
  8. ncbi A systematic study on confused species of Chinese materia medica in the Hong Kong market
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, P R China
    Ann Acad Med Singapore 35:764-9. 2006
  9. ncbi Comparative study on the aristolochic acid I content of Herba Asarifor safe use
    Zhong Zhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, PR China
    Phytomedicine 15:741-8. 2008
  10. ncbi Toxicity assessment of nine types of decoction pieces from the daughter root of Aconitum carmichaeli (Fuzi) based on the chemical analysis of their diester diterpenoid alkaloids
    Guanghua Lu
    Teaching Division, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    Planta Med 76:825-30. 2010

Collaborators

Detail Information

Publications52

  1. ncbi The formation of daodi medicinal materials
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    J Ethnopharmacol 140:476-81. 2012
    ..This review clarifies the concept and rationalizes the formation of daodi medicinal material...
  2. ncbi Determination of patchoulic alcohol in Herba Pogostemonis by GC-MS-MS
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong
    Chem Pharm Bull (Tokyo) 53:856-60. 2005
    ..cablin. The developed method was found to be convenient and facile in particular to tackle the complicated matrix problems always encountered in the herbs which contain high level of essential oils...
  3. ncbi Authentication is fundamental for standardization of Chinese medicines
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong Special Administrative Region, PR China
    Planta Med 72:865-74. 2006
    ..Furthermore, it is proposed that an authority on the authentication of CMM be established, as a physical institution and/or as an electronic database...
  4. ncbi Macroscopic identification of Chinese medicinal materials: traditional experiences and modern understanding
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    J Ethnopharmacol 134:556-64. 2011
    ..This review clarifies the role of macroscopic features in the quality assessment of CMM...
  5. ncbi A unique issue in the standardization of Chinese materia medica: processing
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, P R China
    Planta Med 76:1975-86. 2010
    ..The objective of this paper is to review the literature covering the current situation and problems of CMM processing as well as recent progress in research in this area. A summary of the most urgent work needed is proposed...
  6. ncbi Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry
    Zhitao Liang
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong SAR, China
    Chin Med 5:29. 2010
    ..The present study investigates the differences in chemistry between raw and processed Radix Polygoni Multiflori...
  7. ncbi Application of microscopy in authentication of Chinese patent medicine--Bo Ying compound
    Zhong Zhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Microsc Res Tech 67:305-11. 2005
    ....
  8. ncbi A systematic study on confused species of Chinese materia medica in the Hong Kong market
    Zhongzhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, P R China
    Ann Acad Med Singapore 35:764-9. 2006
    ..The current situation in the Hong Kong market and some suggestions for alleviating the problem are also discussed...
  9. ncbi Comparative study on the aristolochic acid I content of Herba Asarifor safe use
    Zhong Zhen Zhao
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, PR China
    Phytomedicine 15:741-8. 2008
    ..0370.006 microg/g). Therefore, the root portion of Herba Asari was recommended for prescription as a decoction instead of grinding it into powder for oral administration...
  10. ncbi Toxicity assessment of nine types of decoction pieces from the daughter root of Aconitum carmichaeli (Fuzi) based on the chemical analysis of their diester diterpenoid alkaloids
    Guanghua Lu
    Teaching Division, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    Planta Med 76:825-30. 2010
    ....
  11. ncbi Quality assessment of Rhizoma et Radix Notopterygii by HPTLC and HPLC fingerprinting and HPLC quantitative analysis
    Guang Sheng Qian
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    J Pharm Biomed Anal 44:812-7. 2007
    ..Finally, the pharmacologically active marker compounds isoimperatorin, notopterol and bergapten in this herb were quantitatively determined using a validated reverse-phase HPLC method...
  12. ncbi Authentication of Chinese Materia Medica decoction dregs. Part II: comparison before and after decoction of four Chinese Materia Medica that mainly comprise storage tissue
    Lailai Wong
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, People s Republic of China
    Microsc Res Tech 75:164-75. 2012
    ..These differences could be used to authenticate CMM dregs...
  13. ncbi A comparable, chemical and pharmacological analysis of the traditional Chinese medicinal herbs Oldenlandia diffusa and O. corymbosa and a new valuation of their biological potential
    Zhitao Liang
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, PR China
    Phytomedicine 15:259-67. 2008
    ..The results suggest that the mechanism of antitumor activity of O. diffusa may not be attributed to the antiproliferative and antiangiogenic effects...
  14. ncbi A novel method to identify the Chinese herbal medicine Wuzhimaotao by quantification of laticifers
    Dawn Tung Au
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    Microsc Res Tech 72:293-8. 2009
    ..This method is rapid, accurate, and inexpensive...
