Research Topics
Species | W C S ChoSummaryCountry: China Publications
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Detail Information
Publications
Nasopharyngeal carcinoma: molecular biomarker discovery and progressWilliam Chi Shing Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Room 1305, 13 F, Block R, 30 Gascoigne Road, Kowloon, Hong Kong SAR, PR China
Mol Cancer 6:1. 2007..In this article, the latest molecular biomarker discovery and progress in NPC is reviewed with respect to the diagnosis, monitoring, treatment and prognostication of the disease...
Contribution of oncoproteomics to cancer biomarker discoveryWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR, PR China
Mol Cancer 6:25. 2007....
Genomic Sequence Analysis of EGFR Regulation by MicroRNAs in Lung CancerLawrence Wc Chan
Room 1305, 13 F, Block R, Department of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
Curr Top Med Chem 12:920-6. 2012..This new strategy that integrates computational and published data approaches provides a fast and effective prediction of miRNAs in specific target genes involved in various diseases...
Exploiting the therapeutic potential of microRNAs in human cancerWilliam Cs Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Room 1305, 13 F, Block R, 30 Gascoigne Road, Kowloon, Hong Kong 852 2958 5441 852 2958 5455
Expert Opin Ther Targets 16:345-50. 2012..Nevertheless, new findings from recent studies and the rapid advances in systemic drug delivery systems provide an optimistic perspective on the evolution of the field...
Cancer research on non-small cell lung cancer in smokers and non-smokers: snapshots from the AACR annual meeting 2009William C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong
Cancer Biol Ther 8:1309-12. 2009..This meeting report aims to provide the readers with a summary of the research highlights on NSCLC in smokers and non-smokers presented in the AACR annual meeting 2009...
Updates in cancer research: insights from the AACR 100th Annual MeetingWilliam C S Cho
Room 1305, 13 F, Block R, Department of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
Expert Rev Mol Diagn 9:411-6. 2009..These and other important presentations from the AACR Annual Meeting 2009 are discussed in this article, which intends to provide updates on the cancer research presented in the most important cancer research meeting in the world...
MicroRNAs in cancer - from research to therapyWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR
Biochim Biophys Acta 1805:209-17. 2010..Here the latest findings of which genes are targeted by each miRNA are reviewed, with particular emphasis on the deciphering of their possible mechanisms and the potential of miRNA-based cancer therapeutics...
MicroRNAs: potential biomarkers for cancer diagnosis, prognosis and targets for therapyWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong
Int J Biochem Cell Biol 42:1273-81. 2010....
Serum amyloid A is elevated in the serum of lung cancer patients with poor prognosisW C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
Br J Cancer 102:1731-5. 2010....
Scientific evidence on the supportive cancer care with Chinese medicineWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR
Zhongguo Fei Ai Za Zhi 13:190-4. 2010....
Conquering cancer through discovery researchWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong
IUBMB Life 62:655-9. 2010..With highlights on the most up-to-date molecular, cellular, clinical, and therapeutic cancer research findings, this article tends to provide a wealth of insights into better understanding of the complexity of cancer...
The role of inflammation in the pathogenesis of lung cancerWilliam Cs Cho
Queen Elizabeth Hospital, Department of Clinical Oncology, Kowloon, Hong Kong
Expert Opin Ther Targets 15:1127-37. 2011..Along with therapeutic benefits, immunotherapy presents the challenges of drug-related toxicities. Gene modification of immunocytokine may lower the associated toxic effects...
Epigenetic alteration of microRNAs in feces of colorectal cancer and its clinical significanceWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Room 1305, 13 F, Block R, 30 Gascoigne Road, Kowloon, Hong Kong
Expert Rev Mol Diagn 11:691-4. 2011..This article evaluates a recently published study investigating the usefulness of epigenetically silenced miRNAs in fecal specimens, including miR-34b/c and miR-148a, as potential markers for CRC screening and prognosis...
Proteome profiling for the identification of lung cancer signaturesWilliam Cs Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Room 1305, 13 F, Block R, 30 Gascoigne Road, Kowloon, Hong Kong
Expert Rev Proteomics 8:689-92. 2011....
Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutationWilliam C S Cho
Department of Clinical Oncology, Room 1305, 3 F, Block R, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
Eur J Cancer 45:2197-206. 2009..The present study focuses on the microRNA (miRNA) expression profiles of this important subset of lung cancer...
Transcatheter arterial chemoembolization combined with or without Chinese herbal therapy for hepatocellular carcinoma: meta-analysisWilliam Cs Cho
Queen Elizabeth Hospital, Department of Clinical Oncology, Room 1305, 13 F, Block R, 30 Gascoigne Road, Kowloon, Hong Kong
Expert Opin Investig Drugs 18:617-35. 2009..This study aims to systemically review the efficacy of Chinese herbal therapy in HCC patients receiving TACE...
Clinical efficacy of traditional Chinese medicine as a concomitant therapy for nasopharyngeal carcinoma: a systematic review and meta-analysisWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR, China
Cancer Invest 27:334-44. 2009..There were 16 Chinese herbs found to be commonly used across the studies. Published studies suggest that TCM is efficacious as a concomitant therapy for NPC patients. These results require confirmation with rigorously controlled trials...
[Progress of treatment for bladder cancer]William Chi-Shing Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR, China
Zhong Xi Yi Jie He Xue Bao 5:85-91. 2007
In vitro and in vivo anti-tumor effects of Astragalus membranaceusWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR, People s Republic of China
Cancer Lett 252:43-54. 2007..Collectively, the results showed that A. membranaceus could exhibit both in vitro and in vivo anti-tumor effects, which might be achieved through activating the anti-tumor immune mechanism of the host...
Oncoproteomics: current trends and future perspectivesWilliam C S Cho
Queen Elizabeth Hospital, Department of Clinical Oncology, Kowloon, Hong Kong SAR, PR China
Expert Rev Proteomics 4:401-10. 2007..In this review, the development and advancement of oncoproteomics technologies for cancer research in recent years are expounded...
In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceusWilliam Chi Shing Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong, SAR, China
J Ethnopharmacol 113:132-41. 2007..Collectively, the results clearly showed that AI could exhibit immunomodulating and immunorestorative effects, both in vitro and in vivo...
A future of cancer prevention and cures: highlights of the Centennial Meeting of the American Association for Cancer ResearchW C Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR, PR China
Ann Oncol 19:205-11. 2008..For those who did not attend the meeting, this report may serve as a highlight of this important international cancer research meeting...
Proteomics technologies and challengesWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong, China
Genomics Proteomics Bioinformatics 5:77-85. 2007..Nevertheless, proteomics is the foundation for constructing and extracting useful knowledge to biomedical research. In this review, a snapshot of contemporary issues in proteomics technologies is discussed...
OncomiRs: the discovery and progress of microRNAs in cancersWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Room 1305, 13 F, Block R, 30 Gascoigne Road, Kowloon, Hong Kong SAR, PR China
Mol Cancer 6:60. 2007..The paper ends with a brief perspective to the future of oncomiRs...
Potentially useful biomarkers for the diagnosis, treatment and prognosis of lung cancerWilliam Chi Shing Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Room 1305, 13 F, Block R, 30 Gascoigne Road, Hong Kong
Biomed Pharmacother 61:515-9. 2007..It is intended for policy makers, researchers, clinicians and other health professionals, offering a variety of useful biomarkers and updated data of clinical trials for lung cancer...
Application of proteomics in Chinese medicine researchWilliam Chi Shing Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR, PR China
Am J Chin Med 35:911-22. 2007....
Latest discoveries and trends in translational cancer research: highlights of the 2008 Annual Meeting of the American Association for Cancer ResearchWilliam C S Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR, PR China
Technol Cancer Res Treat 7:269-77. 2008..For those who did not attend the meeting, this report may serve as a highlight of this important international cancer research meeting...