  15. ncbi Ethnobotanical study of medicinal plants used by Hakka in Guangdong, China
    Dawn Tung Au
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    J Ethnopharmacol 117:41-50. 2008
    ..An ethnobotanical survey was conducted to collect information on the use of medicinal plants by the Hakka living in Guangdong...
  16. ncbi Establishment of HPLC-DAD-MS fingerprint of fresh Houttuynia cordata
    Jiang Meng
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Special Administrative Region, PR China
    Chem Pharm Bull (Tokyo) 53:1604-9. 2005
    ..cordata is critical to assess and represent its overall quality...
  17. ncbi Rapid screening method for intact glucosinolates in Chinese medicinal herbs by using liquid chromatography coupled with electrospray ionization ion trap mass spectrometry in negative ion mode
    Kim Chung Lee
    Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR, China
    Rapid Commun Mass Spectrom 22:2825-34. 2008
    ..Significant variation in the compositions of intact glucosinolates was identified in the cruciferous herbs. This method was applied in the differentiation and quality control of two pairs of easily confused herbs...
  18. ncbi Comparison of the immunoregulatory function of different constituents in radix astragali and radix hedysari
    Jing Liu
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong
    J Biomed Biotechnol 2010:479426. 2010
    ..Polysaccharides comprised the major constituents in RA and HQ. All polysaccharides extract (PE) of the three herbs showed similar levels of immunological effect in both immunological assays...
  19. ncbi Establishment of GC-MS fingerprint of fresh Houttuynia cordata
    Jiang Meng
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong Special Administrative Region, P. R. China
    Chem Pharm Bull (Tokyo) 53:1484-9. 2005
    ..The developed fingerprint can be successfully applied to distinguish between fresh and dry herbs, as well as determining differentiation among different medicinal portions...
  20. ncbi Alkaloid profiling in crude and processed Strychnos nux-vomica seeds by matrix-assisted laser desorption/ionization-time of flight mass spectrometry
    Wei Wu
    Department of Chemistry, Hong Kong Baptist University, Kowloon, Hong Kong SAR, China
    J Pharm Biomed Anal 45:430-6. 2007
    ..Experimental results indicated that the direct MALDI-TOFMS analysis allowed rapid screening of the alkaloid components in Strychnos nux-vomica seeds...
  21. ncbi Comparative analysis of Oldenlandia diffusa and its substitutes by high performance liquid chromatographic fingerprint and mass spectrometric analysis
    Zhitao Liang
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong Special Administrative Region, P R China
    Planta Med 73:1502-8. 2007
    ..In conclusion, it is important to use the above three compounds as chemical markers for quality evaluation and chemical authentication of Herba Oldenlandiae and its substitutes...
  22. ncbi Characterization of shapes for use in classification of starch grains images
    Chong Sze Tong
    Department of Mathematics, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    Microsc Res Tech 71:651-8. 2008
    ....
  23. ncbi Identification of starch grains in microscopic images based on granulometric operations
    Chong Sze Tong
    Department of Mathematics, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Microsc Res Tech 70:724-32. 2007
    ....
  24. ncbi Quantification of zeaxanthin dipalmitate and total carotenoids in Lycium fruits (Fructus Lycii)
    Yong Peng
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Plant Foods Hum Nutr 60:161-4. 2005
    ..The results demonstrated that these methods are reliable and facile techniques for rapid analysis of carotenoids for crude drug and plant-derived food supplements...
  25. ncbi Efficacy and safety of herbal medicines for idiopathic Parkinson's disease: a systematic review
    Vincent Chung
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Mov Disord 21:1709-15. 2006
    ..Current evidence is insufficient to evaluate the efficacy and safety of various HMs. Further studies with improved trial design and reporting, with assessment on cost-effectiveness, quality of life, and qualitative data are warranted...
  26. ncbi Control release effects of binders used in pills of traditional Chinese medicine herbs
    Zhijun Yang
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon
    Chem Pharm Bull (Tokyo) 54:188-95. 2006
    ..The dissolution profiles indicate that changing the ratio of the binders altered the patterns of dissolution of the API; thus, this ration may be used to control the release of API from the pills...
  27. ncbi [Comparative study of wild and cultivated astragali radix in Daqingshan district in Wuchuan of Neimenggu]
    Jing Liu
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong, China
    Zhongguo Zhong Yao Za Zhi 36:1577-81. 2011
    ..To make a comparative study on wild and cultivated Astragali Radix in Wuchuan, Neimenggu where is one of the geo-authentic producing areas of Astragalus membranaceus var. mongholicus...
  28. ncbi Direct analysis of alkaloid profiling in plant tissue by using matrix-assisted laser desorption/ionization mass spectrometry
    Wei Wu
    Department of Chemistry, Hong Kong Baptist University, Kowloon, Hong Kong SAR, China
    J Mass Spectrom 42:58-69. 2007
    ..The rapid collection of information from the direct analysis on plant tissues could be valuable for supporting the discovery of new compounds and for the quality control of medicinal herbs...
  29. ncbi [Microscopic identification study of western herbs. Part I: Three Echinacea-species roots]
    Qin Li
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong, China
    Zhongguo Zhong Yao Za Zhi 34:2718-20. 2009
    ..To make microscopic identification research of three Echinacea-species roots recorded in the United States Pharmacopeia...
  30. ncbi Schisandrol A from Schisandra chinensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp-substrate complexes
    Wang Fun Fong
    School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, P R China
    Planta Med 73:212-20. 2007
    ..Our results suggest that SCH acts by affecting the normal formation and functioning of the Pgp-substrate complexes...
  31. ncbi Quality assessment of radix salviae miltiorrhizae
    Ping Hu
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Chem Pharm Bull (Tokyo) 53:481-6. 2005
    ..The HPLC quantitation methods of the three marker compounds were validated and the measurement uncertainty, which is important for setting the proposed content limit of the marker compounds in herbal medicine, were further evaluated...
  32. ncbi Multi-component HPLC fingerprinting of Radix Salviae Miltiorrhizae and its LC-MS-MS identification
    Ping Hu
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Chem Pharm Bull (Tokyo) 53:677-83. 2005
    ....
  33. ncbi Assay of free ferulic acid and total ferulic acid for quality assessment of Angelica sinensis
    Guang-Hua Lu
    Research and Development Division, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    J Chromatogr A 1068:209-19. 2005
    ..07 +/- 2.73 (mean +/- SD, n = 10). The chemical assay of DG using total ferulic acid content would be a better choice to assess the herbal quality and was recommended...
  34. ncbi Authentication of the 31 species of toxic and potent Chinese Materia medica (T/PCMM) by microscopic technique, part 1: three kinds of toxic and potent animal CMM
    Li Xia
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, People s Republic of China
    Microsc Res Tech 70:960-8. 2007
    ..The results demonstrated that it was feasible to use the present microscopic characters for the authentication of the above three animal T/PCMM...
  35. ncbi Quantitative determination of four diterpenoids in Radix Salviae Miltiorrhizae using LC-MS-MS
    Ping Hu
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Chem Pharm Bull (Tokyo) 53:705-9. 2005
    ..1%, and 95.9% with variation coefficient of 6.0%, 4.3%, 3.7%, and 4.2%, respectively. The established method was successfully applied to the quality assessment of seven batches of RSM samples collected from different regions of China...
  36. ncbi Determination of glucosinolates in traditional Chinese herbs by high-performance liquid chromatography and electrospray ionization mass spectrometry
    Kim-Chung Lee
    Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, People's Republic of China
    Anal Bioanal Chem 386:2225-32. 2006
    ..3 to 14.6%. Analysis of the glucosinolates provided scientific evidence enabling differentiation of three pairs of easily confused plants...
  37. ncbi Authentication of the 31 species of Toxic and Potent Chinese Materia Medica (T/PCMM) by microscopic technique, part 2: Three species of seed T/PCMM
    Li Xia
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Microsc Res Tech 71:325-33. 2008
    ....
  38. ncbi Application of microscopic techniques in authentication of herbal tea--Ku-Ding-Cha
    Chun-Fung Tam
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Microsc Res Tech 69:927-32. 2006
    ..The method was proven to be quick, handy, simple, and convenient...
  39. ncbi DNA-binding affinities and sequence specificities of protoberberine alkaloids and their demethylated derivatives: a comparative study
    Yong Qin
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Chem Biodivers 4:145-53. 2007
    ..The binding mode of these alkaloids was further confirmed by UV spectroscopic titration experiments. All the compounds bind to double-stranded DNA most probably via an intercalating mode...
  40. ncbi Determination of iridoid glucosides for quality assessment of Herba Oldenlandiae by high-performance liquid chromatography
    Zhi Tao Liang
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, P R China
    Chem Pharm Bull (Tokyo) 54:1131-7. 2006
    ..The analytical method is suitable for quality control of Herba Oldenlandiae and useful in differentiation from its confusable species. The method has been fully validated with satisfactory linearity, accuracy, precision and stability...
  41. ncbi [Probe into innovation and development of pattern of quality control and evaluation for Chinese medicine]
    Xiao He Xiao
    PLA Institute of Chinese Meteria Medica, 302 Hospital of PLA, Beijing 100039, China
    Zhongguo Zhong Yao Za Zhi 32:1377-81. 2007
    ..Based on geo-authentic medicinal material and bioassay or biopotency detection, a new pattern of quality control for Chinese medicine could be built and applied...
  42. ncbi Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry
    Guang-Hua Lu
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
    J Chromatogr A 1046:101-7. 2004
    ..The overall analytical procedure is rapid and reproducible which is considered suitable for quantitative analysis of large number of samples...
  43. ncbi Identification of five hepatotoxic pyrrolizidine alkaloids in a commonly used traditional Chinese medicinal herb, Herba Senecionis scandentis (Qianliguang)
    Song Lin Li
    Department of Pharmacology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong SAR
    Rapid Commun Mass Spectrom 22:591-602. 2008
    ..Thus, the current finding of the presence of toxic/tumorigenic PAs in S. scandens challenges the safety of using this TCM herb and its proprietary products...
  44. ncbi Distinguishing the medicinal herb Oldenlandia diffusa from similar species of the same genus using fluorescence microscopy
    Zhi Tao Liang
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Microsc Res Tech 69:277-82. 2006
    ..Specially, the wall of endoderm cells of O. diffusa and O. tenelliflora emit autofluorescence, while similar tissue of O. corymbosa does not. Hence, fluorescence microscopy can be helpful in the identification of CMM...
  45. ncbi [Determination of ligustilide for quality assessment of Ligusticum chuanxiong]
    Shi-Qiong Cheng
    Sichuan Provincial Institute for Food and Drug Control, Chengdu 610036, China
    Zhongguo Zhong Yao Za Zhi 31:1143-6. 2006
    ..The amount of ligustilide in CX samples collected from different cultivation areas was obviously different. However, a relatively higher content of ligustilide was generally found in the CX collected from its main cultivated areas...
  46. ncbi [Study on chemical constituents of flavonoids in fresh herb of Houttuynia cordata]
    Jiang Meng
    School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
    Zhongguo Zhong Yao Za Zhi 31:1335-7. 2006
    ..CONCLUSION: Compounds 1, 2 and 5 were separated from H. cordata for the first time...
  47. ncbi Macropodumines D and E, two new alkaloids with unusual skeletons from Daphniphyllum macropodum Miq
    Zhen Yu Li
    State Key Laboratory of Drug Research, Shanghai Institute of Material Medica, Chinese Academy of Science, Shanghai 201203, People s Republic of China
    Org Lett 9:477-80. 2007
    ..The structures including the relative stereochemistry of new compounds 1 and 2 were elucidated on the basis of detailed spectroscopic data analysis...
  48. ncbi [Orthogonal experiment using SFE-CO2 in extraction of essential oil from fresh Houttuynia cordata and analysis of essential oil by GC-MS]
    Jiang Meng
    School of Chinese Medicine of Hong Kong Baptist University, Hong Kong, China
    Zhongguo Zhong Yao Za Zhi 32:215-7. 2007
    ..To optimize the extraction procedure of essential oil from H. cordata using the SFE-CO2 and analyze the chemical composition of the essential oil...
  49. ncbi [Studies on chemical constituents of phenols in fresh Houttuynia cordata]
    Jiang Meng
    Guangdong Pharmaceutical University, Guangzhou 510000, China
    Zhongguo Zhong Yao Za Zhi 32:929-31. 2007
    ..To study the aqueous constituents of Houttuynia cordata...
  50. ncbi Quantification of two polyacetylenes in Radix Ginseng and roots of related Panax species using a gas chromatography-mass spectrometric method
    Ji hua Liu
    School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China
    J Agric Food Chem 55:8830-5. 2007
    ..This study introduces the first GC-MS method for the quantitative analysis of polyacetylenes in herbs of the Panax genus...
  51. ncbi [Effect of roots of Ficus hirta on cocaine-induced hepatotoxicity and active components]
    Qing Yuan Cai
    Department of Natural Medicines, Peking University School of Pharmaceutical Sciences, Beijing 100083, China
    Zhongguo Zhong Yao Za Zhi 32:1190-3. 2007
    ..To investigate the protective effect of the roots of F. hirta against the cocaine-induced hepatotoxicity and it's active components...
  52. ncbi [Evaluation of measurement uncertainty for the determination of ginsenosides in Radix ginseng by HPLC]
    Ping Hu
    School of Chemistry and Pharmaceutics, East China University of Science and Technology, Shanghai 200237, China
    Yao Xue Xue Bao 40:49-53. 2005
    ..The establishment of the methodology for the evaluation of measurement uncertainty is important to the studies of Chinese materia medica standards...